Results 41 to 50 of about 373,653 (317)

Diagnostic Biomarker for Breast Cancer Applying Rayleigh Low-Rank Embedding Thermography

open access: yesEngineering Proceedings, 2023
Thermography has found extensive application as a supplementary diagnostic tool in breast cancer diagnosis, notably complementing the clinical breast exam (CBE). Within dynamic thermography, matrix factorization methods have demonstrated their utility in
Bardia Yousefi   +2 more
doaj   +1 more source

Elevated microRNA expression could be diagnostic biomarker for PDAC

open access: yes, 2020
Background: Pancreatic ductal adenocarcinoma (PDAC) is the most common type of PCa with 2-9% 5-year survival rate. PDAC is the most lethal malignancy worldwide and hence the molecular mechanisms, which are linked to the aggressive features, should be ...
Uysal Onganer, P.   +4 more
core   +1 more source

Diagnostic and prognostic biomarkers for HAND

open access: yesJournal of NeuroVirology, 2019
In 2007, the nosology for HIV-1-associated neurocognitive disorders (HAND) was updated to a primarily neurocognitive disorder. However, currently available diagnostic tools lack the sensitivity and specificity needed for an accurate diagnosis for HAND. Scientists and clinicians, therefore, have been on a quest for an innovative biomarker to diagnose (i.
Kristen A, McLaurin   +2 more
openaire   +3 more sources

FINDING DIAGNOSTIC BIOMARKERS IN PROTEOMIC SPECTRA [PDF]

open access: yesBiocomputing 2006, 2005
In seeking to find diagnostic biomarkers in proteomic spectra, two significant problems arise. First, not only is there noise in the measured intensity at each m/z value, but there is also noise in the measured m/z value itself. Second, the potential for overfitting is severe: it is easy to find features in the spectra that accurately discriminate ...
Pallavi N. Pratapa   +2 more
openaire   +3 more sources

Enhancing sepsis biomarker development: key considerations from public and private perspectives [PDF]

open access: yes
Implementation of biomarkers in sepsis and septic shock in emergency situations, remains highly challenging. This viewpoint arose from a public–private 3-day workshop aiming to facilitate the transition of sepsis biomarkers into clinical practice.
Rodriguez-Manzano, J   +21 more
core   +1 more source

Glucosylsphingosine Is a Highly Sensitive and Specific Biomarker for Primary Diagnostic and Follow-Up Monitoring in Gaucher Disease in a Non-Jewish, Caucasian Cohort of Gaucher Disease Patients

open access: yes, 2013
Gaucher disease (GD) is the most common lysosomal storage disorder (LSD). Based on a deficient β-glucocerebrosidase it leads to an accumulation of glucosylceramide. Standard diagnostic procedures include measurement of enzyme activity, genetic testing as
Rolfs, A   +59 more
core   +1 more source

Assessment of Glutathione Peroxidase-1 (GPX1) Gene Expression as a Specific Diagnostic and Prognostic Biomarker in Malignant Pleural Mesothelioma

open access: yesDiagnostics, 2021
Malignant pleural mesothelioma (MPM) is a malignant tumor of the mesothelial lining of the thorax. It has been related to frequent exposure to asbestos. Diagnosis of malignant pleural mesothelioma is considered a criticizing problem for clinicians. Early
Amal F. Gharib   +8 more
doaj   +1 more source

Omics biomarkers and early diagnostics [PDF]

open access: yesBiomeditsinskaya Khimiya, 2017
One of main goals for omics sciences, such as transcriptomics, proteomics and metabolomics, in medicine is biomarker discovery for diagnostics of common non-infectious diseases. The opinion paper discusses diagnostic parameters, which limit the use of the biomarkers, as well as a positive predictive value, and conditions providing possible ...
openaire   +2 more sources

Metabolic profiling framework for discovery of candidate diagnostic markers of malaria [PDF]

open access: yes, 2013
Despite immense efforts to combat malaria in tropical and sub-tropical regions, the potency of this vector-borne disease and its status as a major driver of morbidity and mortality remain undisputed.
Utzinger, Juerg   +8 more
core   +1 more source

A Diagnostic Biomarker for Cervical Myelopathy Based on Dynamic MRI. [PDF]

open access: yes, 2023
STUDY DESIGN Multicenter prospective observational study. OBJECTIVE Diffusion tensor imaging (DTI) in flexion-extension improves the diagnosis of degenerative cervical myelopathy (DCM).
Lukas Andereggen   +11 more
core   +1 more source

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