Results 51 to 60 of about 148,838 (260)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

The influence of farm production diversity on women’s dietary quality in Ethiopia

Discover Food
Malnutrition remains a significant global challenge, particularly in low- and middle-income countries, such as Ethiopia, where the great majority of smallholder farm households rely on agriculture as a crucial source of both food and income.
Temesgen Awoke Yalew, Alebel B. Weldesilassie, Stephen Thornhill, Edward Lahiff   +3 more
doaj   +1 more source

Maternal dietary diversity and pattern during pregnancy is associated with low infant birth weight in the Cape Coast metropolitan hospital, Ghana: A hospital based cross-sectional study

Heliyon, 2020
Background: This study investigated the associations between mother's dietary diversity score and dietary patterns during pregnancy and the odds of low birth weight at the Cape Coast Metropolitan Hospital in Ghana.
Dan Yedu Quansah, Daniel Boateng
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Measurement and spatiotemporal evolution characteristics of dietary diversity among Chinese residents

Frontiers in Nutrition
PurposeThe purpose of this paper is to measure the dietary diversity and to analyze the regional characteristics, differences, and evolutionary trends of dietary diversity among Chinese residents.MethodsIn this paper, the dietary diversity among Chinese ...
Guangyuan Qin, Miaomiao Li, Shiwen Quan
doaj   +1 more source

Spatial variation and determinates of dietary diversity among children aged 6–23 months in Ethiopia: spatial and multilevel analysis using Ethiopian Demography Health Survey (EDHS) 2019

Archives of Public Health, 2022
Background Minimum dietary diversity is the consumption of five or more food groups from the eight World Health Organization recommended food groups.
Tewodros Getaneh Alemu, Masresha Asmare Techane, Chalachew Adugna Wubneh, Nega Tezera Assimamaw, Getaneh Mulualem Belay, Tadesse Tarik Tamir, Addis Bilal Muhye, Destaye Guadie Kassie, Amare Wondim, Bewuketu Terefe, Bethelihem Tigabu Tarekegn, Mohammed Seid Ali, Beletech Fentie, Almaz Tefera Gonete, Berhan Tekeba, Selam Fisiha Kassa, Bogale Kassahun Desta, Amare Demsie Ayele, Melkamu Tilahun Dessie, Kendalem Asmare Atalell   +19 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

The effects of dietary diversity on health status among the older adults: an empirical study from China

BMC Public Health
Background Dietary diversity is an indicator of nutrient intake among the elderly. Previous researches have primarily examined dietary diversity and the risks with chronic and infectious disease and cognitive impairment, limited evidence shows the ...
Yali Zhu, Qiaozhen An, Jiahao Rao
doaj   +1 more source

Maternal dietary diversity and micronutrient adequacy during pregnancy and related factors in East Gojjam Zone, Northwest Ethiopia, 2016

BMC Pregnancy and Childbirth, 2019
Background Monotonous and less diversified diets are associated with micronutrient deficiency. Evidence on maternal dietary intakes during pregnancy is essential to achieve the 2025 global nutrition target and reduce maternal and child mortalities.
Tebikew Yeneabat, Haweni Adugna, Tarekegn Asmamaw, Muluken Wubetu, Melaku Admas, Getachew Hailu, Asres Bedaso, Tadele Amare   +7 more
doaj   +1 more source