Results 71 to 80 of about 18,497 (276)

Dextrans in Aqueous Solution. Experimental Review on Intrinsic Viscosity Measurements and Temperature Effect [PDF]

, 2014
The study of biopolymers as dextran in aqueous solution, is effectively determined by intrinsic viscosity [η] measurements at different temperatures. Molecular weight (Mv) and hydrodynamic properties can be calculated from there.
Masuelli, Martin Alberto
core   +2 more sources

An Ultrafast Self‐Gelling Versatile Hydrogel for Rapid Infected Burn Wound Repair in Military Medicine

Advanced Functional Materials, EarlyView.
A self‐gelling PG@PAC (POD/Gel‐CDH@PA/CHX) powder is developed for infected burn care in austere settings. Upon contact with wound exudate, it instantly forms an adhesive hydrogel, providing simultaneous hemostasis, broad‐spectrum antibacterial activity, reactive oxygen species scavenging, and immunomodulation. In a murine model of S.
Liping Zhang, Zhangrui Wu, Xiansheng Zhao, Geng Wang, Quyang Yang, Minxia zhang, Xiaowei Wang, Xiujun Cheng, Changyue Wu, Dan Wu, Yutian Yang, Canbin Dong, Tao Zhang, Weiqiang Tan, Ningwen Zhu   +14 more
wiley   +1 more source

A Novel Method to Image Macropinocytosis in Vivo

Frontiers in Neuroscience, 2018
Here we described an experimental protocol for in vivo imaging of macropinocytosis and subsequent intracellular events. By microinjection, we delivered fluorescence dextrans together with or without ATPγS into transparent Drosophila melanogaster embryos.
Lunhao Chen, Lunhao Chen, Daxiao Cheng, Jiachen Chu, Jiachen Chu, Ting Zhang, Zhuoer Dong, Huifang Lou, Liya Zhu, Yijun Liu   +9 more
doaj   +1 more source

Unveiling Multidimensional Physicochemical Design Principles for Tissue Processing Hydrogels

Advanced Functional Materials, EarlyView.
This study establishes a materials‐based design framework for polymer hydrogels in tissue clearing, linking physicochemical properties to performance in tissue processing, labeling, and imaging. By analyzing rheology, swelling, porosity, antibody diffusion, mechanical performance, and thermochemical stability across platforms, this work provides a ...
Sangjae Kim, Siheon Lee, Jinsoo Na, James Sangmin Choo, Inho Kim, Junsang Doh, Jeong‐Yun Sun, Chang Yeol Lee, Juhyuk Park   +8 more
wiley   +1 more source

Blood-brain barrier disruption in CCL2 transgenic mice during pertussis toxin-induced brain inflammation [PDF]

, 2012
BACKGROUND: The chemokine CCL2 has an important role in the recruitment of inflammatory cells into the central nervous system (CNS). A transgenic mouse model that overexpresses CCL2 in the CNS shows an accumulation of leukocytes within the perivascular ...
Buist, Richard, Del Bigio, Marc R, Khorooshi, Reza, Owens, Trevor, Peeling, James, Schellenberg, Angela E, Toft-Hansen, Henrik   +6 more
core   +1 more source

Gold Nanoclusters as Dual Agents for Engineering Tumor Vascular Leakiness and Performing Photothermal Therapy

Advanced Functional Materials, EarlyView.
Many cancer nanotherapeutics, while potent, suffer from the inability to escape from the tumor vasculature, especially in the absence of endothelial permeability. In this work, ultrasmall gold nanoclusters could engineer nanomaterials induced endothelial leakiness (NanoEL) and harness strong NIR induced photothermal characteristics to suppress tumor ...
Nengyi Ni, Kuoran Xing, Bihan Zhang, Baoteng Wang, Yinglu Chen, Jianping Xie, Xiao Sun, Jinping Wang, David Tai Leong   +8 more
wiley   +1 more source

Altered Nrf2 signaling mediates hypoglycemia-induced blood-brain barrier endothelial dysfunction in vitro.

PLoS ONE, 2015
Hypoglycemia impairs blood-brain barrier (BBB) endothelial function; a major hallmark in the pathogenesis of various CNS disorders. Previously, we have demonstrated that prolonged hypoglycemic exposure down-regulated BBB endothelial NF-E2 related factor ...
Ravi K Sajja, Kayla N Green, Luca Cucullo   +2 more
doaj   +1 more source

Increased Plasma Colloid Osmotic Pressure Facilitates the Uptake of Therapeutic Macromolecules in a Xenograft Tumor Model

Neoplasia: An International Journal for Oncology Research, 2009
Elevated tumor interstitial fluid pressure (TIFP) is a characteristic of most solid tumors. Clinically, TIFP may hamper the uptake of chemotherapeutic drugs into the tumor tissue reducing their therapeutic efficacy.
Matthias Hofmann, Emmet McCormack, Maja Mujic, Maila Roßberg, August Bernd, Jürgen Bereiter-Hahn, Bjørn Tore Gjertsen, Helge Wiig, Stefan Kippenberger   +8 more
doaj   +1 more source

Experimental study of the effects of hypochlorite on polysulfone membrane properties [PDF]

, 2006
Although chemical solutions are widely employed to clean membranes, they can also be responsible for changes in membrane properties. The two major drawbacks are then either the functional properties of the membrane gradually change, so the production can
Aimar, Pierre, Causserand, Christel, Rouaix, Sandrine   +2 more
core   +2 more sources

In Situ 3D Bioprinting: Impact of Cross‐Linking on the Adhesive Properties of Hydrogels

Advanced Functional Materials, EarlyView.
In situ 3D bioprinting enables the direct deposition of cell‐laden, adhesive biomaterials for on‐site tissue regeneration. This review provides a comprehensive overview of how cross‐linking influences the bioadhesive properties of hydrogels used in 3D bioprinting, highlighting cross‐linking triggers, bioadhesion mechanisms, polymer interpenetration ...
Odile Romero Fernandez, Mulazim Hussain Asim, Shumaila Arshad, Gergely Kali, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source