Results 11 to 20 of about 373,653 (317)

Novel Diagnostic Biomarkers in Colorectal Cancer [PDF]

International Journal of Molecular Sciences, 2022
Colorectal cancer (CRC) is still a leading cause of cancer death worldwide. Less than half of cases are diagnosed when the cancer is locally advanced. CRC is a heterogenous disease associated with a number of genetic or somatic mutations. Diagnostic markers are used for risk stratification and early detection, which might prolong overall survival ...
Aneta L. Zygulska, Piotr Pierzchalski
openaire   +3 more sources

Selenium-Binding Protein 1 (SELENBP1) as Biomarker for Adverse Clinical Outcome After Traumatic Spinal Cord Injury

Frontiers in Neuroscience, 2021
Introduction: Traumatic spinal cord injury (TSCI) presents a diagnostic challenge as it may have dramatic consequences for the affected patient. Additional biomarkers are needed for improved care and personalized therapy.Objective: Serum selenium binding
Julian Seelig, Raban Arved Heller, Raban Arved Heller, Raban Arved Heller, Patrick Haubruck, Patrick Haubruck, Qian Sun, Georg Jochen Klingenberg, Julian Hackler, Helena Lucia Crowell, Helena Lucia Crowell, Volker Daniel, Arash Moghaddam, Lutz Schomburg, Bahram Biglari   +14 more
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Analysis of the Prognostic Value and Potential Molecular Mechanisms of TREM-1 Overexpression in Papillary Thyroid Cancer via Bioinformatics Methods

Frontiers in Endocrinology, 2021
BackgroundTriggering receptor expressed on myeloid cells-1 (TREM-1) has been reported as a biomarker in many cancers. However, the biological function of TREM-1 in papillary thyroid carcinoma (PTC) remains unknown.MethodsWe obtained TREM-1 expression ...
Zhenyu Xie, Xin Li, Yuzhen He, Song Wu, Shiyue Wang, Jianjian Sun, Yuchen He, Yu Lun, Shijie Xin, Jian Zhang   +9 more
doaj   +1 more source

Cancer Diagnostic and Predictive Biomarkers [PDF]

BioMed Research International, 2014
The new high-throughput “omics” technologies have recently opened the possibility to identify molecular changes and metabolic pathways in each cancer type with the possibility of molecular tumor subclassification and identification of a more reliable prognosis and appropriate treatment [1–3].
Franco M. Buonaguro, David Pauza, Maria Lina Tornesello, Pierre Hainaut, Renato Franco, Francesco M. Marincola   +5 more
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A Distinct Urinary Biomarker Pattern Characteristic of Female Fabry Patients That Mirrors Response to Enzyme Replacement Therapy [PDF]

, 2011
Female patients affected by Fabry disease, an X-linked lysosomal storage disorder, exhibit a wide spectrum of symptoms, which renders diagnosis, and treatment decisions challenging.
Breunig Frank, Wanner, Christoph, Hughes, D A, Warnock, D G, Derralynn A Hughes, Mullen, William, Andreas D. Kistler, Andreas D Kistler, Kistler Andreas D., Jeevaratnam, P, Serra, AL, Siwy, Justyna, Frank, Breunig, Derralynn A. Hughes, Scherl, A, Alexander Scherl, Mischak Harald, Mischak, H., Wüthrich, Rudolf P., Andreas L Serra, Jeevaratnam Praveen, Warnock, D.G., Kistler, A D, Jeevaratnam, P., Rudolf P. Wüthrich, Warnock, DG, Wüthrich Rudolf P., Wanner Christoph, Frank Breunig, Praveen Jeevaratnam, Justyna Siwy, Wüthrich, R P, Serra, A L, Serra Andreas L., Mischak, Harald, Hughes, DA, David G. Warnock, Breunig, F, Serra, Andreas L., Serra, A.L., Christoph Wanner, Jeevaratnam, Praveen, William Mullen, Kistler, AD, Scherl, A., Siwy, J., Hughes Derralynn A., Wanner, C., Mischak, H, Siwy Justyna, Warnock, David G., Andreas L. Serra, Scherl, Alexander, Wanner, C, Wüthrich, R.P., Kistler, Andreas D., Mullen, W., Breunig, F., Siwy, J, Hughes, Derralynn A., Wuthrich, RP, Mullen William, Kistler, A.D., Harald Mischak, Hughes, D.A., Scherl Alexander, David G Warnock, Rudolf P Wüthrich, Warnock David G., Mullen, W   +69 more
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Clinical Relevance of Soluble Forms of Immune Checkpoint Molecules sPD-1, sPD-L1, and sCTLA-4 in the Diagnosis and Prognosis of Ovarian Cancer

Diagnostics, 2022
It is crucial to find new diagnostic and prognostic biomarkers. A total of 80 patients were enrolled in the study. The study group consisted of 37 patients with epithelial ovarian cancer, and the control group consisted of 43 patients with benign ovarian
Janina Świderska, Mateusz Kozłowski, Katarzyna Nowak, Małgorzata Rychlicka, Dorota Branecka-Woźniak, Sebastian Kwiatkowski, Ewa Pius-Sadowska, Bogusław Machaliński, Aneta Cymbaluk-Płoska   +8 more
doaj   +1 more source

MicroRNA as Biomarkers and Diagnostics

Journal of Cellular Physiology, 2015
MicroRNAs (miRNAs) are a group of small non‐coding RNAs that are involved in regulating a range of developmental and physiological processes; their dysregulation has been associated with development of diseases including cancer. Circulating miRNAs and exosomal miRNAs have also been proposed as being useful in diagnostics as biomarkers for diseases and ...
Jin, Wang, Jinyun, Chen, Subrata, Sen
openaire   +3 more sources

Diagnostic Potential of Salivary Biomarker Profiles in Epidemiological Survey of Periodontitis [PDF]

, 2020
Objective: To assess the diagnostic value of salivary biomarker profiles in determining the prevalence of periodontitis in the adult population using the case definition for population-based surveillance of periodontitis (CDC/AAP) criteria ...
Lona K. Mohammed, Sarhang S. Gul
core   +1 more source

MicroRNAs in Pulmonary Hypertension, from Pathogenesis to Diagnosis and Treatment

Biomolecules, 2022
Pulmonary hypertension (PH) is a fatal and untreatable disease, ultimately leading to right heart failure and eventually death. microRNAs are small, non-coding endogenous RNA molecules that can regulate gene expression and influence various biological ...
Junhua Xu, John Linneman, Yanfeng Zhong, Haoyang Yin, Qinyi Xia, Kang Kang, Deming Gou   +6 more
doaj   +1 more source

Validation of CDC45 as a novel biomarker for diagnosis and prognosis of gastric cancer [PDF]

PeerJ
Background Cell division cycle protein 45 (CDC45) has been demonstrated to play vital roles in the progression of various malignancies. However, the clinical significance of CDC45 in gastric cancer (GC) remains unreported.
Lihua Wu, Gan Gao, Hui Mi, Zhou Luo, Zheng Wang, Yongdong Liu, Liangyan Wu, Haihua Long, Yongqi Shen   +8 more
doaj   +2 more sources