Results 71 to 80 of about 96,048 (284)
INTRODUCTION: Global sugar consumption has increased in the past 50 years; its abusive intake is responsible for peripheral insulin resistance, which causes the metabolic syndrome - obesity, diabetes mellitus, hypertension, and coronary heart disease ...
Roseli Saraiva Moreira Bittar +2 more
doaj +1 more source
The gastrointestinal tract has no clear role in the pathophysiology of noninsulin-dependent diabetes mellitus (NIDDM), but it may be an appropriate site for therapeutic intervention, specifically changes in diet, meal frequency and medications.
Thomas MS Wolever
doaj +1 more source
Effects of a low-carbohydrate diet on glycemic control in outpatients with severe type 2 diabetes
We previously demonstrated that a loosely restricted 45%-carbohydrate diet led to greater reduction in hemoglobin A1c (HbA1c) compared to high-carbohydrate diets in outpatients with mild type 2 diabetes (mean HbA1c level: 7.4%) over 2 years. To determine
Wakai Kenji +3 more
doaj +1 more source
The Ketogenic Diet: An Answer for Autism? [PDF]
Lacking substantial evidence regarding its genetic identity, autism spectrum disorder (ASD) is a remarkably misunderstood condition with limited options for effective treatment.
Perez, Anne
core +1 more source
Targeted Mitochondrial ECSIT Overexpression Attenuates MASH by Increasing OTUD3 Expression
Mitochondrial ECSIT expression is reduced during MASH pathogenesis. Overexpression of mitochondrial ECSIT mitigates steatohepatitis and maintains hepatic metabolic homeostasis. Mechanistically, ECSIT enhances intramitochondrial OTUD3 expression to stabilize SIRT3 through deubiquitination, thus preserving mitochondrial function and impeding disease ...
Yuqing Jiang +11 more
wiley +1 more source
The effect of very low-calorie diets on renal and hepatic outcomes : a systematic review [PDF]
Peer reviewedPublisher ...
Broom, J +3 more
core +3 more sources
Nanozymes Integrated Biochips Toward Smart Detection System
This review systematically outlines the integration of nanozymes, biochips, and artificial intelligence (AI) for intelligent biosensing. It details how their convergence enhances signal amplification, enables portable detection, and improves data interpretation.
Dongyu Chen +10 more
wiley +1 more source
We generated multi‐tissue single‐cell transcriptomic atlases of camels and cattle, uncovering conserved and lineage‐specific cellular features across digestive and metabolic systems. Cross‐species comparisons revealed the evolutionary origin of the camel glandular sac and identified novel cell populations linked to physiological specialization ...
Tao Shi +22 more
wiley +1 more source
Background: The growing epidemics of obesity and metabolic syndrome (MetS) have been accompanied with dietary fat restriction and carbohydrate elevation.
Somayeh Rajaie +3 more
doaj
Our study identifies selenium deficiency as a hallmark of MASH pathogenesis. Dietary selenium supplementation enhances hepatic fatty acid oxidation (FAO) and attenuates MASH progression by activating the PPARα pathway via selenoprotein H (SELENOH). This selenium‐SELENOH‐PPARα nexus redefines the functional scope of selenoproteins, moving from redox ...
Yuwei Zhang +11 more
wiley +1 more source

