Results 91 to 100 of about 10,008 (239)

Effects of acute and chronic administration of neurosteroid dehydroepiandrosterone sulfate on neuronal excitability in mice

Drug Design, Development and Therapy, 2016
Dubravka Svob Strac,1 Josipa Vlainic,1 Janko Samardzic,2 Julija Erhardt,3 Zeljka Krsnik41Laboratory for Molecular Neuropsychiatry, Division of Molecular Medicine, Rudjer Boskovic Institute, Zagreb, Croatia; 2Institute of Pharmacology, Clinical ...
Svob Strac D, Vlainic J, Samardzic J, Erhardt J, Krsnik Z   +4 more
doaj  

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Recent advances in polyendocrine metabolic ovarian syndrome, formerly polycystic ovary syndrome, with emphasis on endocrine and metabolic dysfunction and cardiovascular risk

Journal of Internal Medicine, Volume 300, Issue 5, Page 590-609, November 2026.
Abstract Polyendocrine metabolic ovarian syndrome (PMOS), previously known as polycystic ovary syndrome, affects 10%–13% of women of reproductive age and remains underdiagnosed despite its substantial health burden. The introduction of the new PMOS nomenclature in 2026 reflects a fundamental shift in understanding the condition as a lifelong endocrine ...
Maria Forslund, Johanna Melin, Anju E. Joham, Terhi T. Piltonen, D. Aled Rees, Helena J. Teede   +5 more
wiley   +1 more source

Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis

Advanced Science, Volume 13, Issue 55, 5 October 2026.
A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa, Silke De Vriendt, Lixian Liu, Thalles Fernando Rocha Ruiz, Hugo Vankelecom, Christiani Andrade Amorim   +5 more
wiley   +1 more source

Testosterone increases circulating dehydroepiandrosterone sulfate levels in the male rhesus macaque

Frontiers in Endocrinology, 2014
The adrenal steroid dehydroepiandrosterone (DHEA) and its sulfate (DHEAS) are two of the most abundant hormones in the human circulation. Furthermore, they are released in a circadian pattern and show a marked age-associated decline. Adult levels of DHEA
Krystina eSorwell, Steven eKohama, Henryk eUrbanski   +2 more
doaj   +1 more source

Changes in Cortisol and Testosterone During Acclimatization and the Relationship to Energetic Outcomes

American Journal of Biological Anthropology, Volume 191, Issue 2, October 2026.
ABSTRACT Objectives When in energetically demanding environments (e.g., high altitude, backcountry expeditions), humans acclimatize to compounded intensive stressors. Acclimatization is possible in part by using the dynamically responsive neuroendocrine system, with changes to hormones like cortisol (CORT) and testosterone (T), which both play ...
Mallika S. Sarma, Cara J. Ocobock, Shannon Rochelle, Sarah Martin, Shalender Bhasin, Clare Super, S. Finn Warrick, Lee T. Gettler   +7 more
wiley   +1 more source

Polymorphism of SULT2A1 gene and plasma levels of dehydroepiandrosterone sulfate (DHEAS) in individuals with neurocognitive disorder

Neurosteroid dehidroepiandrosteron sulfat (DHEAS) uključen je u brojne moždane funkcije, uključujući učenje, pamćenje, ponašanje, neurogenezu, neuralnu plastičnost i neuroprotekciju.
Balić, Nikola
core   +2 more sources

A Study of the Association between Dehydroepiandrosterone and Frailty in Elderly

Journal of the Indian Academy of Geriatrics, 2018
Objective: To determine the association between dehydroepiandrosterone and frailty in the elderly. Methods: In this cross-sectional analytical study, older people aged 65 and above attending the geriatric outpatient and inpatient services were screened ...
P Aravind Babu, S Deepa
doaj  

Dehydroepiandrosterone Decline in Aging Males as a Predictor of Erectile Dysfunction and Mood Disorders in Patients With Benign Prostate Hyperplasia Undergoing Dutasteride Treatment

American Journal of Men's Health
Age-related decline in dehydroepiandrosterone (DHEA) and its sulfate metabolite, dehydroepiandrosterone-sulfate (DHEAS), affects steroid synthesis in men.
Maja Sofronievska Glavinov, Senol Tahir, Stefan Arsov   +2 more
doaj   +1 more source

Chronic Central Adrenal Insufficiency in a Patient With Remote Traumatic Brain Injury and an Apparently Adequate Standard‐Dose ACTH Response: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT In patients with a remote history of traumatic brain injury, central adrenal insufficiency may remain unrecognized for decades. An apparently adequate response to standard‐dose ACTH stimulation should not preclude further evaluation of the hypothalamic–pituitary–adrenal axis when clinical and biochemical findings continue to suggest adrenal ...
Kazunori Kageyama, Keisuke Sato, Satoshi Yamagata, Mizuki Tasso, Yuki Nakada, Shojiro Sawada   +5 more
wiley   +1 more source