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Progression of diabetic nephropathy [PDF]
Diabetic nephropathy is a major cause of renal failure. The decline in glomerular filtration rate (GFR) is highly variable, ranging from 2 to 20, with a median of 12 mL/min/year. The risk factors of losing filtration power (progression promoters) have not been clearly identified.
Peter Rossing+4 more
openaire +3 more sources
The care of the elderly with diabetic nephropathy in conservative treatment [PDF]
This study aimed to describe the care of the elderly and the participation of the family in the conservative treatment of diabetic nephropathy. This is a qualitative, descriptive and exploratory study developed with twelve people, from which six were ...
Caren da Silva Jacobi+5 more
doaj
The role of sirolimus in proteinuria in diabetic nephropathy rats [PDF]
Objective(s): The aim of this study was to observe the impact of sirolimus on proteinuria in streptozotocin (STZ) induced diabetic rats. Materials and Methods: Rats were given a single injection of STZ to induce diabetic rat model.
JinJun Wang+5 more
doaj +1 more source
Early Stage Diabetes Prediction via Extreme Learning Machine [PDF]
Diabetes is one of the chronic diseases that has been discovered for decades. However, several cases are diagnosed in their late stages. Every one in eleven of the world's adult population has diabetes. Forty-six percent of people with diabetes have not been diagnosed.
arxiv
Canopy FGF signaling regulator 2 (CNPY2) which is contributed to ERS is upregulated in the renal tubules of patients with diabetic nephropathy (DN). Mechanistically, CNPY2 may regulate ferroptosis and MAM integrity in renal tubular epithelial cells through PERK/ATF4/CHAC1 pathway, thereby promoting the progression of DN.
Jingfang Chen+9 more
wiley +1 more source
Protein kinase R-like endoplasmic reticulum kinase pathway and diabetic kidney disease
Endoplasmic reticulum stress is closely related to the occurrence and development of diabetic kidney disease.As an important signaling pathway induced by endoplasmic reticulum stress,protein kinase R-like endoplasmic reticulum kinase(PERK)pathway can ...
庞欣欣+5 more
doaj
The FGF13 level is significantly downregulated in premature aging murine hearts subject to D‐galactose and Doxorubicin. FGF13 overexpression and deficiency exacerbated and alleviated Doxorubicin/D‐galactose‐induced myocardial aging characteristics and functional impairment, respectively.
Enzhao Shen+15 more
wiley +1 more source
Angiopoietins and diabetic nephropathy [PDF]
Diabetic nephropathy is the main cause of end-stage renal failure in the Western world. In diabetes, metabolic and haemodynamic perturbations disrupt the integrity of the glomerular filtration barrier, leading to ultrastructural alterations of the glomeruli, including podocyte foot process fusion and detachment, glomerular basement membrane thickening,
openaire +6 more sources
FABP1 and FABP2 as markers of diabetic nephropathy
Background: Diabetes mellitus is the leading cause of diabetic nephropathy and a major public health issue worldwide. Approximately 20-30% of patients with type 2 diabetes mellitus (T2DM) have renal impairment.
I-Ting Tsai+10 more
semanticscholar +1 more source
A Touch Enabled Hemodynamic and Metabolic Monitor
This work presents a touch‐based hybrid platform for simultaneous monitoring of vital signs and sweat metabolites. With a simple tri‐finger touch of 4–6 min, users can concurrently get to know their glucose, uric acid, cortisol levels from fingertip sweat, along with blood pressure and heart rate.
Omeed Djassemi+19 more
wiley +1 more source