Results 1 to 10 of about 52,842 (247)

Acute stress and multicellular development alter the solubility of the Dictyostelium Sup35 ortholog ERF3 [PDF]

open access: yesMicrobiology Spectrum
Among sequenced organisms, the genome of Dictyostelium discoideum is unique in that it encodes for a massive amount of repeat-rich sequences in the coding region of genes.
Felicia N. Williams   +5 more
doaj   +2 more sources

Multi-color fluorescence live-cell imaging in Dictyostelium discoideum [PDF]

open access: yesCell Structure and Function
The cellular slime mold Dictyostelium discoideum, a member of the Amoebozoa, has been extensively studied in cell and developmental biology. D. discoideum is unique in that they are genetically tractable, with a wealth of data accumulated over half a ...
Hidenori Hashimura   +8 more
doaj   +2 more sources

Diverse Roles of the Multiple Phosphodiesterases in the Regulation of Cyclic Nucleotide Signaling in Dictyostelium [PDF]

open access: yesCells
Dictyostelium is a unique model used to study the complex and interactive cyclic nucleotide signaling pathways that regulate multicellular development.
Pundrik Jaiswal, Alan R. Kimmel
doaj   +2 more sources

Opposite functions of RapA and RapC in cell adhesion and migration in Dictyostelium

open access: yesAnimal Cells and Systems, 2021
There are three Rap proteins in Dictyostelium. RapA is a key regulator of cell adhesion and cytoskeletal rearrangement. Recently, RapC has been reported to be involved in cytokinesis, cell migration, and multicellular development.
Jihyeon Jeon   +2 more
doaj   +1 more source

Dictyostelium AMPKα regulates aggregate size and cell-type patterning [PDF]

open access: yesOpen Biology, 2017
Starved Dictyostelium cells aggregate into groups of nearly 105 cells. AMPK is a highly conserved serine/threonine protein kinase consisting of a catalytic and two regulatory subunits.
Ranjana Maurya   +2 more
doaj   +1 more source

The phenotypes of ATG9, ATG16 and ATG9/16 knock-out mutants imply autophagy-dependent and -independent functions [PDF]

open access: yesOpen Biology, 2015
Macroautophagy is a highly conserved intracellular bulk degradation system of all eukaryotic cells. It is governed by a large number of autophagy proteins (ATGs) and is crucial for many cellular processes.
Qiuhong Xiong   +4 more
doaj   +1 more source

Dictyostelium spastin is involved in nuclear envelope dynamics during semi-closed mitosis

open access: yesNucleus, 2022
Dictyostelium amoebae perform a semi-closed mitosis, in which the nuclear envelope is fenestrated at the insertion sites of the mitotic centrosomes and around the central spindle during karyokinesis.
Ulrike Schweigel   +4 more
doaj   +1 more source

The dictyostelium kinome--analysis of the protein kinases from a simple model organism. [PDF]

open access: yesPLoS Genetics, 2006
Dictyostelium discoideum is a widely studied model organism with both unicellular and multicellular forms in its developmental cycle. The Dictyostelium genome encodes 285 predicted protein kinases, similar to the count of the much more advanced ...
Jonathan M Goldberg   +6 more
doaj   +2 more sources

Gel purification of gDNA for next-generation sequencing applications

open access: yesBioTechniques, 2022
We demonstrate that gDNA can be conveniently and efficiently isolated and purified using standard agarose gel electrophoresis, band excision and gel purification.
Supanut Utthiya   +6 more
doaj   +1 more source

Dissecting the function of Atg1 complex in Dictyostelium autophagy reveals a connection with the pentose phosphate pathway enzyme transketolase [PDF]

open access: yesOpen Biology, 2015
The network of protein–protein interactions of the Dictyostelium discoideum autophagy pathway was investigated by yeast two-hybrid screening of the conserved autophagic proteins Atg1 and Atg8.
Ana Mesquita   +5 more
doaj   +1 more source

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