Results 271 to 280 of about 109,708 (338)

Isotopologue Ratios Identify 13C‐Depleted Biomarkers in Environmental Samples Impacted by Methane Turnover

open access: yesRapid Communications in Mass Spectrometry, Volume 39, Issue 22, 30 November 2025.
ABSTRACT Rationale The stable carbon isotopic composition (δ13C) of individual lipids is of great value in studying carbon cycling. Among those, microbial lipids in sediments impacted by high methane turnover stand out due to their uniquely depleted isotopic fingerprint.
Janina Groninga   +3 more
wiley   +1 more source

Gut Microbiota‐Derived Metabolites Orchestrate Metabolic Reprogramming in Diabetic Cardiomyopathy: Mechanisms and Therapeutic Frontiers

open access: yesThe FASEB Journal, Volume 39, Issue 17, 15 September 2025.
Schematic representation of how gut microbiota‐derived metabolites—such as SCFAs, TMAO, and tryptophan derivatives—modulate cardiac energy metabolism, inflammation, and epigenetic regulation, contributing to the pathogenesis of diabetic cardiomyopathy. Therapeutic strategies targeting the gut–heart axis hold translational promise for metabolic cardiac ...
Jing‐yu Jin   +12 more
wiley   +1 more source

Designing New Natural‐Mimetic Phosphatidic Acid: A Versatile and Innovative Synthetic Strategy for Glycerophospholipid Research

open access: yesAngewandte Chemie, Volume 137, Issue 36, September 1, 2025.
We report the role of the fatty acyl chains in biological activities of phosphatidic acids (PA). Several PA probes having two different fatty acyl chains were synthesized through a multi‐steps synthesis and bearing various fluorophores or photo‐cross‐linkers (PCL).
Antoine Schlichter   +29 more
wiley   +2 more sources

Limited Diversity of Thermal Adaptation to a Critical Temperature in <i>Zymomonas mobilis</i>: Evidence from Multiple-Parallel Laboratory Evolution Experiments. [PDF]

open access: yesInt J Mol Sci
Pattanakittivorakul S   +9 more
europepmc   +1 more source

The Non‐Coding Regulatory Variant rs2863002 at chr11p11.2 Increases Neuroblastoma Risk by Affecting HSD17B12 Expression and Lipid Metabolism

open access: yesAdvanced Science, Volume 12, Issue 33, September 4, 2025.
The SNP rs2863002 at the 11p11.2 locus, identified through GWAS, is associated with an increased risk of neuroblastoma. The rs2863002‐C allele impairs the binding of the transcription factor GATA3, resulting in upregulation of the HSD17B12 gene.
Teresa Maiorino   +20 more
wiley   +1 more source

Red Blood Cell Membrane Lipidomics: Potential Biomarkers Detecting Method for Plasma Volume Overload and Major Adverse Cardiovascular Events in Chronic Heart Failure Patients

open access: yesAdvanced Science, Volume 12, Issue 33, September 4, 2025.
A novel RBC indicator, ESI, is better than the traditional RBC indicators and is associated with CHF prevalence and in‐hospital death. RBC membrane lipidomics, Cer 18:0;O2/16:0, and LPE 18:0, are associated with plasma volume overload and MACE in CHF patients, but these plasma lipids could not.
Lin Zhang   +12 more
wiley   +1 more source

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