Results 231 to 240 of about 265,421 (313)

Associations between dietary macronutrient quality and odds of hyperlipidemia: findings from the NEC-Biobank cohort. [PDF]

Nutr J
Li XY, Huang DH, Xu X, Zhang XM, Lv JL, Nan YX, Cao F, Wu QJ, Zhao YH.   +8 more
europepmc   +1 more source

THE EFFECTS OF DIETARY AMINO ACID AND PROTEIN COMPOSITIONS ON COA METABOLISM IN YOUNG ALBINO RATS

, 1967
Tsuneo Nakamura, Tomoichi Kusunoki, Suehisa Kataoka   +2 more
openalex   +2 more sources

RelA Inhibits Embryonic Myogenesis by Coordinately Regulating a Novel Distal Enhancer of Myogenin

Advanced Science, EarlyView.
Maternal obesity (MO) accounts for more than 40% of pregnancies in the United States, induces inflammation, and impairs embryonic myogenesis, known to program muscle dysfunction in offspring. Inflammation enhances the binding of RelA to a novel distal enhancer located 4 kb upstream of myogenin promoter to inhibit embryonic myogenesis, which is ...
Md Nazmul Hossain, Yao Gao, Sharmeen Islam, Li‐Wei Chen, Xinrui Li, Zhongyun Kou, Nathan C Law, Jeanene Marie de Avila, Mei‐Jun Zhu, Min Du   +9 more
wiley   +1 more source

Hydrogen Sulfide Protects Erectile Function Through Stimulation of Antioxidant Defense in the Corpus Cavernosum: Insights From SG1002 Administration and Cystathionine γ-Lyase Knockout. [PDF]

FASEB J
Azeez TA, Rhein PR, Pierre CJ, Ihrig CM, La Favor JD.   +4 more
europepmc   +1 more source

HIGD1A Alleviates Oxidative Stress Related Ovarian Hypofunction by Enhancing Granulosa Cell Functions via NF‐κB/SOD2 Signaling Pathway

Advanced Science, EarlyView.
HIGD1A maintains redox homeostasis in granulosa cells by modulating SOD2‐mediated dismutation of superoxide into H2O2, which is cleared by CAT and GPX enzymes. However, reduced HIGD1A activates the NF‐κB pathway and upregulates SOD2, leading to intracellular H2O2 accumulation due to impaired clearance.
Huiying Li, Siying Cai, Hongbei Mu, Tianli Chang, Xiaofei Wang, Tianyu Tang, Tengyun Dong, Yu Zhang, Ling Zhang, Huaibiao Li, Liquan Zhou, Wenpei Xiang   +11 more
wiley   +1 more source

Reduced Taurine Transporter Expression in Lymphoblastoid Cell Lines From Alzheimer's Disease Patients Compared With Age-Matched Controls: Therapeutic Implications? [PDF]

Drug Dev Res
Gavriel Y, Voinsky I, Klin H, Squassina A, Gurwitz D.   +4 more
europepmc   +1 more source

STK25 Loss Augments Anti‐PD‐1 Therapy Efficacy by Regulating PD‐L1 Stability in Colorectal Cancer

Advanced Science, EarlyView.
This study demonstrates that STK25 depletion facilitates CRC immune escape through the inhibition of PD‐L1 Ser283 phosphorylation‐mediated ubiquitination, and promotes tumor growth. Furthermore, these findings identify STK25 as a potential therapeutic target to trigger antitumor immunity and promote immunotherapy efficacy. Abstract Tumor immune evasion
Xiaowen Qiao, Pu Xing, Hao Hao, Jiangbo Chen, Lin Song, Yifan Hou, Xinying Yang, Kai Weng, Jie Chen, Pin Gao, Tongkun Song, Hong Yang, Tianqi Liu, Yumeng Ran, Bo Chen, Wei Zhao, Jiabo Di, Zaozao Wang, Jun Zhang, Xiangqian Su, Beihai Jiang   +20 more
wiley   +1 more source

Assessment of genetically modified soybean DBN9004 (application EFSA-GMO-BE-2019-165). [PDF]

EFSA J
EFSA Panel on Genetically Modified Organisms (GMO), Casacuberta J, Barro F, Braeuning A, de Maagd R, Epstein MM, Frenzel T, Gallois JL, Koning F, Messéan A, Moreno FJ, Nogué F, Savoini G, Schulman AH, Tebbe C, Veromann E, Ardizzone M, De Sanctis G, Fernández Dumont A, Ferrari A, Gómez Ruiz JÁ, Goumperis T, Kagkli DM, Lewandowska A, Camargo AM, Piffanelli P, Raffaello T, Sánchez-Brunete E.   +27 more
europepmc   +1 more source

PlantGPT: An Arabidopsis‐Based Intelligent Agent that Answers Questions about Plant Functional Genomics

Advanced Science, EarlyView.
PlantGPT integrates 60 000+ plant research articles with Arabidopsis phenotype‐gene data through retrieval‐augmented generation and fine‐tuning of Llama3‐8B. This open‐source, specialized AI system outperforms general large language models in plant gene‐phenotype relationships, establishing a new paradigm for functional genomics research and molecular ...
Ruixiang Zhang, Yu Wang, Weiyang Yang, Jun Wen, Weizhi Liu, Shipeng Zhi, Guangzhou Li, Nan Chai, Jiaqi Huang, Yongyao Xie, Xianrong Xie, Letian Chen, Miao Gu, Yao‐Guang Liu, Qinlong Zhu   +14 more
wiley   +1 more source

Increasing dietary soybean trypsin inhibitor protein attenuates nursery pig performance. [PDF]

Transl Anim Sci
Miller KA, Spencer JD, Krishnan HB, Mendoza OF, McCallum MN, Mahoney JA, Burrough ER, Gabler NK.   +7 more
europepmc   +1 more source