Prevalence of Diamine Oxidase Enzyme (DAO) Deficiency in Subjects with Insomnia-Related Symptoms
Background/Objectives: To assess the prevalence of diamine oxidase (DAO) enzyme deficiency caused by single nucleotide polymorphisms (SNPs) of the AOC1 gene in a sample of patients with symptoms of insomnia. Methods: A total of 167 adult patients (> 18 years of age) with symptoms of insomnia attended in a specialized institute for healthy ...
Raquel López García +3 more
openaire +3 more sources
Toward food-grade production of the Glutamicibacter halophytocola diamine oxidase using Komagataella phaffii [PDF]
The diamine oxidase from Glutamicibacter halophytocola (DAO-GH) was recombinantly produced in K. phaffii using the constitutive glyceraldehyde-3-phosphate dehydrogenase promoter for methanol-free production. Firstly, K.
Anna Bechtel +4 more
doaj +2 more sources
Mapping of the binding sites of human diamine oxidase (DAO) monoclonal antibodies. [PDF]
Recently we characterized five mouse monoclonal antibodies that allow the specific and sensitive detection of human diamine oxidase (DAO). To understand differences in binding characteristics and recognition of enzyme variants, we mapped the antibody binding sites.Fragments of human DAO were expressed as glutathione-S-transferase fusion proteins that ...
Schwelberger HG, Feurle J, Houen G.
europepmc +4 more sources
Histamine intolerance is associated with impaired histamine metabolism due to diamine-oxidase (DAO) enzyme deficiency at intestinal level. The recommended strategy to alleviate the symptomatology is a low-histamine diet supplemented with DAO.
Judit Costa-Catala +2 more
exaly +3 more sources
Intestinal expression of diamine oxidase (DAO) and the relationship between blood DAO activity and haptoglobin concentration in diarrheal calves. [PDF]
The objectives of this study were (1) to confirm the expression of diamine oxidase (DAO) in the intestines of healthy calves immune-histologically and to clarify whether the expression of DAO in the intestines of calves with diarrhea differs from that of healthy animals, and (2) to clarify the relationship between DAO and intestinal inflammation using ...
Kozutsumi A +10 more
europepmc +3 more sources
Improvment of cold tolerance of chickpea through heavy polyamines catabolism and ethylene phytohormone [PDF]
Objective The current study was undertaken to investigate if there is a relationship between metabolism of ethylene and heavy polyamines (PAs) under cold stress in cold-tolerant and cold-sensitive chickpea (Cicer arietinum L.) genotypes.
Saeed Amini +2 more
doaj +1 more source
Introduction: The amine oxidase copper-containing 1 (AOC1) gene encodes for the diamine oxidase (DAO) enzyme. DAO is an enzyme that catabolizes some molecules, including histamine, and is the degradative enzyme in the polyamine catabolic pathway that is ...
Gülşah Okutan +11 more
doaj +1 more source
Degradation of histamine in tuna soup by diamine oxidase (DAO) [PDF]
Histamine is a biogenic amine, which can cause food poisoning when present at high concentrations (>500 ppm). In situations where the formation of histamine in food cannot be prevented through traditional methods such as refrigeration, diamine oxidase (DAO) enzyme may be a suitable method to reduce histamine concentration to safe levels.
A. Naila +5 more
openaire +1 more source
Role of diamine oxidase in the pathogenesis of chronic urticaria
Chronic urticaria is a polyetiological disease proceeding by various immunological and non-immunological (pseudo-allergic) mechanisms. Food intolerance is a distinct type of pseudo-allergies, manifesting, e.g., with histamine intolerance syndrome, caused
N. V. Mikryukova, N. M. Kalinina
doaj +1 more source
Semicarbazide diminishes the signs of bleomycin-induced pulmonary fibrosis in rats [PDF]
The pathogenesis of pulmonary fibrosis (PF) is accompanied by extracellular matrix (ECM) deposition, oxidative stress, and inflammation progression, as well as hyperactivation of amine oxidases (AOs), which contribute to disease manifestation.
O. O. Hudkova +5 more
doaj +1 more source

