Results 11 to 20 of about 59,986 (162)

The role of diacylglycerol in the exocytosis of the sperm acrosome. Studies using diacylglycerol lipase and diacylglycerol kinase inhibitors and exogenous diacylglycerols [PDF]

open access: yesBiochemical Journal, 1992
When ram spermatozoa were treated with Ca2+ and the ionophore A23187 to induce acrosomal exocytosis, a rise in diacylglycerol (DAG) mass was observed, concomitant with a rapid breakdown of [32P]P1-labelled phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 4-phosphate and a rise in [32P]Pi-labelled phosphatidate. Inclusion of the DAG lipase
E R, Roldan, R A, Harrison
openaire   +2 more sources

Diacylglycerol kinase η1 is a high affinity isozyme for diacylglycerol [PDF]

open access: yesFEBS Letters, 2015
Diacylglycerol kinase (DGK) η plays important roles in various patho‐physiological events such as oncogenesis. In this study, we performed an enzymological characterization of DGKη splice variant 1 (DGKη1). The K m value for diacylglycerol was 0.14 mol%.
Komenoi, Suguru   +3 more
openaire   +2 more sources

Engineering the Thermostability of the Mono- and Diacylglycerol Lipase SMG1 for the Synthesis of Diacylglycerols

open access: yesFoods, 2022
Diacylglycerols (DAGs) display huge application prospectives in food industries. Therefore, new strategies to produce diacylglycerides are needed. Malassezia globose lipase (SMG1) could be used to synthesize DAGs. However, the poor thermostability of SMG1 seriously hampers its application.
Lilang Li   +4 more
openaire   +3 more sources

Produção de monoacilgliceróis e diacilgliceróis via glicerólise enzimática e destilação molecular Production of monoglycerides and diglycerides through lipase-catalyzed glycerolysis and molecular distillation

open access: yesQuímica Nova, 2009
Monoacilglycerides and diacilglycerides are produced through lipase-catalyzed glycerolysis of soybean oil using Candida antarctica B in a solvent-free system.
Patricia Bogalhos Lucente Fregolente   +4 more
doaj   +1 more source

Differential Signaling During Macropinocytosis in Response to M-CSF and PMA in Macrophages

open access: yesFrontiers in Physiology, 2015
The cellular movements that construct a macropinosome have a corresponding sequence of chemical transitions in the cup-shaped region of plasma membrane that becomes the macropinosome.
Sei eYoshida   +6 more
doaj   +1 more source

Acid sphingomyelinase activity is regulated by membrane lipids and facilitates cholesterol transfer by NPC2[S]

open access: yesJournal of Lipid Research, 2014
During endocytosis, membrane components move to intraluminal vesicles of the endolysosomal compartment for digestion. At the late endosomes, cholesterol is sorted out mainly by two sterol-binding proteins, Niemann-Pick protein type C (NPC)1 and NPC2.
Vincent O. Oninla   +3 more
doaj   +1 more source

Fabrication of Concentrated Palm Olein-Based Diacylglycerol Oil–Soybean Oil Blend Oil-In-Water Emulsion: In-Depth Study of the Rheological Properties and Storage Stability

open access: yesFoods, 2020
The present study focused on investigating the storage stability of oil-in-water (O/W) emulsions with high oil volume fractions prepared with palm olein-based diacylglycerol oil (POL-DAG)/soybean oil (SBO) blends at 25 °C.
Siou Pei Ng   +9 more
doaj   +1 more source

Effects of Fish Oil and Grape Seed Extract Combination on Hepatic Endogenous Antioxidants and Bioactive Lipids in Diet-Induced Early Stages of Insulin Resistance in Rats

open access: yesMarine Drugs, 2020
Diacylglycerols (DAG) and ceramides have been suggested as early predictors of insulin resistance. This study was aimed to examine the combined effects of fish oil (FO) and grape seed extract (GSE) on hepatic endogenous antioxidants, DAG and ceramides in
Núria Taltavull   +7 more
doaj   +1 more source

A New Targeted Lipidomics Approach Reveals Lipid Droplets in Liver, Muscle and Heart as a Repository for Diacylglycerol and Ceramide Species in Non-Alcoholic Fatty Liver

open access: yesCells, 2019
Obesity is frequently associated with excessive accumulation of lipids in ectopic tissue and presents a major risk factor for type 2 diabetes (T2D) and non-alcoholic fatty liver disease (NAFLD). Diacylglycerols (DAGs) and ceramides (CERs) were identified
Christina Preuss   +7 more
doaj   +1 more source

Lipid activation of protein kinases

open access: yesJournal of Lipid Research, 2009
Lipids acutely control the amplitude, duration, and subcellular location of signaling by lipid second messenger-responsive kinases. Typically, this activation is controlled by membrane-targeting modules that allosterically control the function of kinase ...
Alexandra C. Newton
doaj   +1 more source

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