Results 71 to 80 of about 757,698 (311)

A Comprehensive Review on the Therapeutic Effects of Salvia hispanica L. (Chia) on Metabolic Dysfunction–Associated Fatty Liver Disease: Special Focus on Pathogenesis

International Journal of Clinical Practice
Metabolic dysfunction–associated fatty liver disease (MAFLD) is the most common chronic liver condition with a bidirectional relation with multimetabolic disorders. By considering lifestyle interventions as the approved treatment strategy, several herbal
Maryam Parimi, Sara Arefhosseini, Helda Tutunchi, Seyed Rafie Arefhosseini, Mehrangiz Ebrahimi-Mameghani   +4 more
doaj   +1 more source

Are vaspin and omentin-1 related to insulin resistance, blood pressure and inflammation in NAFLD patients? [PDF]

Journal of Medical Biochemistry, 2018
Background: Non-alcoholic fatty liver disease (N AFLD), the hepatic manifestation of insulin resistance, is the most common cause of chronic liver. The present study aimed to investigate the roles of vaspin and omentin-1 in the NAFLD-related pathology ...
Aliasghari Fereshteh, Izadi Azimeh, Jabbari Masoumeh, Imani Bahareh, Pourghassem-Gargari Bahram, Asjodi Foad, Ebrahimi Sara   +6 more
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

The association between diet quality index-international and dietary diversity score with preeclampsia: a case–control study

BMC Women's Health
Background Preeclampsia is a significant complication that occurs during the second half of pregnancy. Recent studies have indicated that dietary factors play a crucial role in the development of preeclampsia. The Diet Quality Index-International (DQI-I)
Parastoo Tolou Hayat, Bahram Pourghassem Gargari, Parvin Sarbakhsh   +2 more
doaj   +1 more source

Predictors of programme adherence and weight loss in women in an obesity programme using meal replacements [PDF]

, 2005
Objective: To explore predictors of programme adherence and weight loss in patients participating in a weight management programme using meal replacements (MR).Design: One hundred and fifty healthy obese women, age 48.5 years (s.d.
Boniface, D, Finer, N, Packianathan, L, Sheikh, M   +3 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Copper status and its relation to abdominal obesity indices and liver function in non-alcoholic fatty liver disease: a case-control study

BMC Research Notes
Objective This study investigated copper (Cu) status in relation to abdominal obesity indices and liver function in patients with non-alcoholic fatty liver disease (NAFLD).
Sara Arefhosseini, Helda Tutunchi, Seyed Rafie Arefhosseini, Seyede Zoha Ghavami, Mehrangiz Ebrahimi-Mameghani   +4 more
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Use of harm reduction strategies in an occupational therapy life skills intervention [PDF]

, 2013
Thesis (M.S.)--Boston UniversityObjectives of Study: Harm reduction intervention strategies have the potential to support positive health outcomes. However, no studies have explored how these strategies can be implemented in an occupational therapy ...
Hellman, Miranda Renee
core   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source