Results 31 to 40 of about 59,986 (162)
Human Brain Lipidomics: Investigation of Formalin Fixed Brains
Frontiers in Molecular Neuroscience, 2022 Human brain lipidomics have elucidated structural lipids and lipid signal transduction pathways in neurologic diseases. Such studies have traditionally sourced tissue exclusively from brain bank biorepositories, however, limited inventories signal that ...
Aaron W. Beger +5 more
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Diacylglycerol kinase ζ controls diacylglycerol metabolism at the immunological synapse
Molecular Biology of the Cell, 2011 Diacylglycerol (DAG) generation at the T cell immunological synapse (IS) determines the correct activation of antigen-specific immune responses. DAG kinases (DGKs) α and ζ act as negative regulators of DAG-mediated signals by catalyzing DAG conversion to phosphatidic acid (PA). Nonetheless, the specific input of each enzyme and their spatial regulation
Gharbi, Severine I. +7 more
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eLife, 2013 The crystal structure of a nucleotide exchange factor in white blood cells reveals an autoinhibitory mechanism that reinforces the switch-like behaviour of the signalling protein Ras.
Christopher Hein +2 more
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FoodsMyofibrillar protein–diacylglycerol emulsions containing catechin (MP-DAG-C) possess outstanding emulsifying property and oxidative stability. However, the effect of pH on MP-DAG-C emulsions should be revealed to provide possibilities for their ...
Yuexin Li +6 more
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European Journal of Histochemistry, 2009 DAG, 1,2-diacylglycerol; EGF, epidermal growth factor; TNF, tumour necrosis factor; IGF-I, insulinlike growth factor I; Ins(n)P, inositol phosphate; Ins(n,n)P2, inositol bisphosphate; Ins(n,n,n)P3, inositol trisphosphate; MEL, murine erythroleukemia ...
C D'Santos +4 more
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Activation Mechanisms and Diverse Functions of Mammalian Phospholipase C
Biomolecules, 2023 Phospholipase C (PLC) plays pivotal roles in regulating various cellular functions by metabolizing phosphatidylinositol 4,5-bisphosphate in the plasma membrane. This process generates two second messengers, inositol 1,4,5-trisphosphate and diacylglycerol,
Kaori Kanemaru, Yoshikazu Nakamura
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Evidence for regulated monoacylglycerol acyltransferase expression and activity in human liver
Journal of Lipid Research, 2012 Intrahepatic lipid accumulation is extremely common in obese subjects and is associated with the development of insulin resistance and diabetes. Hepatic diacylglycerol and triacylglycerol synthesis predominantly occurs through acylation of glycerol-3 ...
Angela M. Hall +11 more
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The Impact of Rice Lipid on In Vitro Rice Starch Digestibility
Foods, 2022 The negative role of lipids in rice starch digestion is well-known; however, the effect of individual native lipids on starch digestibility has not been studied.
Amina Khatun +2 more
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Journal of Lipid Research, 2019 In mammals, lipids are selectively transported to specific sites using multiple classes of lipoproteins. However, in Drosophila, a single class of lipoproteins, lipophorin, carries more than 95% of the lipids in the hemolymph.
Naoya Matsuo +6 more
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A molecular mechanism for diacylglycerol-mediated promotion of negative caloric balance
Diabetes, Metabolic Syndrome and Obesity, 2009 Hidekatsu Yanai1,2, Yoshiharu Tomono3, Kumie Ito1,2, Yuji Hirowatari4, Hiroshi Yoshida1,5, Norio Tada1,21Department of Internal Medicine, 2Institute of Clinical Medicine and Research, 3Department of Nutrition, 5Department of Laboratory Medicine, Jikei ...
Yanai H
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