Results 71 to 80 of about 73,981 (291)

include unusual diacylglycerol lipase [PDF]

open access: yes, 2015
Phospholipids are well known for their membrane-forming properties and thereby delimit any cell from the exterior world. In addition, membrane phospholipids can act as precursors for signals and other biomolecules during their turnover.
Diana X. Sahonero‐Canavesi   +13 more
core   +1 more source

Lyssavirus Nucleoprotein Induces GPAT4‐Mediated CYB5R1 Depalmitoylation to Suppress Ferroptosis and Promote Viral Replication

open access: yesAdvanced Science, EarlyView.
Lipid metabolism plays a vital role in viral infections. Here, we reveal that the lyssavirus N protein regulates GPAT4 to induce lipid droplet biogenesis, restricting CYB5R1 palmitoylation and reducing ferroptosis susceptibility to ultimately promote viral replication.
Jianqing Zhao   +6 more
wiley   +1 more source

Nuclear inositides

open access: yesEuropean Journal of Histochemistry, 2009
DAG, 1,2-diacylglycerol; EGF, epidermal growth factor; TNF, tumour necrosis factor; IGF-I, insulinlike growth factor I; Ins(n)P, inositol phosphate; Ins(n,n)P2, inositol bisphosphate; Ins(n,n,n)P3, inositol trisphosphate; MEL, murine erythroleukemia ...
C D'Santos   +4 more
doaj   +1 more source

The Impact of Rice Lipid on In Vitro Rice Starch Digestibility

open access: yesFoods, 2022
The negative role of lipids in rice starch digestion is well-known; however, the effect of individual native lipids on starch digestibility has not been studied.
Amina Khatun   +2 more
doaj   +1 more source

Localized diacylglycerol-dependent stimulation of Ras and Rap1 during phagocytosis

open access: yes, 2023
We describe a role for diacylglycerol in the activation of Ras and Rap1 at the phagosomal membrane. During phagocytosis, Ras density was similar on the surface and invaginating areas of the membrane, but activation was detectable only in the latter and ...
Roberto Botelho (14518364)   +9 more
core   +1 more source

SPRED2 Negatively Regulates CD8+ T Cell‐Mediated Antitumor Immunity in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Sprouty‑related EVH1 domain containing 2 (SPRED2) restrains Ras/Raf/ERK signaling in CD8+ T cells. Host SPRED2 deficiency enhances T‐cell survival, cytotoxicity, and memory‐like phenotypes, reducing primary tumor growth and endpoint lung metastatic burden in breast cancer models.
Miao Tian   +8 more
wiley   +1 more source

Evidence for regulated monoacylglycerol acyltransferase expression and activity in human liver

open access: yesJournal of Lipid Research, 2012
Intrahepatic lipid accumulation is extremely common in obese subjects and is associated with the development of insulin resistance and diabetes. Hepatic diacylglycerol and triacylglycerol synthesis predominantly occurs through acylation of glycerol-3 ...
Angela M. Hall   +11 more
doaj   +1 more source

Epithelial SLC25A20 Deficiency Drives Immunosuppressive Neutrophil Remodeling via ARG1 Palmitoylation to Promote Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
SLC25A20 deficiency in tumor cells compromises mitochondrial LCFA transport, which suppresses FAO and drives compensatory release of palmitic acid‐enriched lipids into the TME. These tumor‐derived palmitic acids are taken up by TANs, promoting ZDHHC18‐catalyzed ARG1 palmitoylation.
Yue Han   +8 more
wiley   +1 more source

Ks1, an epithelial cell-specific gene, responds to early signals of head formation in Hydra [PDF]

open access: yes, 1994
As a molecular marker for head specification in Hydra, we have cloned an epithelial cell-specific gene which responds to early signals of head formation.
Weinziger, Ruth   +3 more
core   +1 more source

Diacylglycerol stimulates phospholipase A2 from Swiss 3T3 fibroblasts [PDF]

open access: yes, 1988
We recently demonstrated that diacylglycerol induced arachidonate release and prostaglandin E2 synthesis in 3T3 fibroblasts, and greatly augmented prostaglandin E2 synthesis in response to submaximal and maximal concentrations of bradykinin.
Ronald M. Burch, Burch, Ronald M.
core   +1 more source

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