Results 131 to 140 of about 1,117 (151)
Some of the next articles are maybe not open access.
Bioorganic & Medicinal Chemistry, 2010
A new group of 2,3-diarylquinoline derivatives possessing a methylsulfonyl COX-2 pharmacophore at the para-position of the C-2 phenyl ring were synthesized and evaluated as selective COX-2 inhibitors. In vitro COX-1/COX-2 structure-activity relationships were determined by varying the substituents on the C-4 quinoline ring.
Razieh, Ghodsi +3 more
openaire +2 more sources
A new group of 2,3-diarylquinoline derivatives possessing a methylsulfonyl COX-2 pharmacophore at the para-position of the C-2 phenyl ring were synthesized and evaluated as selective COX-2 inhibitors. In vitro COX-1/COX-2 structure-activity relationships were determined by varying the substituents on the C-4 quinoline ring.
Razieh, Ghodsi +3 more
openaire +2 more sources
ChemInform, 2008
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Xiang‐Shan Wang +4 more
openaire +1 more source
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Xiang‐Shan Wang +4 more
openaire +1 more source
Selection and prioritization of candidate combination regimens for the treatment of tuberculosis.
Science Translational MedicineAccelerated tuberculosis drug discovery has increased the number of plausible multidrug regimens. Testing every drug combination in vivo is impractical, and varied experimental conditions make it challenging to compare results between experiments.
Natasha Strydom +7 more
semanticscholar +1 more source
Candidate anti-tuberculosis medicines and regimens under clinical evaluation.
Clinical Microbiology and InfectionBACKGROUND Tuberculosis (TB) is the leading cause of mortality by an infectious disease world-wide. Despite national and international efforts, the world is not on track to end TB by 2030.
Michael Hoelscher +7 more
semanticscholar +1 more source
Organic Letters
An efficient and sustainable approach for the synthesis of 2,4-diarylquinolines has been developed via a visible-light-promoted metal-free three-component decarboxylative annulation pathway. This one-pot protocol combines readily available feed-stock α,β-
Suman Das +5 more
semanticscholar +1 more source
An efficient and sustainable approach for the synthesis of 2,4-diarylquinolines has been developed via a visible-light-promoted metal-free three-component decarboxylative annulation pathway. This one-pot protocol combines readily available feed-stock α,β-
Suman Das +5 more
semanticscholar +1 more source
Revolutionizing TB treatment: Breakthrough antibiotics for a healthier future A comprehensive review
International Journal of Science and Research ArchiveThe current treatment regiment for DS-TB(Drug Resistant Tuberculosis) was defined by 1980's since then the emergency of HIV and escalation of Drug sensitive (DS-TB)forms of TB have presented new challenges.To face these challenges, achieve goals like ...
Kamatam Meghana +3 more
semanticscholar +1 more source
Once-Weekly Treatment of Tuberculosis with the Diarylquinoline R207910: A Real Possibility
American Journal of Respiratory and Critical Care Medicine, 2009Eric, Nuermberger, Denis A, Mitchison
openaire +2 more sources
The Diarylquinoline TMC207 for Multidrug-Resistant Tuberculosis
Yearbook of Pediatrics, 2011openaire +1 more source
Environmentally benign synthesis of 2,4-diarylquinolines under metal- & solvent-free conditions
Tetrahedron Letters, 2023Sabina Yashmin, Abu Taleb Khan
exaly