Results 61 to 70 of about 533,448 (310)

Flexible combination of multiple diagnostic biomarkers to improve diagnostic accuracy

, 2015
In medical research, it is common to collect information of multiple continuous biomarkers to improve the accuracy of diagnostic tests. Combining the measurements of these biomarkers into one single score is a popular practice to integrate the collected ...
Fang, Yixin, Rong, Alan, Wang, Junhui, Xu, Tu   +3 more
core   +1 more source

Non-coding RNAs in saliva: emerging biomarkers for molecular diagnostics. [PDF]

, 2015
Saliva is a complex body fluid that comprises secretions from the major and minor salivary glands, which are extensively supplied by blood. Therefore, molecules such as proteins, DNA, RNA, etc., present in plasma could be also present in saliva.
Majem, Blanca, Reventós, Jaume, Rigau, Marina, Wong, David T   +3 more
core   +4 more sources

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Association of Blood Biomarkers With Acute Sport-Related Concussion in Collegiate Athletes: Findings From the NCAA and Department of Defense CARE Consortium [PDF]

, 2020
Importance: There is potential scientific and clinical value in validation of objective biomarkers for sport-related concussion (SRC). Objective: To investigate the association of acute-phase blood biomarker levels with SRC in collegiate athletes.
Broglio, Steven P., Brooks, M. Alison, Cameron, Kenneth L., Campbell, Darren E., CARE Consortium Investigators, DiFiori, Jon, Duma, Stephan, Foroud, Tatiana, Gill, Jessica, Giza, Christopher C., Goldman, Joshua, Guskiewicz, Kevin, Harezlak, Jaroslaw, Houston, Megan N., Huber, Daniel L., Jackson, Jonathan C., Katz, Barry P., McAllister, Thomas W., McCrea, Michael, McGinty, Gerald, Meier, Timothy B., Mihalik, Jason, Nelson, Lindsay D., Pasquina, Paul, Rowson, Steven, Saykin, Andrew J., Svoboda, Steven J.   +26 more
core   +1 more source

Biomarkers and diagnostics in heart failure

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2013
Heart failure (HF) biomarkers have dramatically impacted the way HF patients are evaluated and managed. B-type natriuretic peptide (BNP) and N-terminal proBNP (NT-proBNP) are the gold standard biomarkers in determining the diagnosis and prognosis of HF, and studies on natriuretic peptide-guided HF management look promising.
Gaggin, Hanna K., Januzzi, James L.
openaire   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

DTI Histogram and Texture Features as Early Predictors of Post-Radiotherapy Cognitive Decline

Applied Sciences
Background: Radiotherapy for brain tumors can induce cognitive decline, yet most studies examine white matter (WM) damage six months post-treatment, overlooking early microstructural changes.
Jincheng Wang, Philip Kyeremeh Jnr Oppong, Maho Kitagawa, Hidefumi Aoyama, Shunsuke Onodera, Satoshi Terae, Khin Khin Tha   +6 more
doaj   +1 more source

Decision Criteria for Large Vessel Occlusion Using Transcranial Doppler Waveform Morphology

Frontiers in Neurology, 2018
Background: The current lack of effective tools for prehospital identification of Large Vessel Occlusion (LVO) represents a significant barrier to efficient triage of stroke patients and detriment to treatment efficacy.
Samuel G. Thorpe, Corey M. Thibeault, Nicolas Canac, Seth J. Wilk, Thomas Devlin, Robert B. Hamilton   +5 more
doaj   +1 more source

The potential of glycomics as prognostic biomarkers in liver disease and liver transplantation [PDF]

, 2019
The study of glycomics is a novel and fascinating approach for the development of biomarkers. It has become clear that in the field of liver disease specific glycomic patters are present in specific disease states, which has led to the development of ...
Callewaert, Nico, Geerts, Anja, Van Vlierberghe, Hans, Verhelst, Xavier   +3 more
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source