Cytopathic bovine viral diarrhea viruses (BVDV): emerging pestiviruses doomed to extinction [PDF]
Veterinary Research, 2010 Bovine viral diarrhea virus (BVDV), a Flaviviridae pestivirus, is arguably one of the most widespread cattle pathogens worldwide. Each of its two genotypes has two biotypes, non-cytopathic (ncp) and cytopathic (cp).
E. Peterhans +3 more
semanticscholar +5 more sources
Metagenomic Investigation of Pathogenic RNA Viruses Causing Diarrhea in Sika Deer Fawns. [PDF]
VirusesDiarrhea is a common disease in sika deer. The causes of diarrhea in sika deer are complex and involve a variety of pathogens. Additionally, new virulent pathogens are continuously emerging, which poses a serious threat to deer’s health and particularly ...
Wang W +7 more
europepmc +2 more sources
Recovery of cytopathogenic and noncytopathogenic bovine viral diarrhea viruses from cDNA constructs [PDF]
Journal of Virology, 1996 After cDNA cloning of the genome of bovine viral diarrhea virus (BVDV) isolate CP7, a full-length cDNA clone was constructed. RNA transcribed in vitro from this construct was shown to direct the generation of infectious BVDV upon transfection into bovine cells.
G. Meyers +4 more
semanticscholar +4 more sources
A CRISPR/Cas9 Generated Bovine CD46-knockout Cell Line—A Tool to Elucidate the Adaptability of Bovine Viral Diarrhea Viruses (BVDV) [PDF]
Viruses, 2020 Bovine viral diarrhea virus (BVDV) entry into a host cell is mediated by the interaction of the viral glycoprotein E2 with the cellular transmembrane CD46 receptor.
K. P. Szillat +4 more
semanticscholar +4 more sources
Antigenic variations in bovine viral diarrhea viruses detected by monoclonal antibodies
Journal of Clinical Microbiology, 1990 Five murine monoclonal antibodies (MAbs) against the NADL strain of bovine viral diarrhea (BVD) virus were developed, identified, and characterized. Four of the MAbs were directed against a 53-kilodalton (kDa) viral protein, and one was specific to a 47-kDa polypeptide. Competitive radioimmunoassay showed that two MAbs were specific to related epitopes
W. Xue, F. Blecha, H. Minocha
semanticscholar +4 more sources
Molecular characterization of ten viral pathogens causing calf diarrhea in Hanwoo (Bos Taurus coreanae) by next generation sequencing. [PDF]
BMC Vet ResBackground Calf diarrhea remains a significant concern in the global cattle industry, leading to considerable economic losses. Infectious pathogens are among the primary causes of this disease.
Chae JB, Kim WG, Song S, Chae JS.
europepmc +2 more sources
Detection and Characterization of Genetic Recombination in Cytopathic Type 2 Bovine Viral Diarrhea Viruses [PDF]
Journal of Virology, 2000 ABSTRACT In cytopathic bovine viral diarrhea virus genotype 1 (BVDV1) isolates, insertions are reported at position A (amino acid [aa] 1535) and position B (aa 1589). Insertions at position B predominate. In this survey it was found that in BVDV2, insertions at position A predominate. Possible reasons for this difference in relative frequency
J. Ridpath, J. Neill
semanticscholar +4 more sources
Journal of Veterinary Medical Science, 2015 In our previous study, we genetically analyzed bovine viral diarrhea viruses (BVDVs) isolated from 2000 to 2006 in Japan and reported that subgenotype 1b viruses were predominant.
Yuri Abe +14 more
semanticscholar +6 more sources
Differences in virulence between two noncytopathic bovine viral diarrhea viruses in calves.
American Journal of Veterinary Research, 1992 A noncytopathic bovine viral diarrhea virus (BVDV), BVDV-890, isolated from a yearling heifer that died with extensive internal hemorrhages, was compared for virulence in calves with noncytopathic BVDV-TGAN, isolated from an apparently healthy ...
S R Bolin, J. Ridpath
semanticscholar +3 more sources
Typing of Bovine Viral Diarrhea Viruses Directly from Blood of Persistently Infected Cattle by Multiplex PCR [PDF]
Journal of Clinical Microbiology, 1999 ABSTRACT A nested multiplex PCR was developed for genotyping of bovine viral diarrhea viruses (BVDVs). The assay could detect as little as 3 50% tissue culture infective doses of BVDV per ml and typed 42 out of 42 cell culture isolates. BVDV was also successfully typed, with or without RNA extraction, from all 27 whole-blood samples examined ...
S. Gilbert +3 more
semanticscholar +4 more sources