Results 91 to 100 of about 6,165,042 (395)

Dose–Response Relationships of Five Dietary Patterns with the Risk of Cancer: Findings from the UK Biobank Study

Proceedings, 2023
Diet is an important risk factor for cancer. Several approaches for assessing the nutritional quality of diets have been developed and are associated with cancer risk. However, the evidence is limited for some dietary patterns.
Solange Parra-Soto, Katherine Livingstone, Fiona Malcomson, John Mathers, Jill Pell, Frederick Ho, Carlos Celis-Morales   +6 more
doaj   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Dietary patterns and childhood stunting in Zimbabwe

BMC Nutrition, 2022
Background Diet is one important predictor of children’s growth, and often dietary interventions can assist with reversing adverse nutrition outcomes.
Anesu Marume, Moherndran Archary, Saajida Mahomed   +2 more
doaj   +1 more source

Association Between Plant-Based Dietary Patterns and Risk of Type 2 Diabetes: A Systematic Review and Meta-analysis.

JAMA Internal Medicine, 2019
Importance Accumulating epidemiologic evidence has suggested favorable associations between plant-based dietary patterns and risk of type 2 diabetes, although there is a lack of a quantitative summary of evidence substantiating this important association.
F. Qian, Gang Liu, F. Hu, S. Bhupathiraju, Qi Sun   +4 more
semanticscholar   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

The Dietary Pattern in the Iranian Population, Findings of Bandare-Kong Non-communicable Disease Cohort Study: A Brief Report [PDF]

Disease and Diagnosis
Background: The association between dietary patterns and chronic diseases and mortality risk has been demonstrated in recent studies. Considering that dietary patterns can provide an approach that is comprehensive to both disease prevention and treatment,
Shaghayegh Rakhshbahar, Masoumeh Kheirandish, Mehdi Shahmoradi, Elaheh Salarpour, Seyyed Mohammad Hashemi   +4 more
doaj   +1 more source

Associations between Western and Mediterranean-type dietary patterns and anxiety and stress [PDF]

, 2016
In this study we investigated the relationship between dietary patterns and anxiety and stress in adults living in Shiraz, Iran. In a cross-sectional design, 416 subjects (180 men and 236 women) aged 20 to 50 years were selected by stratified multistage ...
Akhlaghi, M., Amanat, S., Dastsouz, F., Kamali, M., Sadeghi, F.   +4 more
core   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

Diet and bone mineral density study in postmenopausal women from the TwinsUK registry shows a negative association with a traditional English dietary pattern and a positive association with wine [PDF]

, 2011
Background: The effect of diet on bone mineral density (BMD) remains controversial, mainly because of difficulties in isolating dietary factors from the confounding influences of age, lifestyle, and genetic factors.
Aedín Cassidy, Alex J MacGregor, Andrew, Begg, Berg, Bingham, Burns, Cashman, Chung, Devine, EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA), Geoffrey R Guile, Harrington, Heaney, Henderson, Jane Skinner, MacInnis, Spector, Susan J Fairweather-Tait, Teucher, Tim D Spector, Tucker, Whiting, Willett, Williams   +24 more
core   +1 more source

Heritability of dietary food intake patterns [PDF]

Acta Diabetologica, 2012
The quality and quantity of food intake affect body weight, but little is known about the genetics of such human dietary intake patterns in relation to the genetics of BMI. We aimed to estimate the heritability of dietary intake patterns and genetic correlation with BMI in participants of the Erasmus Rucphen Family study.
Berg, L. van den, Henneman, P., Dijk, K.W. van, Delemarre-van de Waal, H.A., Oostra, B.A., Duijn, C.M. van, Janssens, A.C.J.W.   +6 more
openaire   +4 more sources