Results 31 to 40 of about 373,653 (317)

Circulating miRNAs Associated with Dysregulated Vascular and Trophoblast Function as Target-Based Diagnostic Biomarkers for Preeclampsia

open access: yesCells, 2020
Preeclampsia (PE) is a pregnancy-specific disorder associated with hypertension and proteinuria. Since there is no proven method to treat PE, early prediction and accurate diagnosis are essential for appropriate management of the disease.
Suji Kim   +9 more
doaj   +1 more source

Identifying Aging-Related Biomarkers and Immune Infiltration Features in Diabetic Nephropathy Using Integrative Bioinformatics Approaches and Machine-Learning Strategies

open access: yesBiomedicines, 2023
Background: Aging plays an essential role in the development of diabetic nephropathy (DN). This study aimed to identify and verify potential aging-related genes associated with DN using bioinformatics analysis.
Tao Liu, Xing-Xing Zhuang, Jia-Rong Gao
doaj   +1 more source

Accuracy of circulating adiponectin for predicting gestational diabetes : a systematic review and meta-analysis [PDF]

open access: yes, 2016
Aims/hypothesis Universal screening for gestational diabetes mellitus (GDM) has not been implemented, and this has had substantial clinical implications. Biomarker-directed targeted screening might be feasible.
Kelsey, Tom   +20 more
core   +1 more source

Promising Novel Biomarkers for Hepatocellular Carcinoma: Diagnostic and Prognostic Insights

open access: yesJournal of Hepatocellular Carcinoma, 2023
James Yu,1 Robin Park,1 Richard Kim2 1Division of Hematology and Medical Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA; 2Department of Gastrointestinal Oncology, H.
Yu J, Park R, Kim R
doaj  

The Roles of Exosomes in Metastasis of Sarcoma: From Biomarkers to Therapeutic Targets

open access: yesBiomolecules, 2023
Sarcoma is a heterogeneous group of mesenchymal neoplasms with a high rate of lung metastasis. The cellular mechanisms responsible for sarcoma metastasis remain poorly understood.
Linyun Tan, Yitian Wang, Xin Hu, Li Min
doaj   +1 more source

Determining cut-points for Alzheimer's disease biomarkers: statistical issues, methods and challenges. [PDF]

open access: yes, 2012
New proposed criteria for the clinical diagnosis of Alzheimer's disease increasingly incorporate biomarkers, most of which are normally measured on a continuous scale. Operationalizing such criteria thus requires continuous biomarkers to be dichotomized,
Skillbäck, Tobias,   +10 more
core   +1 more source

Diagnostic Biomarker Hsa_circ_0126218 and Functioning Prediction in Peripheral Blood Monocular Cells of Female Patients With Major Depressive Disorder

open access: yesFrontiers in Cell and Developmental Biology, 2021
IntroductionAlthough major depressive diroder (MDD) has brought huge burden and challenges to society globally, effective and accurate diagnoses and treatments remain inadequate.
Tianyi Bu   +13 more
doaj   +1 more source

Renal Tumors [PDF]

open access: yesAmerican Journal of Surgical Pathology, 2013
The International Society of Urological Pathology convened a consensus conference on renal cancer, preceded by an online survey, to address issues relating to the diagnosis and reporting of renal neoplasia. In this report, the role of biomarkers in the diagnosis and assessment of prognosis of renal tumors is addressed. In particular we focused upon the
Tan, Puay Hoon   +146 more
openaire   +7 more sources

Cerebrospinal Fluid Tau, p-Tau 181 and Amyloid-beta(38/40/42) in Frontotemporal Dementias and Primary Progressive Aphasias [PDF]

open access: yes, 2010
Background/Aims: We determined cerebrospinal fluid (CSF) concentrations of amyloid-beta(A beta)(1-38), A beta(1-40), A beta(1-42), total tau and phospho-tau (p-tau) in order to study their differential expression in frontotemporal dementia (FTD, n = 25 ...
Hermann Esselmann   +17 more
core   +1 more source

Molecular characterization of vaginal microbiota using a new 22-species qRT-PCR test to achieve a relative-abundance and species-based diagnosis of bacterial vaginosis

open access: yesFrontiers in Cellular and Infection Microbiology
BackgroundNumerous bacteria are involved in the etiology of bacterial vaginosis (BV). Yet, current tests only focus on a select few. We therefore designed a new test targeting 22 BV-relevant species.MethodsUsing 946 stored vaginal samples, a new qPCR ...
Ayodeji B. Oyenihi   +7 more
doaj   +1 more source

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