Diamine oxidase (DAO) supplement reduces headache in episodic migraine patients with DAO deficiency: A randomized double-blind trial [PDF]
Clinical Nutrition, 2019 Histamine intolerance is a disorder in the homeostasis of histamine due to a reduced intestinal degradation of this amine, mainly caused by a deficiency in the enzyme diamine oxidase (DAO). Among histamine related symptoms, headache is one of the most recorded. Current clinical strategies for the treatment of the symptomatology related to this disorder
M Carmen Vidal-Carou +2 more
exaly +6 more sources
Measurement of diamine oxidase (DAO) during low-histamine or ordinary diet in patients with histamine intolerance. [PDF]
Eur J Clin NutrAbstract Background/Objectives Quantification of diamine oxidase (DAO) concentrations in serum has been proposed as an adjunctive diagnostic modality for the evaluation of histamine intolerance (HIT).
Rentzos G +3 more
europepmc +5 more sources
Comparative characterization of diamine oxidase (DAO) activity from plant, animal and microbial matrices [PDF]
Food BioscienceHistamine intolerance is associated with impaired histamine metabolism caused by a deficiency of the enzyme diamine oxidase (DAO). A recommended strategy to alleviate symptoms is a low-histamine diet supplemented with exogenous DAO. Recent studies suggest plant-based DAO from legume sprouts could be a viable active ingredient for supplements.
Lutz Fischer +2 more
exaly +5 more sources
Testosterone as Diamine Oxidase Activity Regulator [PDF]
BioDiscovery, 2017 Diamine oxidase (DAO) is a key enzyme of the metabolism of polyamines. Its activity was assayed in homogenate of male immature rat liver and kidney. The androgens are important regulators of polyamines’ metabolism.
Milena Mishonova, Hristo Gagov
doaj +5 more sources
Plasma diamine oxidase activity in asthmatic children [PDF]
Allergology International, 1996 Histamine plays an important role in the development of asthmatic symptoms. Diamine oxidase (DAO histaminase), which inactivates histamine, is located in the intestine and kidney and is released into plasma.
Kyoichiro Toyoshima +8 more
doaj +2 more sources
Advances in the Clinical Application of Histamine and Diamine Oxidase (DAO) Activity: A Review [PDF]
Catalysts, 2022 The serum level of diamine oxidase (DAO) reflects the integrity and maturation of the small intestinal mucosa. This measure is important in diagnosing various diseases, including chronic urticaria tachyphylaxis, multiple organ dysfunction syndrome, preterm abortion, and migraine.
Zhaowang Tan +7 more
openaire +2 more sources
Effect of diamine oxidase (DAO) enzyme dietary supplementation in subjects with insomnia symptoms and single nucleotide polymorphisms of the AOC1 gene: a randomized double-blind placebo-controlled study [PDF]
Sleep Medicine: XObjective: This exploratory study was designed to assess the effect of a diamine oxidase (DAO) enzyme supplement on insomnia symptoms in patients with alterations of the AOC1 gene, which encodes the DAO enzyme.
Júlia Ferrer-Garcia +6 more
doaj +2 more sources
Spatial and temporal dynamics of peroxidase and amine oxidase activity is linked to polyamines and lignin in wheat grains [PDF]
Biologia Plantarum, 2010 The regulation of contents and activities of peroxidase (POX), diamine oxidase (DAO) and polyamine oxidase (PAO) were determined in relation to polyamines and lignin content in wheat (Triticum aestivum L.) grains.
B. Asthir, S. Kaur, W. Spoor, T. Roitsch
doaj +2 more sources
Thermospermine Synthase (ACL5) and Diamine Oxidase (DAO) Expression Is Needed for Zygotic Embryogenesis and Vascular Development in Scots Pine. [PDF]
Front Plant Sci, 2019 Unlike in flowering plants, the detailed roles of the enzymes in the polyamine (PA) pathway in conifers are poorly known. We explored the sequence conservation of the PA biosynthetic genes and diamine oxidase (DAO) in conifers and flowering plants to reveal the potential functional diversification of the enzymes between the plant lineages.
Vuosku J +8 more
europepmc +7 more sources
Evaluation of the Safety and Tolerability of Three Single Ascending Doses of Diamine Oxidase (DAO) in Healthy Volunteers: A Randomized Clinical Trial [PDF]
International Journal of Translational MedicineBackground/Objectives: Diamine oxidase (DAO) enzyme metabolizes dietary histamine in the gastrointestinal tract. DAO deficiency can lead to histamine intolerance (HIT), manifesting as migraines, gastrointestinal disturbances, and allergic reactions.
Pol Molina Perelló +8 more
doaj +2 more sources