Results 31 to 40 of about 1,963,474 (292)

The calorically restricted ketogenic diet, an effective alternative therapy for malignant brain cancer

Nutrition & Metabolism, 2007
Background Malignant brain cancer persists as a major disease of morbidity and mortality in adults and is the second leading cause of cancer death in children. Many current therapies for malignant brain tumors fail to provide long-term management because
Zhou Weihua, Mukherjee Purna, Kiebish Michael A, Markis William T, Mantis John G, Seyfried Thomas N   +5 more
doaj   +1 more source

Restricting carbohydrates to fight head and neck cancer—is this realistic?

Cancer Biology & Medicine, 2014
Head and neck cancers (HNCs) are aggressive tumors that typically demonstrate a high glycolytic rate, which results in resistance to cytotoxic therapy and poor prognosis.
Rainer J. Klement
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Association of low-carbohydrate-diet score and osteoporotic fractures: National Health and Nutrition Examination Survey

Frontiers in Public Health
BackgroundOsteoporotic fractures represent a significant public health concern on a global scale. There is currently a lack of research on the association between low-carbohydrate-diet score and Osteoporotic fractures risk.MethodsA cross-sectional ...
Yuntao Shen, Hebao Wei
doaj   +1 more source

SGLT2 inhibitor versus carbohydrate-restricted isocaloric diet: reprogramming substrate oxidation in type 2 diabetes

Diabetology & Metabolic Syndrome, 2023
Objective Based on the whole-body energy metabolism and insulin action, the difference between increased excretion of carbohydrate in urine by SGLT2i and reduced same amount of oral carbohydrate intake are scarce.
Hiroyuki Igarashi, Hiroshi Uchino, Momoko Kanaguchi, Kaori Hisanaga, Genki Sato, Fukumi Yoshikawa, Masashi Furuta, Naohiro Washizawa, Shuki Usui, Masahiko Miyagi, Takahisa Hirose   +10 more
doaj   +1 more source

Impact of Eating a Carbohydrate-Restricted Diet on Cortical Atrophy in a Cross-Section of Amyloid Positive Patients with Alzheimer’s Disease: A Small Sample Study [PDF]

, 2023
BACKGROUND: A carbohydrate-restricted diet aimed at lowering insulin levels has the potential to slow Alzheimers disease (AD). Restricting carbohydrate consumption reduces insulin resistance, which could improve glucose uptake and neural health.
Mihae Kim, Porter, Verna, Siddarth, Prabha, Colby B. Slyapich, John F. Hodes, Kress, Gavin, Bookheimer, Susan, Bookheimer, Tess, Hodes, John, Jared C. Roach, Gavin T. Kress, Verna R. Porter, Bramen, Jennifer, Popa, Emily, Aarthi S. Ganapathi, Tess Bookheimer, Dye, Richelin, Kim, Mihae, Ganapathi, Aarthi, Loong, Spencer, Richelin V. Dye, Susan Y. Bookheimer, Spencer Loong, Stella Panos, Raji, Cyrus, Slyapich, Colby, Togashi, Tori, David A. Merrill, Emily S. Popa, Ryan M. Glatt, Rapozo, Molly, Kyron Pierce, Cyrus A. Raji, Jennifer E. Bramen, Glatt, Ryan, Pierce, Kyron, Prabha Siddarth, Claudia Wong, Wong, Claudia, Panos, Stella, Molly K. Rapozo, Tori Togashi, Roach, Jared, Merrill, David   +43 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

A carbohydrate restricted diet is superior to a low‐fat diet in subjects with metabolic syndrome

The FASEB Journal, 2006
Metabolic syndrome is associated with high triglycerides, low HDL cholesterol, and a predominance of small LDL particles. We compared the effects of a standard American Heart Association low‐fat diet (<30% fat, <10% saturated fat) to a carbohydrate (CHO) restricted diet (about 10% carbohydrate) in overweight men and women with high TG (>150 mg/
Michael J Puglisi, Maria Luz Fernandez, Cassandra E Forsythe, Erin E Quann, Richard J Wood, Matthew J Sharman, Ricardo Silvestre, Daniel A Judelson, Linda M Yamamoto, Bulent Sokmen, Disa L Hatfield, William J Kraemer, Jeff S Volek   +12 more
openaire   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Effects of a Carbohydrate-Restricted Diet on Affective Responses to Acute Exercise among Physically Active Participants

, 2003
Currently, the carbohydrate-restricted diet is very popular. Atkins' book, Dr. Atkins' Diet Revolution, has sold millions in its more than 25 years of existence.
Simon Driver, Brian D. Butki, Jeffrey Baumstark   +2 more
core   +1 more source