Results 171 to 180 of about 6,473 (220)
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2012
This chapter addresses diastereoselectivity. It explains how to make compounds as single diastereoisomers. The chapter begins by differentiating between stereospecific and stereoselective reactions. In stereospecific reactions, the mechanism means that the stereochemistry of the starting material determines the stereochemistry of the product and there ...
Jonathan Clayden +2 more
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This chapter addresses diastereoselectivity. It explains how to make compounds as single diastereoisomers. The chapter begins by differentiating between stereospecific and stereoselective reactions. In stereospecific reactions, the mechanism means that the stereochemistry of the starting material determines the stereochemistry of the product and there ...
Jonathan Clayden +2 more
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Photoinduced Diastereoselective Aminoalkylation of Cubanes
Organic Letters, 2023The unique properties of rigid, nonconjugated hydrocarbons provide many opportunities to design molecular building blocks for a variety of applications, but the development of suitable conditions for alkylation of cubanes is quite challenging. Herein, a photoinduced method for aminoalkylation of cubanes is reported. The benign conditions reported allow
Guillaume Levitre +2 more
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Diastereoselective epoxidation of dipeptide olefins
Tetrahedron Letters, 1993Abstract m-Chloroperbenzoic acid (MCPBA) epoxidation of dipeptide olefins proceeds in high syndiastereoselectivity (38:1–300:1). This is partially caused by conformational constants introduce by the side chain that orients the allylic NH in a favorable position for hydrogen bonding to MCPBA.
S. ROMEO, D. RICH
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Diastereoselective Total Synthesis of Raputindole A
Organic Letters, 2018The first diastereoselective total synthesis of the bisindole alkaloid raputindole A is reported. After Au(I)-catalyzed assembly of the cyclopenta[ f]indole tricycle, it was possible to hydrogenate the indene double bond regio- and diastereoselectively through iridium catalysis, guided by a preinstalled hydroxy function.
Mario Kock, Thomas Lindel
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Cyclohexylcarbonitriles: Diastereoselective Arylations with TMPZnCl·LiCl
The Journal of Organic Chemistry, 2012Deprotonating substituted cyclohexanecarbonitriles with TMPZnCl·LiCl affords zincated nitriles that diastereoselectively couple with aryl bromides in the presence of catalytic Pd(OAc)(2) and S-Phos. Steric and electronic effects influence the diastereoselectivity; 4-t-butyl-, 4-TBSO-, and 2-Me-cyclohexanecarbonitriles exert virtually complete ...
Robert J, Mycka +5 more
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Diastereoselective Preparation of Azetidines and Pyrrolidines
Organic Letters, 2010Iodine-mediated cyclization of homoallyl amines at room temperature delivered cis-2,4-azetidine through a 4-exo trig cyclization. Isomerization of iodo-azetidines to cis-pyrrolidines could be achieved by heating, with complete stereocontrol. The relative stereochemistry of the iodo-azetidines and pyrrolidines was confirmed by NMR spectroscopy and X-ray
Antonio, Feula +2 more
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Diastereoselective Alkylations of a Protected Cysteinesulfenate
The Journal of Organic Chemistry, 2009To further understand stereoselection in the alkylation of sulfenate anions, a protected cysteinesulfenate was generated in THF solution at low temperature. Introduction of a reactive alkylating agent brings about a cysteinyl sulfoxide in 51-75% yield, with diastereomeric ratios at the sulfinyl group ranging from 83:17 to 95:5.
Adrian L, Schwan +4 more
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Enantio- and diastereoselective Darzens condensations
Tetrahedron Letters, 2007AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Achard TJR +5 more
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Diastereoselective Hydroboration of Isopropenylcyclopropanes
The Journal of Organic Chemistry, 1999Janine, Cossy +3 more
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Diastereoselective Cyclopentane Construction
The Journal of Organic Chemistry, 2000, Taber, , Wang, , Pahutski
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