Results 41 to 50 of about 10,008 (239)
Association of adrenal function and disease severity in community-acquired pneumonia.
PLoS ONE, 2014 IntroductionRapid and accurate risk stratification in patients with community-acquired pneumonia (CAP) is an unmet clinical need. Cortisol to dehydroepiandrosterone (DHEA) ratio was put forward as a prognostic marker in sepsis.
Cornelia Mueller +9 more
doaj +1 more source
NeuroImage: Clinical, 2021 Background: Major depressive disorder (MDD) is a leading cause of disease burden and shows a marked sexual dimorphism. Previous studies reported changes in cerebral perfusion in MDD, an association between perfusion and dehydroepiandrosterone sulfate ...
Christopher Ritter +7 more
doaj +1 more source
DHEA-Bodipy—A functional fluorescent DHEA analog for live cell imaging [PDF]
Molecular and Cellular Endocrinology, 2010 The androgen dehydroepiandrosterone (DHEA) has been reported to protect neuronal cells against dysfunction and apoptosis. Several signaling pathways involved in these effects have been described but little is known about the intracellular trafficking of DHEA.
Lemcke, Susanne +6 more
openaire +2 more sources
Drug Testing and Analysis, EarlyView.Across 33 Anti‐Doping Organisations (ADOs), 85% reported experiencing at least one contamination‐claim case in 2024–2025, but only 36% operate a standardised process for handling such claims. Dietary supplements were the leading alleged contamination source (76% of ADOs), followed by food (42%) and pharmaceutical products, intimate contact, and other ...
Kristian Slíž +2 more
wiley +1 more source
PLoS ONE, 2016 Dehydroepiandrosterone sulfate (DHEAS) is a circulating sulfated steroid considered to be a pro-androgen in mammalian physiology. Here we show that at a physiological concentration (1 μM), DHEAS induces the phosphorylation of the kinase Erk1/2 and of the
Dimitrios Papadopoulos +4 more
doaj +1 more source
Clinical and Translational Science, 2021 Long‐term stress can lead to long‐term increased cortisol plasma levels, which increases the risk of numerous diseases. Dehydroepiandrosterone (DHEA) and its sulfated form dehydroepiandrosterone‐sulfate (DHEAS), together DHEA(S), have shown to counteract
Maja Arena Jørgensen +3 more
doaj +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective Maternal obesity and excess gestational weight gain (GWG) are linked to adverse perinatal outcomes, potentially via disruption of the maternal–fetal stress axis. Placental HSD11B2 protects the fetus from excess glucocorticoids and may influence fetal programming during maternal metabolic stress.
Thorsten Braun +13 more
wiley +1 more source
, 2014 What is the role of myostatin and its relationship with obesity, androgens and follistatin levels in women with polycystic ovary syndrome (PCOS)? The myostatin level was positively correlated to the risk of abdominal obesity, but negatively associated ...
楊友仕 ;陳美州 ;楊政憲 ;楊偉勛 ;何弘能 +1 more
core +1 more source
Pulmonary Therapy, 2019 Introduction Among individuals with severe asthma, FEV1 is low in individuals with low dehydroepiandrosterone (DHEA) sulfate (DHEAS) levels. In the Severe Asthma Research Program (SARP), no women with DHEAS > 200 μg/dL had an FEV1 60% predicted received
Nadzeya Marozkina +6 more
doaj +1 more source
Theriogenology Wild, 2023 Dehydroepiandrosterone (DHEA) and its sulfate (DHEAS) are important estrogen precursors, secreted mainly by the adrenal cortex. At late gestation, both DHEA and DHEAS (DHEA(S)) are produced at high concentrations in some species due to the developing ...
Emilee N. Hart +2 more
doaj +1 more source