Prevalence of Genetic Diamine Oxidase (DAO) Deficiency in Female Patients with Fibromyalgia in Spain [PDF]
Biomedicines, 2023 Diamine oxidase (DAO) is an enzyme that metabolizes intestinal histamine. Single nucleotide polymorphisms (SNPs) of the Amine Oxidase Copper Containing 1 (AOC1) gene can lead to low enzymatic activity or functionality in histamine metabolism.
Gülşah Okutan +8 more
doaj +6 more sources
Serum diamine oxidase (DAO) activity as a diagnostic test for histamine intolerance [PDF]
Clinical and Translational Allergy, 2011 Background Histamine intolerance (HIT) is characterized by an imbalance between histamine intake and the capacity for histamine degradation. The main enzyme for metabolizing ingested histamine is diamine oxidase (DAO). Determining DAO activity in serum may be useful in diagnosing HIT.
Music Ema +4 more
doaj +4 more sources
Multivariate statistical optimization of the ultrasonic-assisted extraction of diamine oxidase (DAO) from pea sprout [PDF]
Ultrasonics SonochemistryPea sprouts can provide a plant-based alternative to the commonly used pork kidney as a source of diamine oxidase (DAO), an enzyme used as a dietary supplement to prevent symptoms of histamine intolerance.
M. Khanlar +3 more
doaj +4 more sources
Histamine intolerance caused by Diamine Oxidase (DAO) deficiency – case report
Journal of Pre-Clinical and Clinical Research, 2022 Histamine is a biogenic amine, which occurs naturally in the human body. Histamine can be metabolised with Diamine Oxidase (DAO) Enzyme. It is estimated that in 1% of people, as a result of an imbalance between the supply and degradation of histamine, a ...
Aleksandra Iwona Zimna +5 more
doaj +4 more sources
Standardization of a colorimetric technique for determination of enzymatic activity of diamine oxidase (DAO) and its application in patients with clinical diagnosis of histamine intolerance [PDF]
World Allergy Organization Journal, 2020 Background: Diamine Oxidase (DAO) has an essential role for degradation of exogenous histamine in the intestine; thus, histamine intolerance (HI) mainly has been correlated to a low concentration and/or activity of this enzyme. The objective of the study
Camila Beltrán-Ortiz +8 more
doaj +2 more sources
Mapping of the binding sites of human diamine oxidase (DAO) monoclonal antibodies. [PDF]
Inflamm Res, 2018 Recently we characterized five mouse monoclonal antibodies that allow the specific and sensitive detection of human diamine oxidase (DAO). To understand differences in binding characteristics and recognition of enzyme variants, we mapped the antibody binding sites.Fragments of human DAO were expressed as glutathione-S-transferase fusion proteins that ...
Schwelberger HG, Feurle J, Houen G.
europepmc +4 more sources
A case series of diamine oxidase deficiency misdiagnosed as anxiety or panic attacks in patients with tachycardia [PDF]
Indian Journal of PsychiatryBackground: Diamine oxidase (DAO) deficiency, a key marker of histamine intolerance (HIT), often mimics anxiety or panic disorders, leading to a misdiagnoses and delayed treatment.
Ilkay Keskinel
doaj +2 more sources
Low serum diamine oxidase (DAO) activity levels in patients with migraine. [PDF]
Journal of Physiology and Biochemistry, 2020 Histamine intolerance is a disorder in the homeostasis of histamine due to a reduced intestinal degradation of this amine, mainly caused by a deficiency in the enzyme diamine oxidase (DAO).
Comas Basté, Oriol +6 more
core +4 more sources
Effect of diamine oxidase (DAO) enzyme dietary supplementation in subjects with insomnia symptoms and single nucleotide polymorphisms of the AOC1 gene: a randomized double-blind placebo-controlled study [PDF]
Sleep Medicine: XObjective: This exploratory study was designed to assess the effect of a diamine oxidase (DAO) enzyme supplement on insomnia symptoms in patients with alterations of the AOC1 gene, which encodes the DAO enzyme.
Júlia Ferrer-Garcia +6 more
doaj +2 more sources
Estimation of serum levels of mast cells-related chymase, histamine and diamine oxidase in oral submucous fibrosis- a preliminary report [PDF]
BMC Oral Healthbackground Mast cell infiltration in oral submucous fibrosis (OSMF) has been drawn in to play a definitive role in initiation, progression, and symptom like burning sensation.
Harshkant Gharote +2 more
doaj +2 more sources