Results 81 to 90 of about 17,560 (201)

Recent advances in polyendocrine metabolic ovarian syndrome, formerly polycystic ovary syndrome, with emphasis on endocrine and metabolic dysfunction and cardiovascular risk

Journal of Internal Medicine, Volume 300, Issue 5, Page 590-609, November 2026.
Abstract Polyendocrine metabolic ovarian syndrome (PMOS), previously known as polycystic ovary syndrome, affects 10%–13% of women of reproductive age and remains underdiagnosed despite its substantial health burden. The introduction of the new PMOS nomenclature in 2026 reflects a fundamental shift in understanding the condition as a lifelong endocrine ...
Maria Forslund, Johanna Melin, Anju E. Joham, Terhi T. Piltonen, D. Aled Rees, Helena J. Teede   +5 more
wiley   +1 more source

Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis

Advanced Science, Volume 13, Issue 55, 5 October 2026.
A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa, Silke De Vriendt, Lixian Liu, Thalles Fernando Rocha Ruiz, Hugo Vankelecom, Christiani Andrade Amorim   +5 more
wiley   +1 more source

Changes in Cortisol and Testosterone During Acclimatization and the Relationship to Energetic Outcomes

American Journal of Biological Anthropology, Volume 191, Issue 2, October 2026.
ABSTRACT Objectives When in energetically demanding environments (e.g., high altitude, backcountry expeditions), humans acclimatize to compounded intensive stressors. Acclimatization is possible in part by using the dynamically responsive neuroendocrine system, with changes to hormones like cortisol (CORT) and testosterone (T), which both play ...
Mallika S. Sarma, Cara J. Ocobock, Shannon Rochelle, Sarah Martin, Shalender Bhasin, Clare Super, S. Finn Warrick, Lee T. Gettler   +7 more
wiley   +1 more source

Chronic Central Adrenal Insufficiency in a Patient With Remote Traumatic Brain Injury and an Apparently Adequate Standard‐Dose ACTH Response: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT In patients with a remote history of traumatic brain injury, central adrenal insufficiency may remain unrecognized for decades. An apparently adequate response to standard‐dose ACTH stimulation should not preclude further evaluation of the hypothalamic–pituitary–adrenal axis when clinical and biochemical findings continue to suggest adrenal ...
Kazunori Kageyama, Keisuke Sato, Satoshi Yamagata, Mizuki Tasso, Yuki Nakada, Shojiro Sawada   +5 more
wiley   +1 more source

Multidisciplinary Management of a Giant Ovarian Sertoli–Leydig Cell Tumor Presenting With Isosexual Precocious Puberty: A Pediatric Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Sertoli–Leydig cell tumors (SLCTs) are rare ovarian sex cord‐stromal tumors, particularly uncommon in the pediatric population. They are typically androgen‐secreting, while estrogen‐secreting forms are rare and may lead to diagnostic confusion with granulosa cell tumors.
Sanaa Bouramdane, Kenza Elmkaddem, Nawal Hammas, Meryem Boubbou, Othmane Alaoui, Khalid Khattala, Youssef Bouabdellah, Sarra Benmiloud   +7 more
wiley   +1 more source

Modulating the Gut–Ovarian Axis: Mechanistic Rationale and the Limits of Current Evidence for Probiotics in Female Reproductive Aging

Food Science &Nutrition, Volume 14, Issue 10, October 2026.
Selected orally administered probiotics and functional‐food interventions may alter gut microbial ecology and intestinal barrier function. Microbiota‐derived metabolites, microbial components, and endocrine signals—including short‐chain fatty acids, bile acids, tryptophan metabolites, and lipopolysaccharide—may influence systemic immune, metabolic, and
Meiqi Chen, Qi Su, Mengshuang Sun, He Zhang, Jin Xu, Chenxi Zhang, Yanbo Wang   +6 more
wiley   +1 more source

Markers of Systemic Metabolic Dysfunction in Vitiligo and Their Potential Role in Disease Pathogenesis: A Narrative Review

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Vitiligo is a chronic autoimmune disease characterized by the progressive destruction of melanocytes, resulting in depigmented skin macules. While traditionally viewed as a cutaneous disorder driven by a specific CD8+ T cell‐mediated interferon‐γ (IFN‐γ) signature, emerging research suggests that vitiligo may be a systemic condition
Federica Papaccio, Simona Scano, Barbara Bellei   +2 more
wiley   +1 more source

Subclinical cardiac alterations and cardiometabolic profile in adolescents with newly diagnosed polycystic ovary syndrome: A cross‐sectional comparative echocardiographic study

International Journal of Gynecology &Obstetrics, Volume 175, Issue 1, Page 310-321, October 2026.
Abstract Objective While cardiometabolic comorbidities have been well established in adults with polycystic ovary syndrome (PCOS), it remains unclear whether the early signs of cardiovascular morbidity emerge during adolescence. This study aimed to investigate whether metabolic and cardiovascular alterations begin in adolescents with PCOS.
Demet Aygün Ari, Melis Pehlivantürk Kizilkan, Musa Öztürk, İlker Ertuğrul, Hayrettin Hakan Aykan, Tevfik Karagöz, Nuray Kanbur, Orhan Derman, Sinem Akgül   +8 more
wiley   +1 more source

Body, Emotions, and Hormones: A Systematic Review of Body Dissatisfaction, Emotion Regulation, and Puberty in Adolescence

Journal of Adolescence, Volume 98, Issue 7, Page 2207-2244, October 2026.
ABSTRACT Objective Body dissatisfaction often arises from a discrepancy between perceived and ideal body images, posing a risk for psychological issues like depression and eating pathologies, particularly during adolescence. Puberty's rapid physical changes may exacerbate the feeling of dissatisfaction, additionally pubertal changes also influence ...
Isabella Muscolino, Samantha Dockray, Maria Dempsey, Eleonora Tomei   +3 more
wiley   +1 more source

SERUM-CONCENTRATIONS OF Dehydroepyandrosterone-sulfate IN MEN WITH ANDROGENETIC ALOPECIA [PDF]

Journal of IMAB, 2004
Androgenetic alopecia (AA) is considered as a genetically determinate androgen (DHT)-dependent disorder. Theoretically Dehydroepyandrosterone-sulfate (DHEA-S) is the first main metabolite in the androgen metabolism. The aim of the study was to determine
Ani Tsvetanova, Dimitar Gospodinov, Miroslav Donchev   +2 more
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