Results 71 to 80 of about 34,166 (308)

Sodium Glucose Cotransporter-2 Inhibitors in Non-Diabetic Kidney Disease: Evidence in Experimental Models

open access: yesPharmaceuticals
Sodium glucose cotransporter 2 (SGLT2) inhibitors are a class of glucose-lowering agents widely used for the treatment of type 2 diabetes mellitus. A number of clinical trials in type 2 diabetic patients with different degrees of renal impairment have ...
Giovanna Castoldi   +7 more
doaj   +1 more source

Efficacy and Safety of Dotinurad Versus Febuxostat for the Treatment of Gout: A Randomized, Multicenter, Double‐Blind, Phase 3 Trial in China

open access: yesArthritis &Rheumatology, EarlyView.
Objective Dotinurad is a selective urate reabsorption inhibitor that reduces serum urate levels. We compared the efficacy and safety of dotinurad with febuxostat in Chinese patients with gout. Methods This phase 3, multicenter, randomized, double‐blind, parallel‐group study randomly allocated (1:1) eligible patients with gout to receive oral dotinurad ...
Jia Sun   +19 more
wiley   +1 more source

The Relationship Between Aldose Reductase and Isoxazole Derivatives: An In Vitro and In Silico Approach to Its Correlation With Diabetic Conditions

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Diabetes mellitus (DM), which can result in a number of problems such as cataracts, neuropathy, retinopathy, nephropathy, and several cardiovascular illnesses, continues to be a growing issue despite major advancements in treatment approaches.
Ahmet Esat Göner, Hatice Esra Duran
wiley   +1 more source

Diabetic nephropathy

open access: yesDisease-a-Month, 1998
Diabetic nephropathy is the most common cause of end-stage renal disease (ESRD) and accounts for 35% of the ESRD population in the United States. It results in considerable morbidity, mortality, and expense. The average cost of managing one diabetic patient with ESRD is approximately $50,000 a year.
openaire   +2 more sources

Cost–benefit analysis of screening programme for diabetic retinopathy in Bulgaria

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Late‐diagnosed diabetic retinopathy (DR) is difficult and expensive to treat. Screening programmes can identify the disease early and reduce the costs of its future treatment. This study aims to analyse the cost–benefit of screening programmes for DR.
Iva Nenkova   +5 more
wiley   +1 more source

Diabetic Nephropathy [PDF]

open access: yesClinical Medicine, 2012
Vujičić, Božidar   +4 more
openaire   +7 more sources

Coexistence of type 1 diabetes mellitus and minimal change disease in a 9-year-old girl. A case report

open access: yesPediatria i Medycyna Rodzinna, 2018
Type 1 diabetes mellitus is the most common metabolic disease in childhood, which may, after years, lead to late vascular complications, including diabetic kidney disease.
Konstancja Fornalczyk   +6 more
doaj   +1 more source

Effect of febuxostat on renal function in patients from South China with CKD3 diabetic nephropathy

open access: yesBrazilian Journal of Nephrology, 2020
Objective: To investigate the efficacy and safety of febuxostat on renal function in CKD stage 3 diabetic nephropathy patients. Methods: Patients in our hospital with chronic kidney disease (CKD) stage 3 diabetic nephropathy (DN) complicated by high ...
Huang Wen   +4 more
doaj   +2 more sources

DES‐Promoted Synthesis of 3,4‐Dihydropyrimidinones and Their Antidiabetic and Antioxidant Evaluation Supported With Computational Studies

open access: yesChemistry &Biodiversity, EarlyView.
DES‐promoted synthesis and antidiabetic evaluation of 3,4‐dihydropyrimidinones and their complementation with computational studies are reported. ABSTRACT A series of 3,4‐dihydropyrimidinone (DHPM) derivatives was synthesized using a green deep eutectic solvent (DES) system composed of ZnCl2 and urea, which acted simultaneously as solvent, catalyst ...
Gobind Kumar   +10 more
wiley   +1 more source

Procedural Characteristics and Safety of Slender Percutaneous Coronary Intervention: Slender Is Better

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Objectives We aimed to examine the procedural characteristics and safety profile of slender percutaneous coronary interventions (PCI) using a 5 Fr or smaller sheath. Background Smaller catheter size has been associated with fewer complications in PCI.
Fuminobu Yoshimachi   +11 more
wiley   +1 more source

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