Results 61 to 70 of about 16,325 (177)

Apparent Bilateral Aldosterone Suppression During Adrenal Vein Sampling: An Artefact of the Liaison Chemiluminescence Immunoassay and Other Causes Revealed by Comparisons With Another Commercial Immunoassay and Mass Spectrometry

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Subtyping of primary aldosteronism usually requires adrenal vein sampling (AVS). Interpretation can be compromised by apparent bilateral aldosterone suppression (ABAS), which we hypothesised reflects an artefact of the Liaison immunoassay of aldosterone.
Christina Pamporaki, Carmina T. Fuss, Ralph Kickuth, Lydia Kürzinger, Mirko Peitzsch, Sybille Fuld, Manuel Schulze, Jun Yang, Martin Reincke, Sven Gruber, Felix Beuschlein, Jacques W. M. Lenders, Graeme Eisenhofer   +12 more
wiley   +1 more source

Ample Evidence: Dehydroepiandrosterone (DHEA) Conversion into Activated Steroid Hormones Occurs in Adrenal and Ovary in Female Rat.

PLoS ONE, 2015
Dehydroepiandrosterone (DHEA) is important for human health, especially for women. All estrogens and practically half of androgens are synthesized from DHEA in peripheral tissues.
Yingqiao Zhou, Jian Kang, Di Chen, Ningning Han, Haitian Ma   +4 more
doaj   +1 more source

Effect of Dehydroepiandrosterone on Lipemia, Glucose Tolerance, Insulinemia, Insulin Binding to Erythrocytes in SHR/N-cp Lean Rats of Koletsky Type

Acta Medica, 1997
Experiments were performed in the genetically hypertensive lean males of Koletsky type. It was monitored the effect of dehydroepiandrosterone (DHEA) treatment on lipemia, glucose tolerance, insulinemia, insulin binding to erythrocytes, fat pads, body ...
Věroslav Golda, Jiřina Hilgertová
doaj   +1 more source

Inositol and Berberine Synergistically Reprogram Endocrine and Ovarian Metabolism in Polycystic Ovary Syndrome

Cell Proliferation, EarlyView.
In a DHEA+HFD‐induced mouse model, Ins/BBR alleviated mitochondrial defects and broadly reprogrammed metabolic landscape in granulosa cells, in specific, restoring nucleotide pools and amino acid turnover, and preventing abnormal long‐chain fatty acid accumulation.
Juan Ge, Chenxiang Zhang, Yilong Zhao, Haiyang Zhao, Shuai Zhu, Tao Tang, Guorui Zhang, Qiang Wang, Hui Wang   +8 more
wiley   +1 more source

The effect of cinnamon on polycystic ovary syndrome in a mouse model

Reproductive Biology and Endocrinology, 2018
Background Polycystic ovary syndrome (PCOS) is the most prevalent cause of anovulatory infertility and hyperandrogenism. Evidence favors insulin resistance and compensatory hyperinsulinemia as the predominant, perhaps primary, defects in PCOS. The use of
Lei Dou, Yahong Zheng, Lu Li, Xiaowei Gui, Yajuan Chen, Meng Yu, Yi Guo   +6 more
doaj   +1 more source

Steroidogenic compensation and lipid deficiency with enhanced NAD+ salvage in small‐for‐gestational‐age placenta

The FEBS Journal, EarlyView.
Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo, Lorenza Driul, Vanessa Tolotto, Eros Di Giorgio, Luigi E. Xodo   +4 more
wiley   +1 more source

Thriving in Nursing Work: The Association Between Self‐Reports and Biomarkers of Stress, Inflammation and Neuroplasticity

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To examine whether self‐reported thriving at work is associated with biomarkers of stress, inflammation, neuroplasticity and neurodegeneration in nurses. Design A cross‐sectional study. Methods An online questionnaire measuring thriving at work was administered to nurses in a teaching hospital in Michigan, U.S. over 5 weeks in 2024.
Judith E. Arnetz, Eamonn Arble, Jackeline Iseler, Michelle Pena, Nicolina Evola, John Vanschagen, John S. Beck, Scott E. Counts, Bengt B. Arnetz   +8 more
wiley   +1 more source

Deficiency of Gpr1 improves steroid hormone abnormality in hyperandrogenized mice

Reproductive Biology and Endocrinology, 2018
Background Polycystic ovary syndrome (PCOS) is a complex genetic disease with multifarious phenotypes. Many researches use dehydroepiandrosterone (DHEA) to induce PCOS in pubertal mouse models. The aim of this study was to investigate the role of GPR1 in
Ya-Li Yang, Li-Feng Sun, Yan Yu, Tian-Xia Xiao, Bao-Bei Wang, Pei-Gen Ren, Hui-Ru Tang, Jian V. Zhang   +7 more
doaj   +1 more source

Practitioner Review: Infant mental health meets cell and molecular biology – a look to the future

Journal of Child Psychology and Psychiatry, EarlyView.
Background A major research effort in the past two decades has begun to illuminate how experience ‘gets under the skin’ – that is – the cellular and molecular processes that are associated with adversity and resilience. Methods We selectively review three areas of this research: epigenetics, especially DNA methylation, telomere length, and inflammatory
Charles H. Zeanah, Megan Hare, Katherine Cowhey, Stacy S. Drury   +3 more
wiley   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source