Research progress on ferroptosis in diabetic kidney disease
Frontiers in Endocrinology, 2022 Ferroptosis is a newly discovered form of cell death that differs from other forms of regulated cell death at morphological, biochemical, and genetic levels, and is characterized by iron-dependent accumulation of lipid peroxides.
You Wu, Yan Chen
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Urinary excretion of RAS, BMP, and WNT pathway components in diabetic kidney disease. [PDF]
, 2014 The renin-angiotensin system (RAS), bone morphogenetic protein (BMP), and WNT pathways are involved in pathogenesis of diabetic kidney disease (DKD).
Afkarian, Maryam +5 more
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Cells, 2021 Diabetic kidney disease (DKD) is a frequent, potentially devastating complication of diabetes mellitus. Several factors are involved in its pathophysiology.
Claudio D. Gonzalez +4 more
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Urinary peptidomics analysis reveals proteases involved in diabetic nephropathy [PDF]
, 2017 Mechanisms underlying the onset and progression of nephropathy in diabetic patients are not fully elucidated. Deregulation of proteolytic systems is a known path leading to disease manifestation, therefore we hypothesized that proteases aberrantly ...
Bascands, Jean-Loup +15 more
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Advanced-Glycation End-Products Induce Podocyte Injury and Contribute to Proteinuria
Frontiers in Medicine, 2021 The prevalence of diabetes reaches epidemic proportions. Diabetes is the leading cause of end-stage kidney disease (ESKD) since 30–40% of diabetic patients develop diabetic nephropathy.
Rajkishor Nishad +6 more
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Elevated hemoglobin glycation index identify non-diabetic individuals at increased risk of kidney dysfunction [PDF]
, 2017 Hemoglobin glycation index (HGI), calculated as the difference between the observed value of HbA1 and the predicted HbA1c based on plasma glucose concentration, is a measure of the individual tendency toward non-enzymatic hemoglobin glycation which has ...
Andreozzi, F +6 more
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Diabetic kidney disease. new clinical and therapeutic issues. Joint position statement of the Italian Diabetes Society and the Italian Society of Nephrology on "the natural history of diabetic kidney disease and treatment of hyperglycemia in patients with type 2 diabetes and impaired renal function" [PDF]
, 2019 Recent epidemiological studies have disclosed heterogeneity in diabetic kidney disease (DKD). In addition to the classical albuminuric phenotype, two new phenotypes have emerged, i.e., “nonalbuminuric renal impairment” and “progressive renal decline ...
Barutta, Federica +7 more
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Use of Readily Accessible Inflammatory Markers to Predict Diabetic Kidney Disease
Frontiers in Endocrinology, 2018 Diabetic kidney disease is a common complication of type 1 and type 2 diabetes and is the primary cause of end-stage renal disease in developed countries. Early detection of diabetic kidney disease will facilitate early intervention aimed at reducing the
Lauren Winter +11 more
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CXCL16 and oxLDL are induced in the onset of diabetic nephropathy [PDF]
, 2009 Diabetic nephropathy (DN) is a major cause of end-stage renal failure worldwide. Oxidative stress has been reported to be a major culprit of the disease and increased oxidized low density lipoprotein (oxLDL) immune complexes were found in patients with ...
Abdel-Aziz, Abdel-Aziz H. +11 more
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Association Between Blood Pressure and Adverse Renal Events in Type 1 Diabetes. [PDF]
, 2016 ObjectiveTo compare different blood pressure (BP) levels in their association with the risk of renal outcomes in type 1 diabetes and to determine whether an intensive glycemic control strategy modifies this association.Research design and methodsWe ...
Gitelman, Stephen E +5 more
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