Differential Signaling During Macropinocytosis in Response to M-CSF and PMA in Macrophages
The cellular movements that construct a macropinosome have a corresponding sequence of chemical transitions in the cup-shaped region of plasma membrane that becomes the macropinosome.
Sei eYoshida+6 more
doaj +1 more source
Novozym® 435, an immobilized lipase from Candida antarctica B. (CALB), was used as a biocatalyst for the synthesis of high purity medium chain diacylglycerol (MCD) in a bubble column reactor.
Jiazi Chen+5 more
doaj +1 more source
Diacylglycerol oil for the metabolic syndrome [PDF]
Excess adiposity has been shown to play a crucial role in the development of the metabolic syndrome. The elevated fasting and postprandial triglyceride-rich lipoprotein levels is the central lipid abnormality observed in the metabolic syndrome.
Norio Tada+5 more
openaire +4 more sources
Phosphatidylinositol (4,5)-bisphosphate turnover by INP51 regulates the cell wall integrity pathway in "Saccharomyces cerevisiae" [PDF]
Signal transduction pathways are important for the cell to transduce external or internal stimuli where second messengers play an important role as mediators of the stimuli. One important group of second messengers are the phosphoinositide family present
Morales-Johansson, Helena
core +2 more sources
Human Brain Lipidomics: Investigation of Formalin Fixed Brains
Human brain lipidomics have elucidated structural lipids and lipid signal transduction pathways in neurologic diseases. Such studies have traditionally sourced tissue exclusively from brain bank biorepositories, however, limited inventories signal that ...
Aaron W. Beger+5 more
doaj +1 more source
Intrinsic up-regulation of 2-AG favors an area specific neuronal survival in different in vitro models of neuronal damage [PDF]
BACKGROUND: The endocannabinoid 2-arachidonoyl glycerol (2-AG) acts as a retrograde messenger and modulates synaptic signaling e. g. in the hippocampus. 2-AG also exerts neuroprotective effects under pathological situations.
Bechmann, Ingo Jürgen+8 more
core +3 more sources
DAG tales: the multiple faces of diacylglycerol—stereochemistry, metabolism, and signaling
The neutral lipids diacylglycerols (DAGs) are involved in a plethora of metabolic pathways. They function as components of cellular membranes, as building blocks for glycero(phospho)lipids, and as lipid second messengers.
Thomas O. Eichmann, A. Lass
semanticscholar +1 more source
Regulation of Signaling and Metabolism by Lipin-mediated Phosphatidic Acid Phosphohydrolase Activity
Phosphatidic acid (PA) is a glycerophospholipid intermediate in the triglyceride synthesis pathway that has incredibly important structural functions as a component of cell membranes and dynamic effects on intracellular and intercellular signaling ...
Andrew J. Lutkewitte, Brian N. Finck
doaj +1 more source
Significance Lipid transmitters, such as endocannabinoid and eicosanoids, play important roles in the nervous system and regulate behaviors that include pain, emotionality, and addiction.
Daisuke Ogasawara+19 more
semanticscholar +1 more source
Modification of Lipid Bilayer Structure by Diacylglycerol: A Comparative Study of Diacylglycerol and Cholesterol [PDF]
Diacylglycerols (DAGs) are important second messengers in biomembranes, and they can activate protein kinase C and many other enzymes and receptors. However, their interactions with cholesterol and other lipids have not been previously studied using molecular dynamics (MD) simulation.
Jian Dai+2 more
openaire +3 more sources