Results 11 to 20 of about 326,550 (210)

Urinary excretion of RAS, BMP, and WNT pathway components in diabetic kidney disease [PDF]

open access: gold, 2014
The renin-angiotensin system (RAS), bone morphogenetic protein (BMP), and WNT pathways are involved in pathogenesis of diabetic kidney disease (DKD).
Maryam Afkarian   +5 more
openalex   +4 more sources

Renal biopsy in diabetic patients: Histopathological and clinical correlations [PDF]

open access: yesRevista Portuguesa de Nefrologia e Hipertensão, 2021
Introduction: Diabetes is the leading cause of chronic kidney disease and end-stage kidney disease worldwide. A kidney biopsy in a diabetic patient must be considered when non-diabetic renal disease is suspected, such as in the presence of a rapid ...
Joana Paixão   +10 more
doaj   +1 more source

Metabolic phenotypes and risk of end-stage kidney disease in patients with type 2 diabetes

open access: yesFrontiers in Endocrinology, 2023
BackgroundObesity often initiates or coexists with metabolic abnormalities. This study aimed to investigate the pathological characteristics and the independent or mutual relations of obesity and metabolic abnormalities with end-stage kidney disease ...
Lijun Zhao   +12 more
doaj   +1 more source

Intravitreal vascular endothelial growth factor inhibitors did not increase the risk of end-stage renal disease in patients with biopsy-proven diabetic kidney disease based on matched study

open access: yesFrontiers in Pharmacology, 2022
Purpose: This study aimed to investigate the effects of intravitreal (IVT) VEGFi on long-term renal outcomes in patients with biopsy-proven diabetic kidney disease (DKD).Patients and methods: Patients prescribed IVT VEGFi (VEGFi group) were enrolled from
Xiang Xiao   +19 more
doaj   +1 more source

Urinary MicroRNA Profiling in the Nephropathy of Type 1 Diabetes [PDF]

open access: yes, 2013
Background: Patients with Type 1 Diabetes (T1D) are particularly vulnerable to development of Diabetic nephropathy (DN) leading to End Stage Renal Disease.
A Krupa   +67 more
core   +10 more sources

Research progress of single nucleotide polymorphisms and immune cells in diabetic kidney disease [PDF]

open access: yesJichu yixue yu linchuang, 2022
Diabetic kidney disease has obvious family aggregation and ethnic differences, some single nucleotide polymorphisms (SNPs) related to the susceptibility of diabetic kidney disease have been identified, especially engulfment and cell motility 1 (ELMO1 ...
GUO Meng-ran, MIN Hang, YE Yue, XU Xiao-shuang, ZHEN Dong-hu
doaj   +1 more source

Lower bile acids as an independent risk factor for renal outcomes in patients with type 2 diabetes mellitus and biopsy-proven diabetic kidney disease

open access: yesFrontiers in Endocrinology, 2022
AimsAbnormalities of glucolipid metabolism are critical mechanisms involved in the progression of diabetic kidney disease (DKD). Bile acids have an essential role in regulating glucolipid metabolism.
Xiang Xiao   +18 more
doaj   +1 more source

Exploring molecular targets in diabetic kidney disease [PDF]

open access: yesKidney Research and Clinical Practice, 2022
Diabetic kidney disease is the leading cause of end-stage kidney disease, and it remains a major challenge. Many factors, such as glomerular hyperfiltration, oxidative stress, inflammation, hypoxia, and epigenetics, are associated with the progression of
Sayako Maruno   +2 more
doaj   +1 more source

Association between serum uric acid and renal outcome in patients with biopsy-confirmed diabetic nephropathy

open access: yesEndocrine Connections, 2021
Objective: To investigate the relationship between serum uric acid (SUA) level and renal outcome in patients with type 2 diabetes mellitus (T2DM) and diabetic nephropathy (DN). Methods: A total of 393 Chinese patients with T2DM and biopsy-proven DN and
Yutong Zou   +16 more
doaj   +1 more source

New Diabetes Therapies and Diabetic Kidney Disease Progression:the Role of SGLT-2 Inhibitors [PDF]

open access: yes, 2018
Purpose of Review Sodium-glucose co-transporter 2 (SGLT-2) inhibitors have emerged as a promising drug class for the treatment of diabetic kidney disease.
Dekkers, Claire C. J.   +2 more
core   +5 more sources

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