Results 61 to 70 of about 4,748 (224)

Colonic Barrier Dysfunction and Inflammation Induced by Nano‐/Micro‐Plastics Fibers in Mice via the FAK/NF‐κB/iNOS and TLR4/NF‐κB/iNOS Pathways

Journal of Applied Toxicology, EarlyView.
ABSTRACT As emerging environmental contaminants, nano‐ and micro‐plastics (NMPs) have drawn increasing research attention due to potential hazards to organisms. Particle shape is a key factor influencing the toxic effects of NMPs, and NMPs of different shapes cause varying degrees of tissue damage. We investigated the specific mechanisms of polystyrene
Yuting Li, Shibo Bao, Puyang Huang, Jiahui Wang, Hongfeng Li, Yahong Liu, Kai Wang, Jianjun Du, Lingjun Yan, Guowei Pan, Wei Sun   +10 more
wiley   +1 more source

Human diamine oxidase is readily released from activated neutrophils ex vivo and in vivo but is rarely elevated in bacteremic patients

International Journal of Immunopathology and Pharmacology, 2020
During human diamine oxidase (DAO) ELISA development we noticed that in serum DAO concentrations appear to be higher when compared to plasma. Neutrophils contain DAO in the specific granules and we hypothesized that DAO is released from neutrophils ...
Thomas Boehm, Matthias Karer, Peter Matzneller, Nina Buchtele, Franz Ratzinger, Karin Petroczi, Christian Schoergenhofer, Michael Schwameis, Heinz Burgmann, Markus Zeitlinger, Bernd Jilma   +10 more
doaj   +1 more source

Variability in intracellular localization of D‐amino acid oxidase in choroid plexus epithelial cells

The FEBS Journal, EarlyView.
D‐amino acid oxidase (DAO) in choroid plexus epithelial cells (CPECs) shows vesicle‐like localization by histological and super‐resolution analyses. DAO colocalizes with peroxisomal, Golgi, endosomal, lysosomal, autophagosomal, and exosomal markers, indicating diverse subcellular distribution. This suggests DAO is transported within CPECs to metabolize
Koji Ono, Yuji Shishido, Toshiyuki Yamagishi, Kiyoshi Fukui   +3 more
wiley   +1 more source

N-acetyl glucosamine improves intestinal mucosal barrier function in rat

Bangladesh Journal of Pharmacology, 2012
Our study investigated the effect of N-acetylglucosamine (GlcNAc) on the intestinal mucosal barrier function in rats. Rats were randomly assigned into normal control group, diarrhea-predominant irritable bowel syndrome (IBS-D) group and GlcNAc group. IBS-
Yanxia Liu, Weiwei Xu, Lei Liu, Linming Guo, Yu Deng, Junkang Liu   +5 more
doaj   +1 more source

How reliable and robust are current biomarkers for copper status? [PDF]

, 2017
Cu is an essential nutrient for man, but can be toxic if intakes are too high. In sensitive populations, marginal over- or under-exposure can have detrimental effects.
Araya, Magdalena, Danzeisen, Ruth, Harrison, Brenda, Keen, Carl, McArdle, Harry J., Solioz, Marc, Thiele, Dennis   +6 more
core  

Magnolol Improves Intestinal Antioxidant Capacity and Barrier Function by Activating the Nrf2 Signaling Pathway in a Piglet Model

Food Frontiers, Volume 7, Issue 3, May 2026.
ABSTRACT Magnolol is a natural bioactive phenolic compound with potent antioxidant properties and plays an important role in modulating intestinal healthy. However, the underlying mechanisms of magnolol in alleviating intestinal oxidative stress damage and improving the intestinal barrier integrity remain unknown. Thus, this study aimed to evaluate the
Mengyao Fang, Kang Yang, Yiyan Cui, Ting Rong, Dun Deng, Pan Yang, Zhimei Tian, Min Song, Xianyong Ma, Miao Yu   +9 more
wiley   +1 more source

The Rate of Histamine Degradation by Diamine Oxidase Is Compromised by Other Biogenic Amines

Frontiers in Nutrition, 2022
Nowadays, certain uncertainties related to the onset of histamine adverse effects remain unsolved and still require further research. Questions still to be resolved include the wide range of doses at which dietary histamine may trigger symptoms of ...
Sònia Sánchez-Pérez, Sònia Sánchez-Pérez, Sònia Sánchez-Pérez, Oriol Comas-Basté, Oriol Comas-Basté, Oriol Comas-Basté, Judit Costa-Catala, Judit Costa-Catala, Judit Costa-Catala, Irache Iduriaga-Platero, Irache Iduriaga-Platero, Irache Iduriaga-Platero, M. Teresa Veciana-Nogués, M. Teresa Veciana-Nogués, M. Teresa Veciana-Nogués, M. Carmen Vidal-Carou, M. Carmen Vidal-Carou, M. Carmen Vidal-Carou, M. Luz Latorre-Moratalla, M. Luz Latorre-Moratalla, M. Luz Latorre-Moratalla   +20 more
doaj   +1 more source

Lipoxin A4 preconditioning attenuates intestinal ischemia reperfusion injury through Keap1/Nrf2 pathway in a lipoxin A4 receptor independent manner [PDF]

, 2016
published_or_final_versio
Han, X, Hei, Z, Li, H, LIU, Z, Xia, Z, Yao, W, Zhang, Z   +6 more
core   +3 more sources

Monitoring Biogenic Amines: Comparative Assessment of Detection Methods for Key Market Marine and Freshwater Species

Journal of Food Science, Volume 91, Issue 5, May 2026.
ABSTRACT Biogenic amines, primarily histamine, cadaverine, and putrescine, are important indicators of microbial spoilage and potential health risks. This review summarizes established and novel analytical methods for quantitatively determining biogenic amines in fish and fish products, along with their limits of detection in these complex matrices ...
Lasse Petersen
wiley   +1 more source

Markedly Increased Diamine Oxidase During Acute Anaphylaxis Is Associated With an Underlying Clonal Mast Cell Disorder

Clinical &Experimental Allergy, Volume 56, Issue 5, Page 516-525, May 2026.
We provide the first evidence that pronounced release of DAO during anaphylaxis is restricted to patients with clonal mast cell disorder. This finding offers possible functional support for the reported association between KIT p.D816V and anaphylaxis severity.
Matija Rijavec, Žan Kogovšek, Jezerka Inkret, Peter Kopač, Mitja Košnik, Peter Korošec   +5 more
wiley   +1 more source