Results 51 to 60 of about 504,087 (263)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

The level of physical activity and somatic indicators in relation to the diet quality of students studying in faculties in the discipline of health sciences

Roczniki Panstwowego Zakladu Higieny, 2020
Background. Diet and physical activity are very important lifestyle features with an impact on the development and proper functioning of the body. Objective.
Robert Gajda
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Enhancing cell motility via non-contact capacitively coupled electrostatic field

Scientific Reports
Cellular motility is essential for making and maintaining multicellular organisms throughout their lifespan. Migrating cells can move either individually or collectively by a crawling movement that links the cytoskeletal activity to the adhesion surface.
Isabella Zironi, Tobias Cramer, Alessandro Fuschi, Margherita Cioni, Giada Guerra, Giacomo Giuliani, Maria Calienni, Laura Caramazza, Micaela Liberti, Francesca Apollonio, Daniel Remondini, Gastone Castellani   +11 more
doaj   +1 more source

Parent Diet Quality and Energy Intake Are Related to Child Diet Quality and Energy Intake [PDF]

Journal of the Academy of Nutrition and Dietetics, 2016
Parents' diets are believed to influence their children's diets. Previous studies have not adequately and simultaneously assessed the relationship between parent and child total diet quality and energy intakes.Our aim was to investigate whether parent and child diet quality and energy intakes are related.We conducted a cross-sectional analysis using ...
Shannon M. Robson, Sarah C. Couch, James L. Peugh, Karen Glanz, Chuan Zhou, James F. Sallis, Brian E. Saelens   +6 more
openaire   +4 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Diet quality and diet costs in German children and adolescents [PDF]

European Journal of Clinical Nutrition, 2014
We examined the association between diet costs and diet quality in a sample of children and adolescents using data from the ongoing longitudinal (open cohort) DONALD (Dortmund Nutritional and Anthropometric Longitudinally Designed) study. Children and adolescents aged 4-18 years (255 boys and 239 girls) provided 1100 yearly collected 3-day weighted ...
U, Alexy, V, Schwager, M, Kersting
openaire   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Development of the Saudi healthy eating index (SHEI): a first step toward national diet quality monitoring

BMC Nutrition
Background Diet quality indices serve as standardized tools to evaluate adherence to dietary guidelines and inform nutrition and public health research.
Haya M. Alzeer, Omar Alhumaidan, Sarah Alkhunein, Areej Alkhaldy   +3 more
doaj   +1 more source

Assessing the association between diet quality and sociodemographic factors in young Saudi adults

Frontiers in Nutrition
ObjectiveThis study aimed to evaluate diet quality (DQ) using the Short Healthy Eating Index (sHEI) and explore the relationship between DQ and sociodemographic factors among young adults in Saudi Arabia.MethodsThis observational cross-sectional study ...
Abeer Salman Alzaben, Kholoud Rashed Alresheedi, Huny M. Bakry, Rahaf Abdullah Ozayb, Halah Abdulaziz Aldawsari, Arwa Obaid Alnamshan, Nahla M. Bawazeer   +6 more
doaj   +1 more source