Results 41 to 50 of about 95,806 (307)

Restricting carbohydrates to fight head and neck cancer—is this realistic?

Cancer Biology & Medicine, 2014
Head and neck cancers (HNCs) are aggressive tumors that typically demonstrate a high glycolytic rate, which results in resistance to cytotoxic therapy and poor prognosis.
Rainer J. Klement
doaj   +1 more source

Treatments for women with gestational diabetes mellitus: an overview of Cochrane systematic reviews [PDF]

, 2018
Background Successful treatments for gestational diabetes mellitus (GDM) have the potential to improve health outcomes for women with GDM and their babies. Objectives To provide a comprehensive synthesis of evidence from Cochrane systematic reviews of
Alsweiler, Jane, Brown, Julie, Crowther, Caroline A, Downie, Michelle R, Martis, Ruth, Shepherd, Emily   +5 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Restricted feeding benefits the growth performance and glucose homeostasis of blunt snout bream Megalobrama amblycephala fed high-carbohydrate diets

Aquaculture Reports, 2020
This study was conducted to investigate the effects of restricted feeding on the growth performance, glycolipid metabolism and glucose homeostasis of Megalobrama amblycephala fed a high-carbohydrate (HC) diet.
Chao Xu, Wen-Bin Liu, Bing-Ke Wang, Xiang-Fei Li   +3 more
doaj   +1 more source

Evaluating the Effects of Low Carbohydrate and High Protein Diet on Erectile Function in Rats

Sexual Medicine, 2022
: Introduction: Carbohydrate restriction in diet is becoming a popular means of losing weight nowadays, although it has been reported that excessive intake of low-carbohydrate and high-protein (LCHP) diet causes an adverse effect on cardiovascular ...
Tomoya Kataoka, PhD, Junya Hidaka, Jun Suzuki, Taiki Mori, Daigaku Nakamura, Yuji Hotta, PhD, Akimasa Sanagawa, PhD, Yasuhiro Maeda, PhD, Yoko Furukawa-Hibi, PhD, Kazunori Kimura, PhD   +9 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Bioactivity in Whey Proteins Influencing Energy Balance [PDF]

, 2012
Peer-reviewedObesity develops due to energy (food) intake exceeding energy expenditure. Nutrients that reduce the positive energy balance are thus being considered as therapies to combat obesity.
Cotter, Paul D., Korpela, Riitta, McAllan, Liam, Nilaweera, Kanishka, Roche, Helen M.   +4 more
core   +1 more source

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

Comparative effects of different macronutrient compositions for type 2 diabetes management: a systematic review and network meta-analysis of randomized trials

Journal of Health, Population and Nutrition
Background To assess and rank the comparative effects of different exact macronutrient compositions for type 2 diabetes management rather than examining single macronutrients or as a dietary pattern.
Negin Badrooj, Ahmad Jayedi, Sakineh Shab-Bidar   +2 more
doaj   +1 more source

Role of ketogenic and low-carbohydrate diets in the pathogenesis and treatment of obesity and diabetes mellitus type 1 and 2 - A Literature Review

Journal of Education, Health and Sport
Introduction: Ketogenic and low-carbohydrate diets are characterized by a significant reduction in daily carbohydrate intake, resulting in ketone bodies becoming an alternative energy source to glucose.
Dominika Bąk, Julia Buszek, Piotr Czerniak, Adrianna Antoszewska, Weronika Bargiel, Halszka Wajdowicz, Mateusz Warzocha, Aldona Sokołowska   +7 more
doaj   +1 more source