Results 81 to 90 of about 46,917 (300)

PTEN redundancy: overexpressing lpten, a homolog of Dictyostelium discoideum ptenA, the ortholog of human PTEN, rescues all behavioral defects of the mutant ptenA-. [PDF]

PLoS ONE, 2014
Mutations in the tumor suppressor gene PTEN are associated with a significant proportion of human cancers. Because the human genome also contains several homologs of PTEN, we considered the hypothesis that if a homolog, functionally redundant with PTEN ...
Daniel F Lusche, Deborah Wessels, Nicole A Richardson, Kanoe B Russell, Brett M Hanson, Benjamin A Soll, Benjamin H Lin, David R Soll   +7 more
doaj   +1 more source

Thermotaxis by pseudoplasmodia of Dictyostelium discoideum. [PDF]

Proceedings of the National Academy of Sciences, 1977
The temperature dependence of migration rate and of the thermotactic sensitivity of pseudoplasmodia of Dictyostelium discoideum has been measured. Migration rate increases with temperature to 20 degrees, is temperature insensitive from 20 degrees to 27.5 degrees, and decreases with temperature to 29 degrees, above which point migration ceases. However,
Kenneth L. Poff, Michiyo Skokut
openaire   +3 more sources

Fruiting bodies of the social amoeba Dictyostelium discoideum increase spore transport by Drosophila

BMC Evolutionary Biology, 2014
BackgroundMany microbial phenotypes are the product of cooperative interactions among cells, but their putative fitness benefits are often not well understood.
Jeff Smith, D. Queller, J. Strassmann
semanticscholar   +1 more source

Symbiotic bacteria, immune-like sentinel cells, and the response to pathogens in a social amoeba

Royal Society Open Science, 2023
Some endosymbionts living within a host must modulate their hosts' immune systems in order to infect and persist. We studied the effect of a bacterial endosymbiont on a facultatively multicellular social amoeba host.
Trey J. Scott, Tyler J. Larsen, Debra A. Brock, So Yeon Stacey Uhm, David C. Queller, Joan E. Strassmann   +5 more
doaj   +1 more source

Cooperative cell motility during tandem locomotion of amoeboid cells. [PDF]

, 2016
Streams of migratory cells are initiated by the formation of tandem pairs of cells connected head to tail to which other cells subsequently adhere. The mechanisms regulating the transition from single to streaming cell migration remain elusive, although ...
Bastounis, Effie, del Álamo, Juan C, Firtel, Richard A, Lasheras, Juan C, Álvarez-González, Begoña   +4 more
core   +2 more sources

Light Affects Host‐Symbiont Dynamics in the Non‐Photosynthetic Social Amoeba Symbiosis

Ecology and Evolution, Volume 15, Issue 4, April 2025.
This study highlights light‐regulated symbiosis between amoebae and two distinct Paraburkholderia species, indicating that light may be crucial for regulating amoebae‐symbiont dynamics. ABSTRACT Light significantly influences phototactic behaviors and host‐bacterial interactions of photosynthetic microorganisms such as algae.
Yuehui Tian, Lin Zhang, Zihe Wang, Zhili He, Longfei Shu   +4 more
wiley   +1 more source

Homeoprotein Hbx4 represses adhesion molecule governing cytokinesis and development [PDF]

, 2010
Homeobox genes encode proteins with a highly conserved DNA-binding motif and provoke morphological diversification of body segments by differentially controlling the expression of downstream targets.
Hyung-Soon Yim, Ji-Hui Seo, Ji-Sun Kim, Sa-Ouk Kang   +3 more
core   +1 more source

Micropillars in Cell Mechanobiology: Design, Fabrication, Characterization, and Biosensing Applications

Small Science, Volume 5, Issue 4, April 2025.
In this article, the pivotal role of micropillars in cell mechanobiology is explored, detailing their design, fabrication, and characterization. Novel applications in biosensing are highlighted, emphasizing their ability to modulate cellular environments and facilitate mechano‐stimulation.
Prabuddha De Saram, Nam‐Trung Nguyen, Sina Jamali, Navid Kashaninejad   +3 more
wiley   +1 more source

Detection and characterisation of NAD(P)H-diaphorase activity in Dictyostelium discoideum cells (Protozoa)

European Journal of Histochemistry, 2012
In Dictyostelium discoideum (D. discoideum), compounds generating nitric oxide (NO) inhibit its aggregation and differentiation without altering cyclic guanosine monophosphate (cGMP) production.
A. Amaroli, M.G. Chessa
doaj   +1 more source

Amino acid repeats cause extraordinary coding sequence variation in the social amoeba Dictyostelium discoideum. [PDF]

PLoS ONE, 2012
Protein sequences are normally the most conserved elements of genomes owing to purifying selection to maintain their functions. We document an extraordinary amount of within-species protein sequence variation in the model eukaryote Dictyostelium ...
Clea Scala, Xiangjun Tian, Natasha J Mehdiabadi, Margaret H Smith, Gerda Saxer, Katie Stephens, Prince Buzombo, Joan E Strassmann, David C Queller   +8 more
doaj   +1 more source