Results 61 to 70 of about 6,130 (153)
NERP‐4–Deleted VGF Impairs β‐Cell Granulogenesis and Insulin Secretion
The FASEB Journal, Volume 39, Issue 24, 31 December 2025.Neuroendocrine regulatory peptide‐4 (NERP‐4) processed from the VGF promotes insulin secretion and β‐cell maintenance by acting on the amino acid transporter SNAT2. VGF△NERP‐4 impaired β‐cell granulogenesis and granule replenishment needed for the second‐phase insulin secretion.
Weidong Zhang +8 more
wiley +1 more source
Case Report: Diazoxide-induced diabetic ketoacidosis in a patient with insulinoma
Frontiers in EndocrinologyDefinitive management of insulinoma is challenging as curative surgery is associated with a considerable risk of morbidity and mortality. The successful long-term use of diazoxide for patients diagnosed with insulinoma has been described, but rarely, the
Run Ting Chin +3 more
doaj +1 more source
Insulinoma in a dog (Canis lupus familiaris) with concurrent non‐cardiogenic pulmonary oedema
Veterinary Record Case Reports, Volume 13, Issue 4, December 2025.Abstract A 12‐year‐old, female, neutered beagle presented with hypoglycaemia, sudden‐onset non‐ambulatory tetraparesis and a single tonic‐clonic seizure. Computed tomography revealed a pancreatic nodule, consistent with an insulinoma, an enlarged hepatic lymph node and ground‐glass attenuation of the lung parenchyma, most consistent with non ...
Dylan O’ Toole +5 more
wiley +1 more source
Sirolimus therapy in a child with partially diazoxide-responsive hyperinsulinaemic hypoglycaemia
Endocrinology, Diabetes & Metabolism Case Reports, 2016 Hyperinsulinaemic hypoglycaemia (HH), which causes persistent neonatal hypoglycaemia, can result in neurological damage and it’s management is challenging.
Kah-Yin Loke +5 more
doaj +1 more source
Erythematous Papules and Plaques in an Infant Receiving Glucagon Therapy
JEADV Clinical Practice, Volume 4, Issue 5, Page 1263-1266, December 2025.
Sara Al Janahi +4 more
wiley +1 more source
Anticonvulsant Effect of Diazoxide against Dichlorvos-Induced Seizures in Mice
The Scientific World Journal, 2013 Dichlorvos, a synthetic organophosphate toxin, is used as pesticides. These toxins can be used as pesticides in farming and medicine for the devastation and/or elimination of ectoparasites of animals.
Amin Jazayeri +2 more
doaj +1 more source
Severe transient neonatal hyperinsulinism: First Peruvian case series
SAGE Open Medical Case ReportsCongenital hyperinsulinism is characterized by dysregulated insulin secretion and is the most common and severe cause of persistent hypoglycemia in pediatrics. Brain damage rates can be as high as 50% due to inadequate treatment.
Manuel André Virú-Loza +2 more
doaj +1 more source
مجله دانشگاه علوم پزشکی گرگان, 2010 Background and Objective: Until now there is no drug formulated to prevent Neuronal Loss following Brain Stroke. In this study, we compared the effects of the mitoKATP opener, diazoxide, on ultra-structural morphology changes following in cortical ...
Katebi M (PhD) +5 more
doaj
JCRPEHomozygous or compound heterozygous mutations in insulin receptor gene (INSR) lead to marked insulin resistance and hyperglycaemia in Donohue syndrome and Rabson-Mendenhall syndrome, conditions which are associated with significant morbidity early in ...
Sarah Wing-Yiu Poon +3 more
doaj +1 more source