Results 51 to 60 of about 2,521 (195)

A concept for a new approach to combined oral contraception from adolescence to perimenopause: Continuous use of the oral GnRH antagonist Relugolix and the fetal estrogen Estetrol

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 4, Page 568-574, April 2026.
It is expected that the relugolix estetrol combination RE4W will enable women to control their fertility and prevent menstrual cycle related problems, while offering a smooth transition through perimenopause into the postmenopause and decrease the risk of breast cancer.
Herjan J. T. Coelingh Bennink, Karolina Afors, Luis Bahamondes, Alessandra Graziottin, Deborah Bateson, Teresa Bombas, Yutaki Osuga, Santiago Palacios, Carolyn L. Westhoff, Kristina Gemzell‐Danielsson   +9 more
wiley   +1 more source

New ways in therapy of abnormal uterine bleedings related to adenomyosis [PDF]

Гинекология, 2015
The purpose of research was a comparison of the effect of a three-phase combined oral contraceptive (COC) containing estradiol valerate and dienogest in dynamic mode and single agent containing dienogest, to reduce menstrual blood loss on the background ...
N N Rukhliada, E I Biriukova, M A Melnikova, D M Gasimova   +3 more
doaj  

Associations between androgen levels and endurance training‐induced changes in body composition and physical performance in premenopausal females

Physiological Reports, Volume 14, Issue 7, April 2026.
Abstract We investigated whether a moderate‐intensity continuous training (MICT) for two menstrual/contraceptive cycles (~8 weeks) alters endogenous androgen concentrations in premenopausal females, and whether baseline androgen concentrations or their changes from baseline to post‐intervention are associated with adaptations in body composition and ...
Vera M. Salmi, Jari E. Karppinen, Maarit Lehti, Heikki Kyröläinen, Johanna K. Ihalainen, Ritva S. Mikkonen   +5 more
wiley   +1 more source

Long-term clinical outcomes of dienogest for perimenopausal women with symptomatic adenomyosis

Scientific Reports
We aimed to evaluate the successful long-term use of dienogest for the management of pelvic pain and bleeding control in perimenopausal women with symptomatic adenomyosis using real-world data. All women aged ≥ 40 years with adenomyosis who complained of
Chi-Hau Chen, Yi-Heng Lin, Chia-Yi Lee, Hung Shen, Ya-Ting Hsu, Pei-Chi Wu   +5 more
doaj   +1 more source

Synthetic estrogen and progestin effects on the myogenic program following damage in C2C12 murine myoblasts

Physiological Reports, Volume 14, Issue 8, April 2026.
The effect of oral contraceptives (OCs) on muscle repair is unknown. Using electrical pulse stimulation to simulate damage in C2C12 myoblasts treated with four OC generations (MPA, LNG, DSG, DRP combined with ethinyl estradiol), we assessed proliferation, differentiation, migration, creatine kinase, myogenic proteins, and hormone receptor protein ...
Mai Wageh, Michael Kamal, Gianni Parise
wiley   +1 more source

Effects of Dienogest on Surgically Induced Endometriosis in Rats after Repeated Oral Administration

, 2011
<i>Background:</i> Dienogest demonstrates efficacy for lesion reduction and pain relief in clinical trials of endometriosis. The current study investigated an intraperitoneal animal model of endometriosis to further characterize the effects ...
O.M. Fischer, U. Kaufmann-Reiche, U. Fuhrmann, C. Moeller   +3 more
core   +1 more source

Ovarian reserve may influence the outcome of bone mineral density in patients with long-term use of dienogest

SAGE Open Medicine, 2021
Objective: Long-term administration of dienogest, which is known to have effect on bone mineral density, is frequently done in patients with endometriosis and adenomyosis, but a few studies focused on the bone mineral density changes after finishing the ...
N Yamamoto, O Wada-Hiraike, M Hirano, T Hirata, M Harada, Y Hirota, K Koga, T Fujii, Y Osuga   +8 more
doaj   +1 more source

Uso de Dienogest para el tratamiento de la endometriosis: revision sistematica de la literatura.

, 2012
La endometriosis es una entidad frecuente en ginecología para la que desafortunadamente aun no se tiene un tratamiento del todo efectivo. En los últimos años se ha propuesto el uso de Dienogest, una progestina selectiva, con buenos resultados.
Negret Delgado, María del Pilar, Vallejo Ortega, María Teresa, Vallejo Ortega, María   +2 more
core   +1 more source

Effectiveness of dienogest in improving quality of life in Asian women with endometriosis (ENVISIOeN): interim results from a prospective cohort study under real-life clinical practice

BMC Women's Health, 2019
Background Dienogest has been shown to substantially improve endometriosis-associated symptoms such as debilitating chronic pelvic pain, and in turn, health-related quality of life (HRQoL).
Kitirat Techatraisak, Andon Hestiantoro, Soon Ruey, Maria Jesusa Banal-Silao, Mee-Ran Kim, Seok Ju Seong, Syarief Thaufik, Christiane Ahlers, So Young Shin, Byung Seok Lee   +9 more
doaj   +1 more source

Environmental photochemistry of dienogest: phototransformation to estrogenic products and increased environmental persistence via reversible photohydration

, 2017
Potent trienone and dienone steroid hormones undergo a coupled photohydration (in light)-thermal dehydration (in dark) cycle that ultimately increases their environmental persistence.
Wammer, Kristine H.
core   +1 more source