Results 51 to 60 of about 4,548 (205)

Markedly Increased Diamine Oxidase During Acute Anaphylaxis Is Associated With an Underlying Clonal Mast Cell Disorder

open access: yesClinical &Experimental Allergy, EarlyView.
We provide the first evidence that pronounced release of DAO during anaphylaxis is restricted to patients with clonal mast cell disorder. This finding offers possible functional support for the reported association between KIT p.D816V and anaphylaxis severity.
Matija Rijavec   +5 more
wiley   +1 more source

Basal Serum Diamine Oxidase Levels as a Biomarker of Histamine Intolerance: A Retrospective Cohort Study [PDF]

open access: yes, 2022
Background: Histamine Intolerance (HIT) is a multifaceted pseudoallergic disorder possibly due to defective histamine metabolism. Diamine oxidase (DAO) contributes to histamine degradation and can be measured in the serum.
Asperti C.   +9 more
core   +1 more source

Microbial‐Immune Interplay in CNS Autoimmune Diseases: Lessons from Animal Models and Clinical Studies

open access: yesEuropean Journal of Immunology, Volume 56, Issue 2, February 2026.
Mechanism of action of the intestinal microbiota on CNS autoimmune diseases. Environmental factors shape gut microbiota composition; dysbiosis alters microbial metabolites and antigenic signals. These modulate innate and adaptive immunity, affect barrier integrity, and influence CNS‐resident cells such as microglia and astrocytes, contributing to ...
Matteo Ceccon, Francesca Ronchi
wiley   +1 more source

The Rate of Histamine Degradation by Diamine Oxidase Is Compromised by Other Biogenic Amines

open access: yesFrontiers in Nutrition, 2022
Nowadays, certain uncertainties related to the onset of histamine adverse effects remain unsolved and still require further research. Questions still to be resolved include the wide range of doses at which dietary histamine may trigger symptoms of ...
Sònia Sánchez-Pérez   +20 more
doaj   +1 more source

How reliable and robust are current biomarkers for copper status? [PDF]

open access: yes, 2017
Cu is an essential nutrient for man, but can be toxic if intakes are too high. In sensitive populations, marginal over- or under-exposure can have detrimental effects.
Araya, Magdalena   +6 more
core  

Nitrate Enhances Gastric Mucosa Defense and Repair Process in Ethanol‐Induced Gastric Ulcer Rats via the Notch–Tff2 Pathway

open access: yesMedComm, Volume 7, Issue 2, February 2026.
Nitrate protects the three major barriers of the gastric mucosa, alleviating bleeding and inflammation of ethanol‐induced gastric ulcer in rats, and promotes migration of gastric epithelial cells, accelerating the restoration of the ulcerated epithelium, which is strongly related to TFF2, a gastric mucosal protective factor negatively regulated by the ...
Ying Liu   +10 more
wiley   +1 more source

N-acetyl glucosamine improves intestinal mucosal barrier function in rat

open access: yesBangladesh Journal of Pharmacology, 2012
Our study investigated the effect of N-acetylglucosamine (GlcNAc) on the intestinal mucosal barrier function in rats. Rats were randomly assigned into normal control group, diarrhea-predominant irritable bowel syndrome (IBS-D) group and GlcNAc group. IBS-
Yanxia Liu   +5 more
doaj   +1 more source

Prevalence of genetic diamine oxidase (DAO) deficiency in women with fibromyalgia in Spain

open access: yes, 2022
Abstract Diamine oxidase (DAO) is the enzyme responsible for the metabolism of intestinal histamine. Single nucleotide polymorphisms (SNPs) of the AOC1 gene are associated with low enzymatic activity or functionality in the metabolism of histamine.
Gülşah Okutan   +6 more
openaire   +1 more source

Medicago Sativa L. Saponin‐Driven Lactobacillus Intestinalis Restores Intestinal Stemness in Naturally Aged Mice via the Bile Acid‐FXR‐Wnt Signaling Axis

open access: yesAdvanced Science, Volume 13, Issue 4, 19 January 2026.
This study examines the mechanism by which alfalfa saponin (AS) regulates intestinal stemness via modulation of the gut microbiota. The results indicate that AS significantly increases the abundance of Lactobacillus intestinalis, which subsequently activates Wnt signaling via bile acid metabolism and enhances intestinal stemness. These findings provide
Mengqi Liu   +8 more
wiley   +1 more source

Colorimetric Biosensor Based on Magnetic Enzyme and Gold Nanorods for Visual Detection of Fish Freshness

open access: yesBiosensors, 2022
Histamine, an important safety index for aquatic products, can also be used as a freshness indicator for red-fleshed fish. In this work, magnetic graphene oxide (Fe3O4@GO, MGO) was applied to immobilize diamine oxidase (DAO) through a method of ...
Xia Xu   +5 more
doaj   +1 more source

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