Results 71 to 80 of about 17,112 (264)

Toxic Effects Of Corn Oil On Liver Histology In Albino Rats

Journal of Bahria University Medical and Dental College, 2015
Objective: To evaluate whether high quantities of unsaturated fats such as corn oil can produce fatty liver in albino rats. Materials and Methods: This experimental study was carried out at BMSI, JPMC after obtaining ethical approval, from October to ...
Aisha Qamar, Humera Waqar, Asma Siddiqui, Hemant Kumar, Mohammad Saad Saeeduddin   +4 more
doaj  

Fatty Acid Composition, at Equivalent Lipid Exposure, Dictates Human Macrophage Polarization via PPARγ Signaling

Cells
Dietary fats are consumed as mixtures, yet it remains unclear whether fatty acid composition, independent of fat content, dictates human macrophage polarization.
Halemah AlSaeed, Hesah Almusallam, Shayndel Menezes, Hessah Almelaifi, Hussah Alonaizi, Mohammad Almejaimi, Rasheed Ahmad, Fatema Al-Rashed   +7 more
doaj   +1 more source

Enhanced peripheral blood mononuclear cell lipid metabolism drives poor immunotherapy response via ferroptotic stress‐induced T cell exhaustion in hepatocellular carcinoma

Interdisciplinary Medicine, EarlyView.
Integrated multi‐omics reveals that CD36‐mediated lipid overload in PBMCs drives T cell exhaustion via sub‐lethal ferroptotic stress and AKT suppression. This systemic metabolic signature serves as a robust predictor of immunotherapy response in HCC, suggesting that modulating lipid metabolism can rescue immune fitness.
Ying Zhu, Zhouyu Ning, Yong Deng, Changjing Huang, Hui Li, Yun Sun, Zhiqiang Meng   +6 more
wiley   +1 more source

Association between empirically driven dietary patterns and cardiometabolic disease risk factors: a cross-sectional analysis in disease-free adults

Nutrition & Metabolism
Background Although links between dietary patterns (DPs) and cardiometabolic disease (CMD) risk markers have been identified in UK populations, these studies often rely on less quantitative measures of dietary assessment and include only a limited number
Arife Yilmaz, Michelle Weech, Vasiliki Bountziouka, Kim G. Jackson, Julie A. Lovegrove   +4 more
doaj   +1 more source

Which diet for an effective cardiovascular prevention?

Monaldi Archives for Chest Disease, 2015
Over the last years, numerous evidence on the existing relationship between nutrition and chronic degenerative diseases have led investigators to search for the optimal dietary pattern to maintain a good health status.
Francesco Sofi, Rosanna Abbate, Gian Franco Gensini, Alessandro Casini   +3 more
doaj   +1 more source

Mitochondria‐targeted nanomedicine for cancer therapy: Targeting strategies, therapeutic mechanisms, and translational challenges

Interdisciplinary Medicine, EarlyView.
This review highlights recent advances in mitochondria‐targeted nanomedicine for cancer therapy. It summarizes key targeting strategies and delineates four principal therapeutic mechanisms: oxidative stress–induced mitochondrial dysfunction, disruption of energy metabolism, direct mitochondrial damage, and induction of immunogenic cell death.
Linfeng Xiao, Xiaowei Chang, Jun Zhang, Yinshan Hong, Wenhui Cao, Zhewu Zhao, Yu‐E. Wang, Yanling Yang   +7 more
wiley   +1 more source

High dietary inflammatory index associates with inflammatory proteins in plasma

Diabetology & Metabolic Syndrome
Background and aim Unhealthy dietary habits and highly caloric foods induce metabolic alterations and promote the development of the inflammatory consequences of obesity, insulin resistance, diabetes and cardiovascular diseases.
Elisa Mattavelli, Elisa Piperni, Francesco Asnicar, Laura Redaelli, Liliana Grigore, Fabio Pellegatta, Amir Nabinejad, Sabrina Tamburini, Nicola Segata, Alberico Luigi Catapano, Andrea Baragetti   +10 more
doaj   +1 more source

Three approaches to assessing dietary quality in Mexican adolescents from 2006 to 2018 with data from national health and nutrition surveys

Public Health Nutrition
Objective: To assess trends in the dietary quality of Mexican adolescents from 2006 to 2018, both overall and by sociodemographic indicators, using adaptations of the EAT-Lancet Planetary Health (PH) recommendations, optimal intake estimated by the ...
Elsa Berenice Gaona-Pineda, Nancy López-Olmedo, Hortensia Moreno-Macías, Teresa Shamah-Levy   +3 more
doaj   +1 more source

Biochemical and Molecular Insights Into Monocrotaline‐Induced Hepatotoxicity: An Experimental Mouse Study

Journal of Applied Toxicology, EarlyView.
ABSTRACT Monocrotaline (MCT), a plant‐derived pyrrolizidine alkaloid, is well known for its hepatotoxic effects. However, full elucidation of the mechanisms underlying MCT‐induced hepatotoxicity, as well as the development of reliable biomarkers for early detection and monitoring, requires an integrated evaluation of biochemical, molecular, and ...
Ali Şenol, Alparslan Kadir Devrim, Miyase Çinar, Mahmut Sözmen, Fatma Betül Akça   +4 more
wiley   +1 more source

Microbial communities and functional diversity in seafood

JSFA reports, EarlyView.
Abstract Functional diversity encompasses ecosystem processes that enhance adaptability to environmental change. This study explores the diversity of microorganisms associated with seafood. In this paper, we present our knowledge of microbial diversity in relation to seafood.
Christian Larbi Ayisi, Samuel Ayeh Osei, Grace Afumwaa Boamah, Gertrude Dzifa Mensah   +3 more
wiley   +1 more source