Results 101 to 110 of about 7,153,617 (325)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Starch and oil in the donor cow diet and starch in substrate differently affect the in vitro ruminal biohydrogenation of linoleic and linolenic acids [PDF]

, 2011
Trans isomers of fatty acids exhibit different health properties. Among them, trans-10,cis-12 conjugated linoleic acid has negative effects on milk fat production and can affect human health.
A. Troegeler-Meynadier, A. Zened, Akraim, Baumgard, Choi, Destaillats, Enjalbert, F. Enjalbert, Fuentes, Gervais, Glasser, Griinari, Griinari, Griinari, Harfoot, Ip, Jouany, Kalscheur, Kemp, Kemp, L. Cauquil, Legendre, Loisel, Loor, Loor, Lourenço, M.C. Nicot, Michelland, Moate, Park, Piperova, Pottier, Privé, Roy, S. Combes, Shingfield, Tricon, Troegeler-Meynadier, Troegeler-Meynadier, Van Nevel, Wallace, Weimer, Winkler, Y. Farizon, Yang   +44 more
core   +2 more sources

The importance of healthy dietary patterns in chronic disease prevention.

Nutrition Research, 2019
The prevalence of chronic diseases in the United States and around the world is very high and not sustainable by most health care systems. While the etiology is complex, many chronic diseases are preventable through life long practices of adhering to ...
M. Neuhouser
semanticscholar   +1 more source

Nutrients and Dietary Patterns Related to Osteoporosis

Nutrients, 2020
Osteoporosis is a common chronic disease characterized by a decrease in bone mineral density, impaired bone strength, and an increased risk of fragility fractures.
A. Muñoz-Garach, B. García-Fontana, M. Muñoz-Torres   +2 more
semanticscholar   +1 more source

The association of dietary patterns with latent tuberculosis infection among young adults: A case-control study in Shanghai

Journal of Infection in Developing Countries
Introduction: In developing and underdeveloped countries, undernutrition plays a major role in subverting the immune system, leading to an increase in TB infections; this study investigated the associations between dietary patterns and latent ...
Yu Siyu, Li Shihong, Liu Yang, Jiang Yue, Cai Fengzhu, Xiao Shaotan, Hao Lipeng, He Gengsheng   +7 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology

Nature Communications, 2020
Microbiota-host-diet interactions contribute to the development of metabolic diseases. Imidazole propionate is a novel microbially produced metabolite from histidine, which impairs glucose metabolism.
A. Molinaro, Pierre Bel Lassen, Marcus Henricsson, Hao Wu, S. Adriouch, Eugeni Belda, R. Chakaroun, T. Nielsen, Per-Olof Bergh, C. Rouault, S. André, Florian Marquet, F. Andreelli, J. Salem, K. Assmann, J. Bastard, Sofia K. Forslund, E. Le Chatelier, G. Falony, N. Pons, Edi Prifti, B. Quinquis, H. Roume, S. Vieira-Silva, T. Hansen, H. Pedersen, C. Lewinter, Nadja B Sønderskov, Renato Chloe Ehm Astrid Andersson Olivier Jean-Paul Magal Alves Amouyal Galijatovic Barthelemy Batisse Berla, Renato J Alves, C. Amouyal, Ehm Astrid Andersson Galijatovic, O. Barthelemy, J. Batisse, M. Berland, R. Bittar, H. Blottière, Frédéric Bosquet, Rachid Boubrit, O. Bourron, M. Camus, D. Cassuto, J. Chilloux, C. Ciangura, Luis Pedro Coelho, J. Collet, M. Dao, M. Djebbar, A. Doré, L. Engelbrechtsen, S. Fellahi, L. Fezeu, S. Fromentin, P. Giral, J. Gøtze, A. Hartemann, J. Holst, S. Hercberg, G. Helft, M. Hornbak, J. Hulot, R. Isnard, Sophie Jaqueminet, N. Jørgensen, Hanna Julienne, J. Justesen, J. Kammer, N. Krarup, M. Kerneis, J. Khemis, N. B. Kristensen, Michael Kuhn, V. Léjard, F. Levenez, Léa Lucas-Martini, Robin Massey, N. Maziers, Jonathan Medina-Stamminger, G. Montalescot, S. Moutel, Laetitia Pasero Le Pavin, C. Poitou, F. Pousset, Laurence Pouzoulet, Sebastien Schmidt, L. Moitinho-Silva, J. Silvain, Nataliya Sokolovska, Sothea Touch, Mathilde Svendstrup, Timothy Swartz, Thierry Vanduyvenboden, C. Vatier, Stefan Walther, L. Køber, H. Vestergaard, T. Hansen, Jean-Daniel Zucker, P. Galan, M. Dumas, J. Raes, J. Oppert, Ivica Letunic, J. Nielsen, P. Bork, S. Ehrlich, M. Stumvoll, O. Pedersen, J. Aron‐Wisnewsky, K. Clément, F. Bäckhed   +110 more
semanticscholar   +1 more source

Associations of dietary patterns and screen time with depressive symptoms among adolescents in Shandong Province, China

BMC Public Health
Background Understanding the interplay among dietary patterns, screen time, and depressive symptoms among adolescents is crucial for the development of effective prevention strategies. This study aimed to explore the associations between dietary patterns,
Xiaomei Jiang, Zhongyou Li, Pingjing Wen, Yiyi Ling, Hai Li, Jiongli Huang   +5 more
doaj   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Major dietary patterns and their associations with socio-demographic characteristics and obesity among adolescents in Petaling District, Malaysia [PDF]

, 2014
Dietary pattern analysis has emerged as important instruments to identify modifiable dietary risk factors for non-communicable diseases. The aim of this study was to determine the major dietary patterns among adolescents in Petaling District, Selangor ...
Abdul Rahman, Hejar, Garba, Jamila A., Gyanchand Rampal, Lekhraj Rampal, Md. Said, Salmiah   +3 more
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