Results 41 to 50 of about 1,721 (143)

Comparative assessment of effectiveness of new drugs for targeted therapy of endometriosis by experimental model [PDF]

Гинекология, 2018
Introduction. The chronic, progressive, recurrent nature of the endometriosis results new avenues of targeted therapy for genital endometriosis with high therapeutic efficacy and minimal side effects must be explored.
M I Yarmoliskaya, M A Petrosyan, M S Florova, A S Molotkov, A S Denisova, E V Suslova, S Sh Tkhazaplizheva   +6 more
doaj   +1 more source

Dienogest and the breast

Gynecological Endocrinology, 2009
In a clinical pilot study, 21 women with endometriosis have been primarely treated with dienogest 2 x 10 mg daily p.o. for 24 weeks. Besides the effect on endometriosis the action of such high-dose progestogen treatment on the breast was evaluated by breast ultrasound prior to medication and at 24 weeks of medical treatment. In all women, a significant
Adolf E, Schindler, Alexandria, Henkel, Bernd, Christensen, Michel, Oettel, Claudia, Moore   +4 more
openaire   +2 more sources

Uterine “twisting sign”: A new potential ultrasonographic soft marker for deep endometriosis

International Journal of Gynecology &Obstetrics, Volume 171, Issue 3, Page 1355-1363, December 2025.
Abstract Objective The objective of the current study was to evaluate the “twisting sign,” defined as uterine fundus rotation observed on transvaginal sonography (TVS), as a potential soft marker for deep endometriosis (DE) and its association with specific DE localizations and indirect signs.
Fabio Barra, Simone Ferrero, Umberto Perrone, Giulio Evangelisti, Alessandra Pulliero, Alberto Izzotti, Umberto Leone Roberti Maggiore, Stefano Bogliolo   +7 more
wiley   +1 more source

Efficacy of oral contraceptive pills versus dienogest on endometriosis pain scores: a prospective cohort study

Middle East Fertility Society Journal
Background Endometriosis is a chronic gynecological condition associated with pelvic pain, dysmenorrhea, dyspareunia, and impaired quality of life. Medical management aims to reduce symptoms and prevent recurrence. The primary objective of this study was
Mahmoud Abdallah, Asmaa S. Mohamed, Ahmed Soliman, Walid M. Tawfik   +3 more
doaj   +1 more source

Role of suppression of endometriosis with progestins before IVF-ET: a non-inferiority randomized controlled trial

BMC Pregnancy and Childbirth, 2021
Background Endometriosis affects the responsiveness to ovarian stimulation. This study aimed to assess the role of Dienogest pretreatment for endometriosis suppression as compared to Gonadotropin-releasing hormone agonist (GnRHa) in patients with ...
Eissa Khalifa, Hashem Mohammad, Ameer Abdullah, Mazen Abdel-Rasheed, Mohammed Khairy, Mahmoud Hosni   +5 more
doaj   +1 more source

M2 Macrophages are Major Mediators of Germline Risk of Endometriosis and Explain Pleiotropy With Comorbid Traits

Advanced Science, Volume 12, Issue 41, November 6, 2025.
Genes associated with endometriosis risk are highly expressed in M2 macrophages, particularly ligands IL1A and IL1B. Endometrial‐type epithelium and stroma are likely recipients of these ligands. While IL1B treatment disturbs epithelial organization, blockage of the signaling results in a dose‐dependent decrease in spontanesous and evoked pain, reduces
Soledad Ochoa, Fernanda S. Rasquel‐Oliveira, Brett McKinnon, Marcela Haro, Sugarniya Subramaniam, Pak Yu, Simon Coetzee, Michael S. Anglesio, Kelly N. Wright, Raanan Meyer, Anne E. Porter, Caroline E. Gargett, Sally Mortlock, Grant W. Montgomery, Michael S. Rogers, Kate Lawrenson   +15 more
wiley   +1 more source

Body‐identical estrogens in combined hormonal contraceptives: A safer path forward

International Journal of Gynecology &Obstetrics, Volume 172, Issue 1, Page 654-656, January 2026.
Nathalie Chabbert‐Buffet, Ivonne J. Diaz Yamal, Jonathan Douxfils, Jean‐Michel Foidart, Franca Fruzzetti, Kristina Gemzell‐Danielsson, Rossella E. Nappi, Yutaka Osuga, Philippe Descamps   +8 more
wiley   +1 more source

Colo‐Ovarian Fistula With a Background of Endometriosis: A Report of Three Cases

Journal of Obstetrics and Gynaecology Research, Volume 51, Issue 11, November 2025.
ABSTRACT Patients with endometriosis are at a high risk of developing pelvic inflammatory disease. This case series presents three cases of colo‐ovarian fistulas associated with endometriosis, highlighting the potential for conservative management in selected cases.
Sayuri Fukaya, Gentaro Izumi, Kaori Koga, Yuko Sanada, Yasushi Hirota, Yutaka Osuga   +5 more
wiley   +1 more source

Long-term therapy with dienogest or other oral cyclic estrogen-progestogen can reduce the need for ovarian endometrioma surgery

Women's Health
Background: Almost 10% of women in reproductive age are diagnosed with ovarian endometriomas and can experience symptoms and infertility disorders. Ovarian endometriomas can be treated with medical or surgical therapy.
Federico Ferrari, Matteo Epis, Jvan Casarin, Giulia Bordi, Emanuele Baldo Gisone, Chiara Cattelan, Diego Oreste Rossetti, Giuseppe Ciravolo, Elisa Gozzini, Jacopo Conforti, Antonella Cromi, Antonio Simone Laganà, Fabio Ghezzi, Franco Odicino   +13 more
doaj   +1 more source

Efficacy of hormone pre‐treatment before ART to improve reproductive outcomes in infertile women with endometriosis: Network meta‐analysis of randomized controlled trials

International Journal of Gynecology &Obstetrics, Volume 170, Issue 3, Page 1001-1013, September 2025.
Abstract Background Hormone pre‐treatment is still used before assisted reproductive technique (ART) in endometriotic women, but evidence supporting this recommendation is conflicting. Objectives To evaluate whether hormone pre‐treatment with gonadotropin‐releasing hormone (GnRH) agonists or progestogens could improve fertility in women with ...
Gaetano Riemma, Luigi Cobellis, Antonio Simone Laganà, Andrea Etrusco, Luigi Della Corte, Marco Torella, Maria Giovanna Vastarella, Raffaela Maria Carotenuto, Pasquale De Franciscis   +8 more
wiley   +1 more source