Polyphenolic extracts and their fractions from five plant sources inhibit calcium oxalate and brushite crystal formation in vitro, with non‐anthocyanin fractions showing stronger anti‐lithogenic effects supported by molecular docking. ABSTRACT Nephrolithiasis, or kidney stone formation, is a widespread global health concern.
Mudassir Nazir+5 more
wiley +1 more source
Pharmacokinetic Prediction and Cytotoxicity of New Quercetin Derivatives
ABSTRACT Quercetin (QUE) possesses various pharmacological properties; however, its low bioavailability and solubility hinder its beneficial effects. Enzymatic glycosylation has been explored to improve these aspects. In the present study, we used a sucrose phosphorylase variant to catalyze the regioselective transglucosylation of QUE, predicted the ...
Michele Goulart dos Santos+8 more
wiley +1 more source
In-depth characterization of a selection of gut commensal bacteria reveals their functional capacities to metabolize dietary carbohydrates with prebiotic potential. [PDF]
Bedu-Ferrari C+10 more
europepmc +1 more source
This study reports the total synthesis of α‐galacto‐oligosaccharides (α‐GOSs) 1‐6 with different galactose chain lengths was achieved by the boron‐mediated aglycon delivery , and their immune‐enhancing activities in macrophage J774.1 cells. The results indicate that α‐GOS 2 exhibits the highest promotion of macrophage phagocytosis and increasing ...
Jikun Meng+3 more
wiley +1 more source
Dietary Carbohydrates and Insulin Resistance in Adolescents from Marginalized Areas of Chiapas, México. [PDF]
Castro-Quezada I+9 more
europepmc +1 more source
Chemical Switching: A Concept Inspired by Strategies from Biocatalysis and Organocatalysis
Chemical Switching is introduced as a novel technology that exploits the promiscuity of enzymatic transformations by applying small molecule organocatalytic switches (ORCAs) or gain‐of‐function protein variants. The modulation of underlying chemical principles thereby amplifies low‐rate or installs otherwise absent enzymatic activities to dominate ...
Torkild Visnes+5 more
wiley +1 more source
Impaired Carbohydrate Metabolism among Women with Chronic Low Back Pain and the Role of Dietary Carbohydrates: A Randomized Controlled Cross-Over Experiment. [PDF]
Elma Ö+7 more
europepmc +1 more source
ABSTRACT Background and Objectives This study aimed to compare the effects of dehulling and ultrasound treatment on rat‐eyed bean protein concentrates' physicochemical and functional properties. Thus, whole bean protein (WBP), dehulled bean protein (DBP), ultrasound‐treated whole bean protein (WBPU), and ultrasound‐treated dehulled bean protein (DBPU ...
Uyory Choe+2 more
wiley +1 more source
Effects of a 10-Week Exercise and Nutritional Intervention with Variable Dietary Carbohydrates and Glycaemic Indices on Substrate Metabolism, Glycogen Storage, and Endurance Performance in Men: A Randomized Controlled Trial. [PDF]
Moitzi AM+5 more
europepmc +1 more source
Contemporary Perspectives on Chronic Renal Disorders
ABSTRACT The prevalence of renal diseases and its associated burden on healthcare have tremendously risen in the past few years. From simple markers assessing kidney function, current renal research delves into understanding the diseases at the cellular and molecular levels and not just at treating, but at improving quality of life, arresting ...
Deenadhayalan Ashok+5 more
wiley +1 more source