Results 1 to 10 of about 8,376 (166)
Photocatalytic Stereoselective Editing of Alkynes to 3D Molecules via Hydrogen Atom Transfer-Mediated Dynamic Epimerization [PDF]
Nature CommunicationsThree-dimensional molecules have drawn tremendous attention due to their pivotal roles in drug discovery as saturated bioisosteres of benzenoids. The direct construction of these scaffolds from simple and readily available one-dimensional building blocks
Zhenyu Gu +4 more
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Diastereodivergent electrophilic trapping of α-boryl lithium derivatives [PDF]
Beilstein Journal of Organic Chemistryα-Boryl carbanions are valuable organoboron intermediates, but controlling their stereoselective reactions remains challenging. Here, we examine the diastereoselective generation and trapping of α-boryl lithium species formed by ring opening of ...
Tereza Pavlíčková +2 more
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Results in Chemistry, 2022 Iodine-promoted dimerization of enolates of methyl 2-arylacetates generated with tBuOK under equilibrium conditions are reported. The oxidative homocoupling reaction furnishes a mixture of dl and meso dimers in moderate to good yields and ...
Ahmed Y. Nuriye, Joseph Barr
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Frontiers in Chemistry, 2021 Chemical synthesis based on Group-Assisted Purification chemistry (GAP) has been prolifically used as a powerful, greener and ecofriendly tool so far. Herein, we report hypervalent iodine (III) mediated regio- and diastereoselective aminobromination of ...
Anis Ur Rahman +6 more
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Molecules, 2022 Isospongian diterpenes are a small but growing family of natural tetracyclic secondary metabolites isolated from marine organisms, primarily sponges and nudibranchs.
Yurii V. Kharitonov, Elvira E. Shults
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Temperature-Controlled Diastereoselective Doebner/Ugi Tandem Reaction
SynOpen, 2023 Novel peptidomimetics containing a pyrrolone fragment were synthesized by a tandem combination of Doebner and Ugi type multicomponent reactions with controlled diastereoselectivity. This approach represents a convenient synthesis in the temperature range
Yana Sakhno +9 more
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Synthesis of the [11]Cyclacene Framework by Repetitive Diels–Alder Cycloadditions
Molecules, 2021 The Diels–Alder cycloaddition between bisdienes and bisdienophile incorporating the 7-oxa-bicyclo[2.2.1]heptane unit are well known to show high diastereoselectivity that can be exploited for the synthesis of molecular belts. The related bisdiene 5,6,7,8-
John B. Bauer +4 more
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Highly Diastereoselective Synthesis of Spiropyrazolones [PDF]
Molecules, 2015 We report a highly diastereoselective synthesis of spiropyrazolones catalyzed by secondary amines. The reported Michael-Aldol cascade reaction affords the desired spiropyrazolones bearing four chiral centers as a single diastereomer in excellent yields.
Ceban, Victor +3 more
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Diastereoselective Synthesis of Benzoxanthenones
Chemistry – An Asian Journal, 2020 Abstract An oxidative catalytic vanadium(V) system was developed to access the naturally nonabundant diastereomers of carpanone from the corresponding alkenyl phenol monomer in one pot by tandem oxidation, oxidative coupling, and 4+2 cyclization. This system was applied to the synthesis of two other analogues of carpanone.
Erika Neuhaus, Marisa C Kozlowski
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Cyclic Nitriles: Diastereoselective Alkylations [PDF]
The Journal of Organic Chemistry, 2005 AbstractFor Abstract see ChemInform Abstract in Full Text.
Fraser F, Fleming +4 more
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