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Cell biology of Dictyostelium [PDF]

BMC Molecular and Cell Biology
The Cell Biology of Dictyostelium article collection highlights the benefits of using Dictyostelium as a model system for studying fundamental cellular processes.
Robert J. Huber, Paul A. Steimle, Cynthia K. Damer   +2 more
doaj   +2 more sources

Acute stress and multicellular development alter the solubility of the Dictyostelium Sup35 ortholog ERF3 [PDF]

Microbiology Spectrum
Among sequenced organisms, the genome of Dictyostelium discoideum is unique in that it encodes for a massive amount of repeat-rich sequences in the coding region of genes.
Felicia N. Williams, Kanesha L. Travis, Holly N. Haver, Anna D. Umano, Yaneli Guerra-Hernandez, K. Matthew Scaglione   +5 more
doaj   +2 more sources

Diverse Roles of the Multiple Phosphodiesterases in the Regulation of Cyclic Nucleotide Signaling in Dictyostelium [PDF]

Cells
Dictyostelium is a unique model used to study the complex and interactive cyclic nucleotide signaling pathways that regulate multicellular development.
Pundrik Jaiswal, Alan R. Kimmel
doaj   +2 more sources

Ammonia plus another factor are necessary for differentiation in submerged clumps of Dictyostelium [PDF]

, 1979
John Sternfeld, Charles N. David
openalex   +4 more sources

Opposite functions of RapA and RapC in cell adhesion and migration in Dictyostelium

Animal Cells and Systems, 2021
There are three Rap proteins in Dictyostelium. RapA is a key regulator of cell adhesion and cytoskeletal rearrangement. Recently, RapC has been reported to be involved in cytokinesis, cell migration, and multicellular development.
Jihyeon Jeon, Dongju Kim, Taeck Joong Jeon   +2 more
doaj   +1 more source

Dictyostelium AMPKα regulates aggregate size and cell-type patterning [PDF]

Open Biology, 2017
Starved Dictyostelium cells aggregate into groups of nearly 105 cells. AMPK is a highly conserved serine/threonine protein kinase consisting of a catalytic and two regulatory subunits.
Ranjana Maurya, Rakesh Kumar, Shweta Saran   +2 more
doaj   +1 more source

The phenotypes of ATG9, ATG16 and ATG9/16 knock-out mutants imply autophagy-dependent and -independent functions [PDF]

Open Biology, 2015
Macroautophagy is a highly conserved intracellular bulk degradation system of all eukaryotic cells. It is governed by a large number of autophagy proteins (ATGs) and is crucial for many cellular processes.
Qiuhong Xiong, Can Ünal, Jan Matthias, Michael Steinert, Ludwig Eichinger   +4 more
doaj   +1 more source

Dictyostelium spastin is involved in nuclear envelope dynamics during semi-closed mitosis

Nucleus, 2022
Dictyostelium amoebae perform a semi-closed mitosis, in which the nuclear envelope is fenestrated at the insertion sites of the mitotic centrosomes and around the central spindle during karyokinesis.
Ulrike Schweigel, Petros Batsios, Annette Müller-Taubenberger, Ralph Gräf, Marianne Grafe   +4 more
doaj   +1 more source

The dictyostelium kinome--analysis of the protein kinases from a simple model organism. [PDF]

PLoS Genetics, 2006
Dictyostelium discoideum is a widely studied model organism with both unicellular and multicellular forms in its developmental cycle. The Dictyostelium genome encodes 285 predicted protein kinases, similar to the count of the much more advanced ...
Jonathan M Goldberg, Gerard Manning, Allen Liu, Petra Fey, Karen E Pilcher, Yanji Xu, Janet L Smith   +6 more
doaj   +2 more sources

The Cell Density Factor CMF Regulates the Chemoattractant Receptor cAR1 in Dictyostelium [PDF]

, 1996
Starving Dictyostelium cells aggregate by chemotaxis to cAMP when a secreted protein called conditioned medium factor (CMF) reaches a threshold concentration.
Bishop, John D.,, Gomer, Richard H.,, Haastert, Peter J.M. van,   +2 more
core   +13 more sources