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Explainable machine learning-based prediction model for diabetic nephropathy [PDF]
The aim of this study is to analyze the effect of serum metabolites on diabetic nephropathy (DN) and predict the prevalence of DN through a machine learning approach. The dataset consists of 548 patients from April 2018 to April 2019 in Second Affiliated Hospital of Dalian Medical University (SAHDMU).
arxiv
Effects of antihypertensive drugs in experimental type 2 diabetes-related nephropathy [PDF]
Effects of antihypertensive drugs in experimental type 2 diabetes-related nephropathy.BackgroundIt has been extensively reported that antihypertensive drugs reduce proteinuria and glomerulosclerosis (GS) in many experimental nephropathies and in humans ...
Blanco, Sandra+4 more
core +1 more source
Proteinuria in Primary and Secondary Renal Diseases [PDF]
Proteinuria is a strong indicator of kidney disease. Various pathological conditions such as diabetes mellitus, cardiovascular disease and hypertension have been shown to provoke secondary kidney problems and significant proteinuria.
Anuradha B. Patil+2 more
doaj
BACKGROUND Studies have reported "dysbiotic" changes to gut microbiota, such as depletion of gut bacteria that produce short-chain fatty acids (SCFAs) through gut fermentation of fiber, in CKD and diabetes.
Y. Li+11 more
semanticscholar +1 more source
The Association Between Smoking Tobacco After a Diagnosis of Diabetes and the Prevalence of Diabetic Nephropathy in the Korean Male Population [PDF]
Objectives: Smoking is known to be associated with nephropathy in patients with diabetes. The distinct effects of smoking before and after diabetes has been diagnosed, however, are not well characterized. We evaluated the association of cigarette smoking
Hyungseon Yeom+3 more
doaj +1 more source
Ischemic renal diseases: New insights into old entities [PDF]
Ischemic renal diseases: New insights into old entities. Vascular nephropathies are a steadily increasing cause of end-stage renal failure. Arterionephrosclerosis and arteriolonephrosclerosis are common features in the hypertensive patient.
Hill, Gary S.+2 more
core +1 more source
Sarcopenia in diabetic nephropathy: a cross-sectional study
Objective. To investigate the relationship between sarcopenia and diabetic nephropathy.
Çeliker Meral+2 more
doaj +1 more source
Pathology identifies glomerular treatment targets in diabetic nephropathy
The development of the glomerular injury in diabetic nephropathy involves interactions between podocytes, endothelium, and the mesangium. Loss of podocytes is an early and critical step in the development of diabetic nephropathy, and analysis of ...
Charles E. Alpers, Kelly L. Hudkins
doaj +1 more source
Urinary transferrin as an early biomarker of diabetic nephropathy [PDF]
Background/Aim. Diabetic nephropathy is one of the leading cause of chronic kidney disease and end-stage renal disease. It occurs in 20%–40% of patients with diabetes mellitus and microalbuminuria is still considered as the first sign of diabetic ...
Terzić Brankica+9 more
doaj +1 more source
Macrophage Phenotype and Fibrosis in Diabetic Nephropathy
Diabetic nephropathy (DN) is the leading cause of end-stage renal disease globally. The primary initiating mechanism in DN is hyperglycemia-induced vascular dysfunction, but its progression is due to different pathological mechanisms, including oxidative
Priscila Calle, G. Hotter
semanticscholar +1 more source