Results 71 to 80 of about 17,560 (201)
Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis
Journal of Periodontal Research, EarlyView.A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger +5 more
wiley +1 more source
PLoS ONE, 2015 Dehydroepiandrosterone (DHEA) is important for human health, especially for women. All estrogens and practically half of androgens are synthesized from DHEA in peripheral tissues.
Yingqiao Zhou +4 more
doaj +1 more source
Saliva Liquid Biopsy for Detection of Oral and Systemic Diseases
Journal of Periodontal Research, EarlyView.This Review summarizes and discusses the biological foundations and major classes of salivary biomarkers, outlines collection methods and analytical protocols for saliva‐based liquid biopsy, and technological convergences driven by multi‐omics approaches, artificial intelligence, and point‐of‐care devices in the application of oral and systemic ...
Irene Choi +10 more
wiley +1 more source
Psychophysical Assessment of Gustatory Function in Burning Mouth Syndrome: A Systematic Review
Oral Diseases, EarlyView.ABSTRACT Objective To evaluate whether psychophysically assessed gustatory function differs between adults with burning mouth syndrome and age‐ and sex‐matched healthy controls, and to explore related sensory and physiological factors. Methods This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses ...
Abas Jafari +2 more
wiley +1 more source
The effect of cinnamon on polycystic ovary syndrome in a mouse model
Reproductive Biology and Endocrinology, 2018 Background Polycystic ovary syndrome (PCOS) is the most prevalent cause of anovulatory infertility and hyperandrogenism. Evidence favors insulin resistance and compensatory hyperinsulinemia as the predominant, perhaps primary, defects in PCOS. The use of
Lei Dou +6 more
doaj +1 more source
Effects of DHEA and DHEAS in Neonatal Hypoxic–Ischemic Brain Injury
AntioxidantsNeonatal brain injury remains a significant issue with limited treatment options. This study investigates the potential of the endogenous neurosteroid dehydroepiandrosterone (DHEA) and its sulfate ester (DHEAS) as neuroprotective agents, building on evidence of their mechanisms in adult brain injury models.
Elena Mayer +6 more
openaire +3 more sources
Physiological and anatomical determinants of placental drug transfer
The Journal of Physiology, EarlyView.Abstract figure legend Fetal exposure to pharmaceuticals and their subsequent clearance back to the maternal circulation are governed by placental transfer. Passive diffusion down a maternal‐to‐fetal concentration gradient is the primary route of fetal drug exposure, with specific compounds undergoing transporter‐mediated transfer.
Rohan M. Lewis +3 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor +4 more
wiley +1 more source
Deficiency of Gpr1 improves steroid hormone abnormality in hyperandrogenized mice
Reproductive Biology and Endocrinology, 2018 Background Polycystic ovary syndrome (PCOS) is a complex genetic disease with multifarious phenotypes. Many researches use dehydroepiandrosterone (DHEA) to induce PCOS in pubertal mouse models. The aim of this study was to investigate the role of GPR1 in
Ya-Li Yang +7 more
doaj +1 more source