Results 241 to 250 of about 1,717,479 (343)

Pirin Transcriptionally Regulates PLA2G4A To Inhibit Ferroptosis in Colorectal Cancer via Lipid Profile Remodeling

Advanced Science, EarlyView.
This study identifies Pirin (PIR), an iron‐binding protein, as a critical ferroptosis suppressor in colorectal cancer through lipid membrane remodeling. PIR, induced by NRF2 during ferroptotic stress, transcriptionally regulates PLA2G4A to shift cellular lipid composition away from ferroptosis‐permissive polyunsaturated phospholipids.
Wei Shi, Yue Qi Ong, Prativa Majee, Esther SM Wong, Amhed Missael Vargas Velazquez, Kerem Fidan, Pierce Kah‐Hoe Chow, Wai Leong Tam, Ker Kan Tan, Iain Beehuat Tan, Vinay Tergaonkar   +10 more
wiley   +1 more source

Effects of dietary calcium source and quantity on the laying rate, eggshell quality, reproductive tract, liver fat level, and duodenum morphology in Dekalb white laying hens of 90 weeks of age. [PDF]

Poult Sci
Star L, Oosterveer-van der Doelen MAM, Molist F, Gehring R, Santos RR.   +4 more
europepmc   +1 more source

Dietary Nutrient Evaluations in a Cohort of Dogs with Aminoaciduric Canine Hypoaminoacidemic Hepatopathy Syndrome Inform Dietary Targets for Protein, Fat, Sodium, and Calcium

John C. Rowe, Emmy Y. Luo, Martha G. Cline, Michael T. Astor, John P. Loftus   +4 more
openalex   +1 more source

Metabolomic changes in fatty liver can be modified by dietary protein and calcium during energy restriction

, 2008
Taru K. Pilvi, Tuulikki Seppänen‐Laakso, Helena Simolin, Piet Finckenberg, Anne Huotari, Karl‐Heinz Herzig, Riitta Korpela, Matej Orešič, Eero Mervaala   +8 more
openalex   +2 more sources

Neuroprotective Effects of Time‐Restricted Feeding Combined With Different Protein Sources in MPTP‐Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism

Advanced Science, EarlyView.
Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.
Ting Li, Jian Wu, Sheng‐Yang Zhou, Ming‐An Li, Li‐Ping Zhao, Ao Wang, Yi‐Zhi Song, Wen‐Yan Huang, Lu‐Lu Tan, Chen‐Meng Qiao, Wei‐Jiang Zhao, Chun Cui, Yan‐Qin Shen   +12 more
wiley   +1 more source

Renal expression of calcium and phosphorus transporters: contrasting responses to dietary calcium and microbial phytase in broilers and growing pigs. [PDF]

Br J Nutr
Hu Y, Bikker P, Hendriks WH, van Krimpen MM, van Baal J.   +4 more
europepmc   +1 more source

Tobacco Smoke Exposure From Prenatal To Adolescent Periods Drives IBD Pathogenesis: Dynamic DNA Methylation Signatures Across Lifespan Stages

Advanced Science, EarlyView.
This study illustrates that maternal smoking during pregnancy (MSDP) is an independent risk factor for IBD in offspring, and DNA methylation serves as a key mechanistic pathway connecting early‐life smoking exposure with IBD risk in offspring. That highlights the urgent need for preventive interventions targeting prospective parents and minors to ...
Han Zhang, Jianhui Zhao, Jie Chen, Xinyi Ma, Siyun Zhou, Alexandra Noble, Rahul Kalla, Judith Wellens, Kun Liu, Evropi Theodoratou, Jack Satsangi, Xue Li   +11 more
wiley   +1 more source

Translatomics reveals the role of dietary calcium addition in regulating muscle fat deposition in pigs. [PDF]

Sci Rep
Yu J, Li X, Qi X, Ding Z, Su S, Yu L, Zhou L, Li Y.   +7 more
europepmc   +1 more source

The Effect of Dietary Calcium Levels on Fecal Steroid Excretion in Rats.

, 1997
Tsutomu Miura, Mariko Uehara, Kazuharu Suzuki, Shiro Goto   +3 more
openalex   +2 more sources

SETDB2 Mitigates Podocyte Dysfunction in Diabetic Kidney Disease Through Epigenetic Silencing of SMAD3

Advanced Science, EarlyView.
SETDB2 epigenetically represses Smad3 transcription by increasing H3K9me3 enrichment at its promoter, thereby mitigating podocyte dysfunction in DKD. The transcription factor TCF21 binds directly to the Setdb2 promoter and enhances its expression in podocytes. Abstract Podocyte dysfunction represents both an early pathological hallmark and a key driver
Lanfang Li, Shimin Jiang, Qi Jin, Peng Qu, Yingjie Guo, Xushan Lan, Xinyu Li, Cuiting Sun, Sinan Ai, Xin Li, Weiliang Sun, Jing Guo, Wenge Li, Liang Peng, Lihong Liu   +14 more
wiley   +1 more source