Results 61 to 70 of about 2,746 (190)

Effectiveness of dienogest in improving quality of life in Asian women with endometriosis (ENVISIOeN): interim results from a prospective cohort study under real-life clinical practice

BMC Women's Health, 2019
Background Dienogest has been shown to substantially improve endometriosis-associated symptoms such as debilitating chronic pelvic pain, and in turn, health-related quality of life (HRQoL).
Kitirat Techatraisak, Andon Hestiantoro, Soon Ruey, Maria Jesusa Banal-Silao, Mee-Ran Kim, Seok Ju Seong, Syarief Thaufik, Christiane Ahlers, So Young Shin, Byung Seok Lee   +9 more
doaj   +1 more source

A concept for a new approach to combined oral contraception from adolescence to perimenopause: Continuous use of the oral GnRH antagonist Relugolix and the fetal estrogen Estetrol

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 4, Page 568-574, April 2026.
It is expected that the relugolix estetrol combination RE4W will enable women to control their fertility and prevent menstrual cycle related problems, while offering a smooth transition through perimenopause into the postmenopause and decrease the risk of breast cancer.
Herjan J. T. Coelingh Bennink, Karolina Afors, Luis Bahamondes, Alessandra Graziottin, Deborah Bateson, Teresa Bombas, Yutaki Osuga, Santiago Palacios, Carolyn L. Westhoff, Kristina Gemzell‐Danielsson   +9 more
wiley   +1 more source

Associations between androgen levels and endurance training‐induced changes in body composition and physical performance in premenopausal females

Physiological Reports, Volume 14, Issue 7, April 2026.
Abstract We investigated whether a moderate‐intensity continuous training (MICT) for two menstrual/contraceptive cycles (~8 weeks) alters endogenous androgen concentrations in premenopausal females, and whether baseline androgen concentrations or their changes from baseline to post‐intervention are associated with adaptations in body composition and ...
Vera M. Salmi, Jari E. Karppinen, Maarit Lehti, Heikki Kyröläinen, Johanna K. Ihalainen, Ritva S. Mikkonen   +5 more
wiley   +1 more source

Synthetic estrogen and progestin effects on the myogenic program following damage in C2C12 murine myoblasts

Physiological Reports, Volume 14, Issue 8, April 2026.
The effect of oral contraceptives (OCs) on muscle repair is unknown. Using electrical pulse stimulation to simulate damage in C2C12 myoblasts treated with four OC generations (MPA, LNG, DSG, DRP combined with ethinyl estradiol), we assessed proliferation, differentiation, migration, creatine kinase, myogenic proteins, and hormone receptor protein ...
Mai Wageh, Michael Kamal, Gianni Parise
wiley   +1 more source

Uso de Dienogest para el tratamiento de la endometriosis: revision sistematica de la literatura.

, 2012
La endometriosis es una entidad frecuente en ginecología para la que desafortunadamente aun no se tiene un tratamiento del todo efectivo. En los últimos años se ha propuesto el uso de Dienogest, una progestina selectiva, con buenos resultados.
Negret Delgado, María del Pilar, Vallejo Ortega, María Teresa, Vallejo Ortega, María   +2 more
core   +1 more source

Efficacy of oral contraceptive pills versus dienogest on endometriosis pain scores: a prospective cohort study

Middle East Fertility Society Journal
Background Endometriosis is a chronic gynecological condition associated with pelvic pain, dysmenorrhea, dyspareunia, and impaired quality of life. Medical management aims to reduce symptoms and prevent recurrence. The primary objective of this study was
Mahmoud Abdallah, Asmaa S. Mohamed, Ahmed Soliman, Walid M. Tawfik   +3 more
doaj   +1 more source

Dienogest use and the risk of breast and gynecologic cancers: A nationwide population‐based study

International Journal of Gynecology &Obstetrics, Volume 172, Issue 2, Page 1123-1129, February 2026.
Abstract Objective To evaluate whether dienogest exposure is associated with the risk of breast, endometrial, or tubo‐ovarian cancer in women with endometriosis. Methods In this nationwide retrospective cohort study (January 2012 to December 2023), we used the Korean National Health Insurance Review & Assessment Service database. Women aged 20–49 years
Hoyol Jhang, Saerom Kim, Hyun‐Tae Park, Ju‐Young Shin, Seung‐Ah Choe   +4 more
wiley   +1 more source

Non-inferiority study to compare the efficacy of relugolix with dienogest for endometriosis-associated pain and usefulness of administering relugolix prior to dienogest (READY study): study protocol for a multicenter randomized controlled study

Trials
Background Endometriosis presents as endometrial tissue growths outside the uterine cavity with its major symptoms including dysmenorrhea and infertility.
Fuminori Taniguchi, Motoko Fukui, Yutaka Osuga, Tasuku Harada, Jo Kitawaki   +4 more
doaj   +1 more source

Post Hoc Analysis of a Previous Study of Estetrol 15 mg/Drospirenone 3 mg Combination for Dysmenorrhea and Uterine Bleeding in Adenomyosis Patients

Reproductive Medicine and Biology, Volume 25, Issue 1, January/December 2026.
ABSTRACT Purpose To clarify the efficacy and safety of the estetrol 15 mg/drospirenone 3 mg combination among Japanese women with adenomyosis by post hoc analyses of a previous randomized clinical study. Methods Post hoc analyses were performed using data from a 16‐week, multi‐center, randomized, double‐blinded, placebo‐controlled, parallel‐group study,
Tasuku Harada, Takao Kobayashi, Eri Koga, Masayoshi Nogami, Ayaka Sasahara, Toshiaki Takayanagi, Masashi Hirayama, Yutaka Osuga   +7 more
wiley   +1 more source

Effect of Elagolix in comparison to Dienogest in the treatment of symptomatic adenomyosis [PDF]

Background: Adenomyosis, a benign gynecological disorder, is diagnosed with increasing frequency in infertile patients since women delay their first pregnancy.
Anwary, Shaheen Ara, Banu, Jesmine, Ishrat, Shakeela, Jubaida, Umme, Sultana, Rebeka, Deeba, Farzana, Alamgir, Chowdhury Faisal, Darmini, Maliha   +7 more
core   +1 more source