Dehydroepiandrosterone sulfate (DHEAS) is neuroprotective when administered either before or after injury in a focal cortical cold lesion model [PDF]
, 2006 Dehydroepiandrosterone and its sulfate (DHEAS) are sex hormone precursors that exert marked neurotrophic and/or neuroprotective activity in the central nervous system.
Toldi, József +8 more
core +1 more source
DHEA in Elderly Women and DHEA or Testosterone in Elderly Men
Obstetrical & Gynecological Survey, 2006 Dehydroepiandrosterone (DHEA) and testosterone are widely promoted as antiaging supplements, but the long-term benefits, as compared with potential harm, are unknown.We performed a 2-year, placebo-controlled, randomized, double-blind study involving 87 elderly men with low levels of the sulfated form of DHEA and bioavailable testosterone and 57 elderly
NAIR KS +17 more
openaire +4 more sources
Diagnostic testing of autonomous cortisol secretion in adrenal incidentalomas
Endocrine Connections, 2020 Objective: Autonomous cortisol secretion (ACS) is a condition with ACTH-independent cortisol overproduction from adrenal incidentalomas (AI) or adrenal hyperplasia.
Grethe Å Ueland +5 more
doaj +1 more source
Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone-sulfate (DHEAS) and emotional processing — A behavioral and electrophysiological approach [PDF]
, 2015 Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone-sulfate (DHEAS) may have mood enhancement effects: higher DHEAS concentrations and DHEA/cortisol ratio have been related to lower depression scores and controlled trials of DHEA administration have
Manuel Bicho +11 more
core +1 more source
Dose-Response, 2004 Dehydroepiandrosterone sulfate (DHEAS) is a steroid hornone that is synthesized, de novo, in the brain. Endogenous DHEAS levels correlate with the quality of mental and physical health, where the highest levels of DHEAS occur in healthy young adults and ...
David M. Diamond
doaj +1 more source
Tracking of Serum DHEAS Concentrations from Age 1 to 6 Years : A Prospective Cohort Study [PDF]
, 2020 Context: Adrenarche is a gradual process, but its programming is unknown. Objective: The objective of this article is to examine the trajectory of dehydroepiandrosterone sulfate (DHEAS) from age 1 to 6 years and the associations of early growth with ...
Karvonen, Anne M. +5 more
core +1 more source
Dehydroepiandrosterone Sulfate Reduces Acoustic Injury of the Guinea-Pig Cochlea
Journal of Pharmacological Sciences, 2005 The present study was performed to determine effects of dehydroepiandrosterone sulfate (DHEAS), a neurosteroid, on acoustic injury. Albino guinea pigs were exposed to a 2 kHz pure tone of 120 or 125 dB sound pressure level for 10 min immediately after ...
Keiji Tabuchi +6 more
doaj +1 more source
Novel Approaches for Detection Fluorescent-Labeled by Cellvizio Lab System on Hippocampal CA1 Region
Biology, Medicine & Natural Product Chemistry, 2019 Neurosteroids have been identified in the 1981. Dehydroepiandrosterone sulphate (DHEAS) is one of the vital neurosteroids that de novo synthesized in the nervous system from cholesterol precursor (Baulieu & Robel, 1998).
Asma Ulhusna Shaimi +5 more
doaj +1 more source
Annals of Human Biology, 2017 Background: Dehydroepiandrosterone sulphate (DHEAS), the most plentiful circulating adrenal hormone, may be considered as a marker of the onset of adrenarche and is involved in pubertal development and metabolic disorders.
Hongjuan Li +3 more
doaj +1 more source
A SULT2A1 genetic variant identified by GWAS as associated with low serum DHEAS does not impact on the actual DHEA/DHEAS ratio [PDF]
, 2013 DHEA is the major precursor of human sex steroid synthesis and is inactivated via sulfonation to DHEAS. A previous genome-wide association study related the single nucleotide polymorphism (SNP) rs2637125, located near the coding region of DHEA ...
Arlt, W. +9 more
core +1 more source