Results 71 to 80 of about 3,705,689 (305)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

The association of dietary patterns with latent tuberculosis infection among young adults: A case-control study in Shanghai

Journal of Infection in Developing Countries
Introduction: In developing and underdeveloped countries, undernutrition plays a major role in subverting the immune system, leading to an increase in TB infections; this study investigated the associations between dietary patterns and latent ...
Yu Siyu, Li Shihong, Liu Yang, Jiang Yue, Cai Fengzhu, Xiao Shaotan, Hao Lipeng, He Gengsheng   +7 more
doaj   +1 more source

Personality Traits and Eating Habits in a Large Sample of Estonians [PDF]

, 2012
Objectives: Diet has health consequences, which makes knowing the psychological correlates of dietary habits important. Associations between dietary habits and personality traits were examined in a large sample of Estonians (N = 1,691) aged between 18 ...
Allik, Jueri, Esko, Tonu, Deary, Ian J., Realo, Anu, Mõttus, Rene; id_orcid, Metspalu, Andres   +5 more
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Dietary Patterns and Mortality in a Multinational Cohort of Adults Receiving Hemodialysis

, 2019
Rationale & Objective: Clinical practice guidelines for dietary intake in hemodialysis focus on individual nutrients. Little is known about associations of dietary patterns with survival.
Teixeira-Pinto, A, Garcia-Larsen, V, Carrero, JJ, Natale, P, Campbell, K, Wong, G, Murgo, AM, Tonelli, M, Ruospo, M, Stenvinkel, P, Johnson, DW, Saglimbene, VM, Gargano, L, et al., Palmer, SC   +14 more
core   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

The associations between dietary pattern of chronic obstructive pulmonary disease patients and depression: a cross-sectional study

BMC Pulmonary Medicine, 2021
Background Chronic obstructive pulmonary disease (COPD) is a common lung disease during middle age which one of its complications is depression. Depression is considered one of the major causes of severe disability worldwide.
Fahimeh Dinparast, Akbar Sharifi, Sara Moradi, Maedeh Alipour, Beitullah Alipour   +4 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Dietary patterns.

, 2016
(A) Characteristics of dietary patterns at age 15 years. (B) Characteristics of dietary patterns at age 18 years.
Carla Lopes (849630), Maria Cecília Formoso Assunção (627461), Milton Severo (708962), Bruna Celestino Schneider (2265502), Samuel de Carvalho Dumith (2265505)   +4 more
core   +1 more source