Effect of diamine oxidase (DAO) enzyme dietary supplementation in subjects with insomnia symptoms and single nucleotide polymorphisms of the AOC1 gene: a randomized double-blind placebo-controlled study [PDF]
Sleep Medicine: XObjective: This exploratory study was designed to assess the effect of a diamine oxidase (DAO) enzyme supplement on insomnia symptoms in patients with alterations of the AOC1 gene, which encodes the DAO enzyme.
Júlia Ferrer-Garcia +6 more
doaj +2 more sources
[Studies on diamine oxidase (DAO) activity in seminal plasma]. [PDF]
Hinyokika kiyo. Acta urologica Japonica, 1989 Diamine oxidase (DAO: EC 1.4.3.6) activity was measured for seminal plasma of patients complaining of infertility to investigate whether measurement of DAO activity in seminal plasma is a significant laboratory examination or not for evaluation of male infertility.
Y, Uchijima +3 more
openaire +2 more sources
Biologia Plantarum, 2010 The regulation of contents and activities of peroxidase (POX), diamine oxidase (DAO) and polyamine oxidase (PAO) were determined in relation to polyamines and lignin content in wheat (Triticum aestivum L.) grains.
B. Asthir, S. Kaur, W. Spoor, T. Roitsch
doaj +2 more sources
A case series of diamine oxidase deficiency misdiagnosed as anxiety or panic attacks in patients with tachycardia [PDF]
Indian Journal of PsychiatryBackground: Diamine oxidase (DAO) deficiency, a key marker of histamine intolerance (HIT), often mimics anxiety or panic disorders, leading to a misdiagnoses and delayed treatment.
Ilkay Keskinel
doaj +2 more sources
Plant-Derived Diamine Oxidase Modulation of Histamine-Induced Ca2+ Release in Intestinal Caco-2 Cells: A Cellular System to Evaluate Its Histaminase Efficacy [PDF]
CellsHistamine accumulation is associated with allergic reactions and intestinal dysfunction through activation of H1R Receptors (H1Rs) and subsequent intracellular Ca2+ mobilization.
Armelle Tchoumi Neree +4 more
doaj +2 more sources
International Journal of Translational MedicineBackground/Objectives: Diamine oxidase (DAO) enzyme metabolizes dietary histamine in the gastrointestinal tract. DAO deficiency can lead to histamine intolerance (HIT), manifesting as migraines, gastrointestinal disturbances, and allergic reactions.
Pol Molina Perelló +8 more
doaj +2 more sources
Mapping of the binding sites of human diamine oxidase (DAO) monoclonal antibodies. [PDF]
Inflamm Res, 2018 Recently we characterized five mouse monoclonal antibodies that allow the specific and sensitive detection of human diamine oxidase (DAO). To understand differences in binding characteristics and recognition of enzyme variants, we mapped the antibody binding sites.Fragments of human DAO were expressed as glutathione-S-transferase fusion proteins that ...
Schwelberger HG, Feurle J, Houen G.
europepmc +4 more sources
Optimization of agro-technological processing parameters to enhance diamine oxidase activity in edible legume sprouts [PDF]
Journal of Agriculture and Food ResearchHistamine intolerance is associated with impaired histamine metabolism caused by a deficiency of the enzyme diamine oxidase (DAO). A recommended strategy to alleviate symptoms is a low-histamine diet supplemented with exogenous DAO.
Judit Costa-Catala +5 more
doaj +2 more sources
Is histamine intolerance a treatable subtype of fibromyalgia? evidence and clinical implications—narrative review [PDF]
Frontiers in Pain ResearchBackgroundFibromyalgia affects 2%–8% of the global population with suboptimal treatment outcomes. Emerging evidence suggests histamine intolerance, mediated by diamine oxidase (DAO) deficiency, may contribute to fibromyalgia pathophysiology in specific ...
João Protásio Netto +6 more
doaj +2 more sources
Applied Food ResearchHistamine intolerance is associated with impaired histamine metabolism due to diamine-oxidase (DAO) enzyme deficiency at intestinal level. The recommended strategy to alleviate the symptomatology is a low-histamine diet supplemented with DAO.
Mariluz Latorre-Moratalla +2 more
exaly +3 more sources