Results 61 to 70 of about 270,810 (258)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Dietary patterns and hepatocellular carcinoma risk: a systematic review and meta-analysis of cohort and case–control studies

Nutrition & Metabolism
Background Globally, HCC presents a significant health burden, characterized by high incidence and mortality rates. Epidemiological studies have increasingly suggested a link between dietary patterns and the risk of hepatocellular carcinoma (HCC), yet ...
Wenxi Shu, Ling Liu, Jiaojiao Jiang, Qinghua Yao   +3 more
doaj   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Exploring Dietary Patterns and Their Associations with Obesity in School-Aged Children in Croatia: A Cross-Sectional CroCOSI Study

Dietetics
Background: While previous research on children’s diets has primarily focused on individual nutrients or foods, recent years have seen increasing attention to the analysis of dietary patterns.
Jasmina Hasanović, Helena Križan, Zvonimir Šatalić, Sanja Musić Milanović   +3 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Association between dietary pattern and cardiometabolic risk in children and adolescents: a systematic review

Jornal de Pediatria (Versão em Português), 2017
Objective: To evaluate the association between dietary patterns and cardiometabolic risk factors in children and adolescents. Data source: This article followed the recommendations of PRISMA, which aims to guide review publications in the health area ...
Naruna Pereira Rocha, Luana Cupertino Milagres, Giana Zarbato Longo, Andréia Queiroz Ribeiro, Juliana Farias de Novaes   +4 more
doaj   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Patterns and clusters of diet in relation to metabolic syndrome among adults in Ubungo (urban) and Kilindi (rural) districts, Tanzania: a cross-sectional study

BMC Public Health
Background The prevalence of Metabolic Syndrome (MetS) is rising worldwide, with particularly high rates in regions undergoing rapid urbanization and dietary change, such as Sub-Saharan Africa (SSA).
Linda S. Paulo, Gonçalo J. Piedade, Simeon Mayala, Vanessa Harris, Virissa C. Lenters, Daniel R. Mende, Appolinary Kamuhabwa, Gideon Kwesigabo, Folkert W. Asselbergs, Pilly Chillo, K. Klipstein-Grobusch   +10 more
doaj   +1 more source

A social-ecological trap theory-informed investigation of dietary patterns in southwestern Madagascar

Frontiers in Nutrition
BackgroundSocial-ecological trap theory highlights the potential for food systems and the social and environmental contexts within which they are situated to ‘trap’ individuals into a trajectory of specific nutritional outcomes when their physical or ...
Heather Kelahan, Stephanie M. Wu, Hervet Randriamady, Aroniaina Falinirina, Madeleine Rasoanirina, Frédéric Déclerque, Marc Y. Solofoarimanana, Jean C. Mahefa, Eric B. Rimm, Eric B. Rimm, Jessica Fanzo, Aaron C. Hartmann, Aaron C. Hartmann, Emma Gibbons, Gildas Todinanahary, Sebastien Haneuse, Christopher D. Golden   +16 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source